Oncology Flashcards

1
Q

what is wilms tumour aka?

A

nephroblastoma

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2
Q

epidemiology of nephroblastoma?

A

typically <5 years

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3
Q

symptoms of nephroblastoma

A
  • abdo pain
  • haematuria
  • weight loss
  • hypertension
  • lethargy
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4
Q

Ix of nephroblastoma

A
  1. USS
  2. Staging CT
  3. biopsy to confirm
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5
Q

Mx of nephroblastoma

A
  • surgical excision
  • adjuvant chemo/radio
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6
Q

prognosis of nephroblastoma

A

90% 5 year survival

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7
Q

what is neuroblastoma?

A

tumour that arises in neural crest cells in sympathetic nervous system. Can occur anywhere

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8
Q

epidemiology?

A

most common

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9
Q

most common sites of neuroblastoma?

A

adrenal gland & abdomen

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10
Q

presentation of neuroblastoma

A
  • abdo mass
  • weight loss
  • lethargy
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11
Q

diagnosis of neuroblastoma?

A
  • AXR
  • Abdominal US
  • elevated urine catecholamines
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12
Q

Mx of neuroblastoma

A
  • surgery
  • adjuvant chemo / radio
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13
Q

what is retinoblastoma?

A

malignancy of retinal cells

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14
Q

aetiology of retinoblastoma?

A

genetic- 45% hereditary: autsomal dominant

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15
Q

symptoms of retinoblastoma

A
  • squint
  • poor vision
  • absent red reflex
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16
Q

Mx of retinoblastoma

A

surgery, radiotherapy, chemotherapy

17
Q

most common tumours in children, from most to least

A
  • Leukaemia
  • CNS tumour
  • lymphoma
  • neuroblastoma
  • wilms tumour
  • bone tumour
  • retinoblastoma