Flashcards in Opioid Antagonists Deck (15)
Opioids with shortest half life? Longest half life?
Shortest - Remifentanil 3-4mins
Longest - Buprenorphine 4-8hours
Function of opioid receptors?
Mu "Mabagal huminga" (Respiration)
Full agonist opioid analgesic (Mu) that exerts hemodynamic effects on pulmonary circulation? Used for severe pain, chest pain in MI
(Miosis, Ortho hypo, Resp depression (Mu), Pain relief, His release, ICP increase, Nausea, Euphoria)
Most potent full agonist opioid analgesia? Used in breakthrough cancer pain and severe chronic pain (as lollipop)
Ohmefentanyl (OH MY FENTANYL)
18,000 times more potent
Opioid of choice for pancreatitis? Mu and Kappa
(no biliary spasm)
Meperidine fatal if combined with?
Meperidine cause serotonin syndrome if combined with?
Opioid partial agonist also used for cough suppression?
(decreased sensitivity of cough receptors)
Opioid analgesic that causes drug induced hyperthyroidism? Investigated as novel treatment of leukemia
Opioid analgesic used for post herpetic neuralgia and DM nephropathy?
Opioid analgesic withdrawn due to fatal cardiotoxicity? Group 1C
Commonly used in suicides
Opioid analgesic that reduce craving for alcohol? Effects are resistant to naloxone reversal
"Bukas Pre! Inom tayo"
Opioid antagonist for opioid overdose?
Tramadol contraindicated in patients with?
Can produce seizures