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Gastrointestinal - Pathology > Oral Cavity > Flashcards

Flashcards in Oral Cavity Deck (39):
0

What are some disease associations with aphthous ulcers?

Ciliac's disease, inflammatory bowel disease

1

What is a oral fibroma and what is it due to?

Squamous cell and fibrous tissue proliferation due to chronic irritation

2

What is a pyogenic granuloma of the mouth?

Benign lobular proliferation of capillaries in the mouth

3

What can cause glossitis?

B12 deficiency
Other deficiency states

4

What is Plummer-Vinson syndrome?

Iron deficiency anemia
Glossitis
Dysphagia due to esophageal webs

5

Increased neutrophilic proliferation in the epithelium (associated with mild burning sensation) is indicated in what disease?

Geographic tongue

6

What is the name for heterotropic collections of sebaceous glands in the oral cavity?

Fordyce's granules

7

What are the three types of odontogenic cysts?

Dentigerous cyst
Odontogenic keratocyst
Periapical cyst

8

What infectious diseases can manifest in oral changes?

Scarlet Fever
Measles
Mononucleosis
Diphtheria
HIV

9

Which dermatological diseases can manifest in the mouth?

Lichen planus
Pemphigus
Bullous pemphigoid
Erythema multiforme

10

What hematological disorders can manifest in the mouth?

Pancytopenia
Leukemia
Monocytic leukemia

11

What type of patient gets hairy leukoplakia?

HIV, immunocompromised

13

Where is hairy leukoplakia in the mouth and what causes it?

On sides of tongue
EBV

14

What viral infection is associated with squamous papillomas?

HPV

15

What are the two precancerous lesions commonly seen in the oral cavity?

Erythroplakia and leukoplakia

16

What is the histology of leukoplakia?

Hyperkeratosis and irregular epithelial hyperplasia

17

What is actinic cheilitis? What causes it?

Actinic keratosis of the lip
Caused by sun exposure

18

What are the biggest risk factors for squamous cell carcinoma of the oral cavity?

Alcohol and tobacco use, as well as HPV

19

Does HPV squamous cell carcinoma result in a better or worse diagnosis?

Better

20

What gene and which protein are overexpressed in HPV induced SCC?

p16, cyclin dependent kinase inhibitor

21

What cells are indicated in allergic rhinitis?

Eosinophils (REMEMBER LATE PHASE)

22

What is empyema?

A big pocket of pus in the sinus

23

A young adolescent male presents to your office with persistent stuffiness and gets frequent nosebleeds. What is a common diagnosis for this age group?

Nasopharyngeal angiofibroma

24

What are the three types of sinonasal papillomas?

Inverted, exophytic, and oncocytic

25

What are the most common causes of laryngoepiglotitis?

RSV, H. influenza, beta hemolytic strep

26

What are laryngeal squamous papillomas?

Benign papillary squamous neoplasms caused by HPV

27

What is the most common form of laryngeal carcinoma?

squamous cell carcinoma

28

What are the most common causes of xerostomia?

Sjogren's syndrome
Radiation therapy
Antimuscarinics (and other medications)

29

What is sialadenitis?

Inflammation of salivary glands, oftentimes by mumps or staph/strep

30

What is a ranula?

Mucocele from sublingual duct that can dissect into the neck

31

What is lymphoepithelial sialadenitis?

Autoimmune disease involving salivary gland

32

What must lymphoepithelial sialadenitis be distinguished from pathologically?

B cell MALT lymphoma

33

Where do most salivary glands present? Where is it the most malignant?

Parotid gland
Sublingual gland is most malignant

34

Which is the most common salivary gland tumor? Where is it found?

Pleomorphic adenoma
Parotid gland

35

What is the physical exam of the pleomorphic adenoma?

firm, freely movable, painless parotid gland mass

36

What is a Warthin tumor?

tumor of the parotid gland, smokers have 8x the risk

37

What does the histology look like of a warthin tumor?

Dual layer of bland, neoplastic, eosinophilic epithelium

38

What is the most common malignant salivary gland tumor?

Mucoepidermoid carcinoma

39

What is a slow growing salivary gland tumor with predilection for neural invasion?

Adenoid cystic carcinoma