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Flashcards in Liver Testing Deck (11):
1

What does elevated AST and ALT represent?

Hepatocellular damage

2

What does elevated Alkaline phosphatase represent?

Bile duct problems (cholestasis)

3

What does elevated Gamma glutamyl transferase represent?

Bile duct epithelium/cannalicular membrane injury

4

What cellular marker resides in mitochondria?

AST

5

What does ETOH toxicity preferentially elevate?

AST

6

What does a positive ANA test represent?

Autoimmune hepatitis

7

What does a positive anti-smooth muscle antibody test represent?

Autoimmune hepatitis

8

What does decreased ceruloplasmin represent?

Wilson's disease

9

What does a positive AMA-M2 represent?

Primary biliary cirrhosis

10

Why do you do a liver biopsy?

Determine cause of liver disease
Determine extent of damage to the liver

11

What does "Stage" mean for chronic hepatitis? What about "Grade"?

Stage: Degree of fibrosis
Grade: Severity of necro-inflammatory activity