Ovarian Tumors

Question 1

Ovarianc cell types ?

Answer 1

1. Surface epithelium
2. Germ cells
3. Sex cord storma

PATHOMA-145

Question 2

SECa derived from /

Answer 2

Coelomic epithelium

Question 2

Most common type ovarian cancer ?

Answer 2

Surafce epithelium cancer

Question 3

Lining of ovary ?

Answer 3

Coelomic epithelium

Question 3

Benign tumor of surface peithelium cancer of ovary >???

Answer 3

Cystadenoma

Question 4

Cystadenoma common in —

Answer 4

Premanopausal women

Question 4

Coelomic epithelium derivatives ?

Answer 4

1. Fallopian tube-Serous cell
2. Endometrium
3. Endocervix
4. Mucinous cells

Question 5

Common subtypes of ovarian surface epithelial cancer ?

Answer 5

1. Serous tumor =Watery fluid
2. Mucinous tumor = Mucus like fluid

Question 6

Cystadenoma cyst type >

Answer 6

Single + Flat + Simple

Question 7

Malignant tumor of surface epithelium of ovary ?

Answer 7

Cystadenocarcinoma

Question 8

Cystadenocarcinoma common in -

Answer 8

Postmenopausal womnen

Question 9

Cystadenocarcinoma cyst type-

Answer 9

Complex cyst
Shaggy lining

Question 10

Which mutation ?

Answer 10

BRCA1

Question 10

BRCA1 carrier have –

Answer 10

Prophylactic salpingo-oophorectomy + prophylactic mastectomy

Question 11

Less common subtypes of surface epithelium ovarian cancer ?

Answer 11

1. Endometroid tumor
2. Brenner tumors

Question 11

Bladder like epithelium Ca + Benign = ?

Answer 11

Brenner tumors

Question 12

Brenner tumor Histo ?

Answer 12

Coffee bean nuclei on biopsy

Question 13

Cystic teratoma fetal tissue ?

Answer 13

skin hair bone cartilage gut thyroid

Question 13

Serum marker for ovarian cancer ?

Answer 13

CA-125

Question 14

Presentation of surface epithelium ovarian cancer ?

Answer 14

1. Vague abdominal symptoms
2. Pain
3. Fullness
4. Sign of compression
5. Urinary frequency

Question 15

2nd most common ovarian cancer is –

Answer 15

Germ cell tumors

Question 15

Tumor subtypes mimic tissues normally produced by germ cells —-

Answer 15

1. Fetal tissue = Cystic teratoma
2. Oocytes = Dysgerminoma
3. Yolk sac = Endodermal sinus tumor
4. Placental tissue = Choriocarcinoma

Question 16

Cystic teratoma + Thyroid tissue = ?

Answer 16

Struma ovarii

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Question 17

Fried egg appearance in Histo ?

Answer 17

Dysgerminoma

Question 17

Dysgerminoma testicular counterpoint ?

Answer 17

Seminoma

Question 18

Indication of Dysgerminoma ?

Answer 18

inc LDH

Question 18

Dysgerminoma composed of ---

Answer 18

1. Large cells 2. Clear cytoplasm 3. Central nuclei= Represents oocytes

Question 19

Placental tissue germ cell ovarian cancer name ?

Answer 19

Choriocarcinoma

Question 19

Malignant tumor that mimic yolk sac is --

Answer 19

Endodermal sinus tumor

Question 19

Histology of endodermal sinus tumor ?

Answer 19

Schiller duval bodies

Question 20

EST indication ?

Answer 20

inc serum AFP

Question 20

Choriocarcinoma composed of -

Answer 20

1. Cytotrophoblasts 2.Syncytiotrophoblasts

Question 21

Hematogenous spread tumor ?

Answer 21

Choriocarcinoma

Question 21

Beta HCG produced by --

Answer 21

Syncytriotrophoblasts

Question 21

Malignant tumor composed of large primitive cells-

Answer 21

Embryonal carcinoma

Question 21

Choriocarcinoma indication ?

Answer 21

inc Beta-HCG

Question 22

Neoplastic proliferation of granulosa and theca cell ==

Answer 22

G-theca cell tumor =Maliganant

Question 23

Features of sex cord stromal tumors ?

Answer 23

1. Prior to puberty 2. Precocious puberty 3. Menorrhagia 4. Metrorrhagia 5. Postmenopause -most common 6. Endometrial hyperplasia with

Question 24

Histo of granulosa theca cell sex cordnstromal tumor = ?

Answer 24

Call exner bodies =Cell sourrounding bodies filled with pink material

Question 25

Reinke crystals ?

Answer 25

Sertoli leydig cell tumor

Question 26

Benign tumor of fibroblasts=n?

Answer 26

Fibroma

Question 27

Association of fibroma ?

Answer 27

1. Pleural effusion 2. Ascites 3. Meigs syndrome

Question 28

Fate of sertoli leydig cell tumor ?

Answer 28

1. Androgen inc 2. Hiruitism 3. Virilization

Question 29

Krukenberg tumor ?

Answer 29

Metastatic mucinous tumor that involves both ovaries

Question 30

Krukenberg tumor association ?

Answer 30

Metastatic gastric carcinoma - diffuse type

Question 31

Mucinous tumor of the appendix - metastasis to ovary = ?

Answer 31

Pseudomyxoma peritonei | Mucus in the peritoneum ## Footnote PATHOMA-147