What is the mechanism behind an organophosphate insecticide poisoning?
Inhibits acetylcholinesterase = upregulates nicotinix and muscarinic neurotransmission
How does an organophosphate insecticide poisoning present?
Symptoms because of increased acetylcholine
Salivation
Lacrimation
Urination
Defecation/diarrhoea
Cardio - hypotension, brady
Also - small pupils and muscle fasiculation
What is the antidote for an organophosphate insecticide overdose?
Atropine