Pages 220-223 Flashcards Preview

First Aid Step 1 Rapid Review > Pages 220-223 > Flashcards

Flashcards in Pages 220-223 Deck (95)
Loading flashcards...
1

Acanthosis nigricans (hyperpigmentation and
epidermal thickening)

Visceral malignancy (esp. stomach)

2

Actinic keratosis

Squamous cell carcinoma of skin

3

AIDS

Aggressive malignant lymphomas (non-Hodgkin's) and Kaposi's sarcoma

4

Autoimmune diseases (e.g., Hashimoto
thyroiditis, SLE)

Lymphoma

5

Barrett esophagus (chronic GI reflux)

Esophageal adenocarcinoma

6

Chronic atrophic gastritis, pernicious anemia,
postsurgical gastric remnants

Gastric adenocarcinoma

7

Cirrhosis

Hepatocellular carcinoma

8

Cushing syndrome

Small cell lung cancer

9

Dermatomyositis

Lung cancer

10

Down syndrome

ALL (“we ALL fall Down”), AML

11

Dysplastic nevus

Malignant melanoma

12

Hypercalcemia

Squamous cell lung cancer

13

Immunodeficiency states

Malignant lymphomas

14

Lambert-Eaton myasthenic syndrome

Small cell lung cancer

15

Myasthenia gravis, pure RBC aplasia

Thymoma

16

Paget disease of bone

2° osteosarcoma and fibrosarcoma

17

Plummer-Vinson syndrome (r iron)

Squamous cell carcinoma of esophagus

18

Polycythemia

Renal cell carcinoma, hepatocellular carcinoma

19

Radiation exposure

Leukemia, sarcoma, papillary thyroid cancer, and breast cancer

20

SIADH

Small cell lung cancer

21

Tuberous sclerosis (facial angiofibroma, seizures, intellectual disability)

Giant cell astrocytoma, renal angiomyolipoma, and cardiac rhabdomyoma

22

Ulcerative colitis

Colonic adenocarcinoma

23

Xeroderma pigmentosum, albinism

Melanoma, basal cell carcinoma, and especially squamous cell carcinomas of skin

24

BCR-ABL

ASSOCIATED TUMOR
GENE PRODUCT

CML, ALL

Tyrosine kinase

25

bcl-2

ASSOCIATED TUMOR
GENE PRODUCT

Follicular and undifferentiated lymphomas

Anti-apoptotic molecule (inhibits apoptosis)

26

BRAF

ASSOCIATED TUMOR
GENE PRODUCT

Melanoma

Serine/threonine kinase

27

c-kit

ASSOCIATED TUMOR
GENE PRODUCT

Gastrointestinal stromal tumor (GIST)

Cytokine receptor (for stem cell factor)

28

c-myc

ASSOCIATED TUMOR
GENE PRODUCT

Burkitt lymphoma

Transcription factor

29

HER2/neu (c-erbB2)

ASSOCIATED TUMOR
GENE PRODUCT

Breast, ovarian, and gastric carcinomas

Tyrosine kinase

30

L-myc

ASSOCIATED TUMOR
GENE PRODUCT

Lung tumor

Transcription factor