Parasitology Flashcards
what is Medical Parasitology?
the study of invertebrate animals capable of causing disease in humans and animals.
what is a Parasite:
an organism that lives at the expense of another organism (host)
what is the difference between Ectoparasite and Endoparasite
Ectoparasite: on the surface of hosts
Ticks, lice
Endoparasite: within the body of the host
Worms, protozoa
How does a parasite cause damage?
Nutritional deprivation
Direct trauma/obstruction
Inflammation
A successful parasite does not want to kill its host
what are the Modes of Transmission of parasites
1- Via an intermediate, ingestion of larvae in the tissue of another host
2-fecal-oral route, ingesting feces that has eggs or larvae
3-active skin penetration:
4-injection by blood-sucking insects
Giardia lamblia mechanism
a Protozoa that has 2 stages
-first the Cysts (resistant stage) Typically shed in stools, found in Streams, lakes, wild and domestic animals, Contaminated water, fruits and vegetables, the cysts is the Infective stage, its Resistant to chlorination
and it Spread by fecal-oral route (ingestion) needs 10-25 cysts
- the second stage is the Trophozoites caused by gastric acid (active stage) where the parasite Lives in the intestine and attaches to intestinal villi
Giardia lamblia incubation period and symptoms.
Incubation: 1-4 weeks (multiplies by longitudinal binary fission), average 10 days
Symptoms:
Acute, onset of foul smelling, watery diarrhea, cramps, flatulence and steatorrhea.
10-14 days
Diagnosis: microscopy of stool sample, 1/day for 3 days
Naegleria fowleri
mechanism
a Protozoa
found in Soil at the bottom of lakes
Seasonal: summer, warmer temperatures
Transmission: contact with nasal mucosa in people who get immersed in water
Invades nasal mucosa (swims up the nostrils), travels to the brain (and causes neurological infection
look at slid 44 for life cycle
Naegleria fowleri symptoms
Causes Primary Amebic Meningoencephalitis (PAM)
- Intense frontal headache, sore throat, fever, altered sense of taste and smell, nuchal rigidity (stiff neck)
- Death: 4-5 days
- Diagnosis: CSF sample, ameba and red blood cells
what are Helminths,
parasitic worm
what are the types of Helminths with ex
1-Flatworms
- Tapeworms: cestodes
- Flukes: trematodes
2-Roundworms: -nematodes
What is the most common helminth infection in the United States?
pinworms (Enterobius vermicularis)
Enterobius vermicularis mechanism
Pinworms
we get it through the Ingestion of eggs then it Migrates to large intestine then it Mature into adults (2-6 weeks)
Females lay thousands of eggs in the perianal folds
Enterobius vermicularis symptoms, and diagnosis
Symptoms: pruritus, loss of sleep, fatigue
- Scotch tape test
- Treat entire family
Dracunculus medinensis mechanism
Nematode (roundworm)
transmission through Ingestion of intermediate host
-Copepod (animals also can be reservoirs): Cyclops
-then Worm larvae released in the stomach
-then it Penetrate through GI walls
-then it Migrate to extremities (arms and legs)