part 5

Question 1

-inhibits reabsorption of NaCl in the distal convoluted tubule.

Answer 1

Thiazide diuretics: 
chlorothiazide 
chlorthalidone 
hydrochlorothiazide (HCTZ) 
indapamide 
metolazone (zaroxolyn)

Question 2

What are the nursing considerations for thiazide diuretics?

Answer 2

orthostatic hypotension
hyperuricemia
hypokalemia
dehydration

Question 3

what are some adverse effects of thaizide diuretics?

Answer 3

weakness 
muscle cramps 
erectile dysfunction 
hyperglycemia 
hypercalcemia 
pancreatitis
hyperlipidemia 
hypokalemia
hypomagnesemia

Question 4

Reduces K and Na exchange in the DCT. Reduces the excretion of K, H, Ca, and Mg.

Answer 4

K sparing diuretics
Amiloride (Midamor)
Triamterene (Dyrenium)

Question 5

What are the nursing considerations for K sparing diuretics
Amiloride (Midamor)
Triamterene (Dyrenium)

Answer 5

ortho hypotension

hyperkalemia

Question 6

What is a very important consideration for renin inhibitor diuretics (Aliskiren hemifumarate (Tekturna)) and ACE inhibitos?

Answer 6

angioedema - face and airway edema

pt may report scratchy throat or tongue

Question 7

Directly inhibits renin, thus reducing conversion of angiotensin to angiotensin 1.

Answer 7

renin inhibitor diuretics (Aliskiren hemifumarate (Tekturna))

Question 8

Inhibits movement of Ca across the cell membrane resulting in vasodilation. Cardioselective which can result in a decreased HR.

Answer 8

calcium channel blockers: non-dihydropyridines:

• Diltiazem extended release (Cardizem LA)
• Verapamil intermediate release (Calan)
• Verapamil time-release (Verelan PM)
• dipine

Question 9

Causes vascular smooth muscle relaxation resulting in decreased SVR and arterial BP

Answer 9

Calcium channel blockers Dihydropyridines

Question 10

What do the calcium channel blockers Dihydropyridines end in?

Answer 10

-dipine

Question 11

What do the ACE inhibitors end in?

Answer 11

-pril

Question 12

Inhibits ACE and reduces conversion of angiotensin I to angiotensin II. As a result inhibits angiotensin II mediated vasoconstriction.

Answer 12

ACE inhibitors

-pril

Question 13

What are the nursing considerations for ACE inhibitors?

Answer 13

• Aspirin and NSAIDs may reduce effectiveness
• can cause increase in serum cretinine
• inhibits breakdown of bradykinin which can result in dry hacking cough
• can cause retention of K+ (HYPERKALEMIA)
• angioedema