past q 06.05.15

Question 1

What is the effect of the venom of viperid snakes?

Answer 1

Both
 Cardiotoxic
 Neurotoxic

Question 2

Which compound is found in bee venom?

Answer 2

Both
 Histamine
 Hyaluronidase

Question 3

The bites of which ant species cause more severe species?

Answer 3

Solenopsis spp.

Question 4

What is the most toxic part of Poinsetta?

Answer 4

Both
 Sap
 Leaf

Question 5

What is not characteristic to the pharmacokinetic properties of organochlorines?

Answer 5

Quick elimination with the urine.
Characteristic:
 Excellent absorption from the skin and mucous membranes.
 Accumulation in the fat tissue.
 Good distribution, penetration through the blood-brain barrier.

Question 6

Which statement is true of the allergic effect?

Answer 6

The allergic effects are independent of dose.

Question 7

In which type of cells can mutation develop?

Answer 7

Both
 Somatic cells
 Germ cells

Question 8

What is the consequence if a xenobiotic accumulates in the tissues?

Answer 8

Chronic poisoning

Question 9

Which clinical feature is characteristic to sulphur dioxide toxicosis?

Answer 9

Both
 Bronchospasm
 Coughing, hard breathing

Question 10

Which clinical signs are caused by Bleeding heart?

Answer 10

Both
 Opisthothonus
 Hyperexcitability

Question 11

Which antidote is not used in acute organophosphate toxicosis?

Answer 11

Fomepizole
Used:
 Pralidoxim
 Atropine
 Obidoxim

Question 12

Which is a clinical feature of NSAID toxicosis?

Answer 12

Both
 Vomiting, faintness
 Black faeces with melanoma

Question 13

Which mechanism of effect is characteristic to metaldehyde?

Answer 13

Damaging the neurotransmitter in the nerve synapse.

Question 14

Which statement is true of anatomical differences?

Answer 14

The skin of cat is more permeable than that of dog

Question 15

Which statement is true to nitrate-nitrite?

Answer 15

Both
 Methaemoglobin results from the presence of nitrite.
 Monogastric animals are less sensitive to nitrates.

Question 16

Which solution is useful for increasing of glomerular filtration?

Answer 16

Both
 Mannitol solution
 Glucose solution

Question 17

Which antidote is useful in mercury poisoning?

Answer 17

Succimer

Question 18

Which statement is true?

Answer 18

Neither
Neither:
 Selenium has no physiological role in the body, it causes toxicosis also in very small amount nor
 Anaphylactoid reaction can be caused by oral iron administration.

Question 19

Which parameter is the ratio of LD50 and ED50?

Answer 19

Therapeutic index

Question 20

Which mechanism of action is characteristic to diquat?

Answer 20

Fluid loss causes disturbance in the water homeostasis of the organism.

Question 21

Which statement is true for methaldehyde?

Answer 21

The gastric acid facilitates its decomposition.

Question 22

How would you treat xylitol toxicosis in animals?

Answer 22

Infusion containing glucose

Question 23

What is the consequence if a xenobiotic accumulates in the tissues?

Answer 23

Chronic poisoning

Question 24

Antidote in poisoning with diazinon and fenthion

Answer 24

Atropine

Question 25

Which laboratory result is characteristic to haematuria form of Bracken fern poisoning?

Answer 25

Both  Prolonged clotting time  Increased levels of albumin and calcium in serum

Question 26

Which antidote is not used in acute organophosphate toxicosis?

Answer 26

``` Fomepizole Used:  Pralidoxim  Atropine  Obidoxim ```

Question 27

Which is a clinical feature of NSAID toxicosis?

Answer 27

Both  Vomiting, faintness  Black faeces with melanoma

Question 28

Which mechanism of effect is characteristic to metaldehyde?

Answer 28

Damaging the neurotransmitter in the nerve synapse.

Question 29

Which substance or group of substances causes hypertrophy and hyperplasia of the thyroid gland?

Answer 29

Dithiocarbamates

Question 30

Which statement is true of metabolic differences?

Answer 30

In swine, the glucuronic conjugation is more efficient than the sulphate reaction.

Question 31

Which clinical signs are caused by Golden chain?

Answer 31

Both  Vomiting  Diarrhoea, incoordination

Question 32

Which mechanism of action is characteristic to nitrate-nitrite?

Answer 32

It causes dilation of blood vessels via nitrogen monoxide liberation.

Question 33

Which animal species is sensitive to ochratoxin?

Answer 33

Both  Poultry  Swine

Question 34

Which is not a clinical feature of chronic copper toxicosis?

Answer 34

```  CNS signs Clinical features:  Haemolytic crisis  Icterus  Haemoglobinuria ```