Past q 09.12.15

Question 1

Which substances or group of substances causes depression, ataxia, or a ‘narcotic-like’ effect?

Answer 1

Phenocyacetic acid derivatives

Question 2

Which clinical signs are caused in horse by bee or wasp venom?

Answer 2

Both
 Frenzy
 Icterus

Question 3

Which clinical signs are caused by Blue star?

Answer 3

Both
 Mydriasis
 Hypotension

Question 4

Which animal species is the most sensitive to dioxin?

Answer 4

Guinea-pig

Question 5

What are the gross pathological signs in methylxanthine toxicosis?

Answer 5

Both
 Congestion of parenchymal organs
 Gastroenteritis

Question 6

What are the gross pathological findings in sulphur dioxide toxicosis?

Answer 6

Both
 Lung oedema, lung emphysema
 Signs of asphyxia

Question 7

What is the most frequent cause of teratogenic alterations?

Answer 7

Unknown origin multifactorial causes

Question 8

Which mechanism of action is characteristic to dithlocarbamates?

Answer 8

Mutagenic, carcinogenic, teratogenic, and embryotoxic.

Question 9

What are the gross pathological findings in chlorine gas toxicosis?

Answer 9

Both
 Lung oedema
 Severe inflammation of the conjunctiva and the mucous membranes

Question 10

Which compound is found in the poison of poison-arrow frogs?

Answer 10

Batrachotoxin

Question 11

What are the clinical signs of acute lindane toxicosis?

Answer 11

Excitation, aggressivity, convulsions

Question 12

Which medicine is useful in the treatment of poisoning caused by cationic detergents?

Answer 12

Both
 Neutralisation
 DilutionBoth

Question 13

Which process is lethal synthesis?

Answer 13

Both
 The metabolism of diazinon to diazoxon.
 Oxalic acid is produced from ethylene glycol.

Question 14

Which statement is true?

Answer 14

The high calcium content of feed can reduce the absorption of certain compounds.

Question 15

Which clinical sign is not characteristic to ethylene glycol toxicosis?

Answer 15

Icterus
Characteristic:
 Tremors, convulsions
 Vomiting
 Depression

Question 16

This method is routinely used to enhance urinary elimination of toxic…:

Answer 16

Ringer lactate intravenously

Question 17

Which of the following mechanism of effect is characteristic to mercury?

Answer 17

Binds to the sulfhydryl groups of proteins

Question 18

The most toxic substance among these:

Answer 18

Dioxine

Question 19

Which clinical signs are cause by nitrate-nitrite?

Answer 19

Both
 Tachypnoe followed by dyspnoea
 The colour of blood is chocolate brown

Question 20

Which mechanism of effect is characteristic to metaldehyde?

Answer 20

Both
 Severe irritation of the gastrointestinal tract
 Decreasing the concentration of neurotransmitters in the synapses

Question 21

Which antidote is a chelating agent?

Answer 21

Both
 Defenoxamine
 D-penicillamine

Question 22

What is characteristic to the toxicokinetics of endosulphan?

Answer 22

Quick penetration through the blood brain barrier

Question 23

Which clinical signs are caused in dog by bee or wasp venom?

Answer 23

Both
 Facial oedema
 Haemolytic anemia

Question 24

Which is characteristic to urea?

Answer 24

Both
 In an alkaline milieu, the released ammonia is present mainly in its non-ionic form,
 Ammonia released from it is detoxified via urea cycle in the liver.

Question 25

Which statement is true of the allergic effect?

Answer 25

The allergic effects are independent of the dose.

Question 26

Which plant has a hallucinogenic effect?

Answer 26

Blue star

Question 27

Which mechanism of effect is characteristic to sulphur dioxide?

Answer 27

Neither | Neither Stimulates the receptors of glomum caroticum nor Inhibits respiratory enzymes.

Question 28

Which antidote cannot be used in arsenic toxicosis?

Answer 28

``` Deferoxamine Can be used:  D-penicillamine  Na thiosulphate  Dimercaprol ```

Question 29

Which mould fungi produces ochratoxins?

Answer 29

Aspergillus spp.

Question 30

What is characteristic to the kinetic profile of trichothecenes?

Answer 30

They are not accumulated in the body.

Question 31

Which plants cause hepatogenous photosensitivity?

Answer 31

Groundsel spp.

Question 32

When can hydrogen sulphide be formed?

Answer 32

Decomposition of sulphur-containing organic compounds.

Question 33

``` The metabolism of which compound or class of compounds can result in release of carbon disulphide? ```

Answer 33

Dithiocarbamates

Question 34

What are the clinical signs of Formica spp. bites?

Answer 34

Local pain

Question 35

What is the consequence if a xenobiotic binds to the components of the blood?

Answer 35

The rate of excretion is reduced

Question 36

Which is not a clinical feature of metaldehyde poisoning?

Answer 36

```  Behavioural disturbances Clinical features:  Tachypnoe, dyspnoea  Paddling movements  Opisthothonus ```

Question 37

From an aspect of membrane transport which property of the xenobiotic is important?

Answer 37

Both  The degree of ionisation  The size of molecule

Question 38

Which clinical signs are caused by Gloriosa lily spp.?

Answer 38

Both  Numbness of lip, tongue, throat  Haemorrhages, myelosupression

Question 39

Vitamin B1 is useful in:

Answer 39

Both  Horsetail poisoning  Bracken fern poisoning

Question 40

Which is a clinical feature of metaldehyde poisoning?

Answer 40

Both  Paddling movements  Opisthotonus

Question 41

What is characteristic to bipyridyl derivatives?

Answer 41

Both  They are eliminated with the urine within 48 hours  In contact with soil they become soil-bound which is followed by fast degradation

Question 42

What are the clinical signs in acute poisoning by Buckwheat?

Answer 42

Both  Trembling  Hemolysis

Question 43

Which statement is true for methyxanthines?

Answer 43

In higher doses mainly the central nervous system and the kidney are damaged

Question 44

Which clinical feature is characteristic to chlorine gas toxicosis?

Answer 44

Both  Lacrimation, coughing  Lung oedema

Question 45

Which statement is true?

Answer 45

Both  The most sensitive organs to arsenic are the intestine, the kidney and the liver, the most sensitive tissue is the capillary endothelium  Lead is incorporated into the bones during the distribution as tertiary lead phosphate

Question 46

What is characteristic to phenoxyacetic acid derivatives?

Answer 46

Both  Moderately toxic substances  Can increase the nitrate and cyanoglycoside content of plants

Question 47

Which antidote is used in zinc toxicosis?

Answer 47

Both  D-penicillamine  Calcium disodium EDTA

Question 48

What kind of chronic toxic effects are characteristic to organochlorines?

Answer 48

Teratogenicity, estrogen-like effect, thinning of eggshells

Question 49

Which of the following mechanisms of effect is characteristic to anticoagulant rodenticides?

Answer 49

Block vitamin K epoxide reductase

Question 50

Which clinical signs are caused by butterfly toxins?

Answer 50

Coughing, sneezing

Question 51

Which disease results from acute poisoning by Solanum spp.?

Answer 51

Both  Gastric form  Nervous system type

Question 52

Which compound damaged selectively the cell membrane through the ion channel?

Answer 52

Organochlorine

Question 53

Which antibiotic is prohibited in hamsters?

Answer 53

``` Lincomycin Not prohibited:  Criprofloxacin  Enrofloxacin  Cephalexin ```

Question 54

Which is a clinical feature of NSAID toxicosis?

Answer 54

Both  Behavioural disturbances  Lung oedema

Question 55

What are the clinical signs of acute lidane toxicosis?

Answer 55

Excitation, aggressivity, convulsions

Question 56

Which of the following mechanisms of effect is characteristic to arsenic?

Answer 56

Binds to the sulfhydrid groups of proteins

Question 57

Which clinical signs are caused by Daffodil spp.?

Answer 57

Severe gastrointestinal and in high dose cardiovascular symptoms

Question 58

Which clinical signs are characteristic to urea poisoning?

Answer 58

Both  Excitation  Toddling movement, kicking to abdomen

Question 59

Which plant is known to interfere with bioavailability?

Answer 59

Sudan grass

Question 60

What is the mechanism of effect of carbamates?

Answer 60

Reversible inhibitors of Acetylcholine esterase

Question 61

Which species belong to the field containing mould fungi?

Answer 61

Fusarium spp.