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Bacteriology and Mycology > Pasteurella/Mannheimia/Riemerella > Flashcards

Pasteurella/Mannheimia/Riemerella Flashcards

(35 cards)

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1
Q

What is the habitat of Pasteurella?

A
  • Mucous membranes
  • P. multocida
    • ​Cattle, Pigs, Rabbits, Cats and Dogs
    • Normal animals - commensals
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2
Q

What is the habitat of Mannheimia?

A
  • Mucous membranes
  • M. haemolytica
    • Cattle and Sheep
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3
Q

How is Pasteruella Transmitted?

A
  • Direct contact
  • Inhalation
  • Animal bites
    • Cat bite abscesses
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4
Q

What is the Transmission of Mannheimia?

A
  • Direct contact
  • Inhalation
  • Ingestion
  • Animal bites
    • Cat bite abscesses
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5
Q

What is the distrribtion of Pastreurella?

A
  • World wide
  • Some P. multocida has limited geographical distribution
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6
Q

What is the distribution of Mannheimia?

A
  • world wide
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7
Q

What is the morphology of Pasteurella multocida?

A
  • Small, gray/white circular, mucoid, smooth or rough colonies
    • canine strains are usually rough
  • Gram negative Coccobacilli - often bipolar staining
  • Facultative
    • Can grow oxidatively
    • Can grow anaerobically
      • Obtain enerbgy by fermentative pathways with organic compound
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8
Q

What are the antigentic characteristics of Pasteurella multocida?

A
  • Capsular antigens - A, B, D, E, F
    • Carter’s system - based on capsular polysaccharide composition
    • Indirect Hemagglutintion test for humoral antibody responses
  • Somatic serotypes 1 - 16
    • LPS based
    • Gel diffusion test
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9
Q

What is the resistance and susceptibility of Pasteurella multocida?

A
  • Susceptible to common disifectants and many antimicrobial agents
  • Resistan strains are very common
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10
Q

What is special about Pasteurella multocida?

A
  • Gram negative but NO growth on MacConkey agar
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11
Q

What is pathogenicity?

A

capacity of an organism to produce disease

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12
Q

What is virulence?

A

Measure of the degree of pathogenicity

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13
Q

What are the Pathogenic Factors of Pasteurella multocida?

A
  • Endotoxin
  • Neuraminidase - invasion
  • Hyaluronidase (Serotype B) - invasion
  • Capsule - antiphagocytic
  • Adhesins (pili)
  • Siderophores
  • Iron-regulated OMPs
  • Stress - significant
  • Exotoxin - Type D serotypes​
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14
Q

What is the function of neuraminidase in P. multocida?

A
  • Splits N-acetyl-neuraminic acid (NANA) from glycoproteins and glycolipids.
    • presentin a wide variety of body tissues and fluids.
    • “reduces viscosity of mucus”
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15
Q

What does the Type D P. multocida exotoxin do?

A
  • Dermonecrotic
  • Ssociated with the necrosis fo the tirbinate bones in swine with atrophic rhiniits
  • Highly lethal to mice and chickens
  • MW 125000 - 160,000 daltons
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16
Q

What diseases does Pasteurella multocida cause in poultry?

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A
  • Fowl Cholera
    • Acute septicemic condition - kills birrds rapidly
    • Chronic in recovered birds
  • Serotypes:
    • A: 1, 3, 4, 7
17
Q

What disease does Pasteurella multocida cause in Rabbits?

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A
  • Snuffles
    • Upper Respiratory Tract Infection
      • leads to Septicemia, otitis, conjunctivitis
    • Bordetella bronchiseptica frequently isolated in conjunction
  • Serotypes
    • A:12 (80-90% of cases)
    • A:3 (10-20% of cases)
    • Atrophic rhinitis
18
Q

What Diseases does Pasteurella multocida cause in swine?

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A
  • Pneumonia
    • Primary or secondary infection to other bacterial or viral diseases
    • Secondary to enzootic pneumonia Mycoplasma spp
    • Serotype A:3
  • Atrophic Rhinitis
    • Associated with Bordatella bronchiseptica
    • Serotype D:3
19
Q

What Diseases does Pasteurella multocida cause in cattle?

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A
  • Hemorrhagic Septicemia
    • ​Septicemic form of pasteurellosis
    • Serotypes B:2 or E:2
  • Bovine Respiratory Disease Complex (Shipping Fever and pneumonia)
    • Involves various other infectious agents including viruses (IBR and PI3), Mannhaimia heamolytica, H. somni, Mycoplasma bovis, and stress
    • Serotype
  • Meningoencephalitis
  • Mastitis
  • Abortion
  • Serotype A:3 predominant
20
Q

What disease does Pasteurella multocida cause in Dog/Cats?

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A
  • Common inhabitant of the oral cavity
    • Coomonly found in infected animals bites
    • Cat bite abscesses
21
Q

What diseases does Pasteurella multocida cause in Humans?

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A
  • Wide variety of Syndromes
  • Pneumonia
  • Bronchitis
  • Empyema
  • sinusitis
  • pleurisy
  • arthritis
  • otitis
  • meningitis
  • peritonitis
  • UTI
22
Q

What is the nature of Pasteurella multocida infections?

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A
  • Suppurative and fibrinous inflammatory process
23
Q

How are Pasteurella mutocida infections prevented?

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A
  • Prevent Stress - especially in cattle
  • Treat early
  • Bacterins immunization
    • killed products
  • Vaccines - live
    • In drinking water - fowl cholera
24
Q

What disease is caused by Pasteurella gallinarum (Avibacterium gallinarum)?

Study These Flashcards
A
  • Fowl cholera-like disease
25
What disease is caused by *Pasteurella pneumotropica?*
* Pneumonitis in rodents
26
What disease does *Pasteurella caballi* cause?
* Respiratry diseases in horses
27
What disease does *Pasteurella aerogenes* cause?
* Gastroenteritis * Abortion * Diarrhea * pneumonia
28
What is the Morpholgy of *Mannheimia haemolytica?*
* Gram negative rod-shapped coccobacillus * Non-motile * Non-spore forming * Hemolytic * Colonies on MacConkey agar very tiny and brick red
29
What disease does *Bibersteinia trehalosi* cause?
* Respiratory disease in ruminants * similar to shipping fever
30
What are the antigenic Characterisitcs of *Mannheimia hamolytica?*
* 16 capsular serotypes - Indirect haemagglutination test to detect * Serotype 1 - Shipping fever * Serotype 2 - Nasal track of cattle
31
What is Seroconversion?
32
What are the pathogenic Mechanisms of *Mannheimia haemolytica?*
* Endotoxin * Neuroaminidae * Leukotoxin-cytotoxin-RTX toxin * Capsule * Siderophores * Adhesins (pili) * Iron-regulated OMPs * Stress is very important
33
What diseases does *Mannheimi haemolytica* cause?
* Bovine Respiratory Disease Complex (Shipping Fever) * Pneumonia * Goats, sheep, swine * Septicemia * Feeder / Nursing lambs * Respiratory Disease * Feeder lambs
34
How are *Manheimia haemolytica* infections controlled?
* Prevent Stress * Treatment - Antmicrobials * Immunize * Bacterins * Vaccines - live * Sub-unit vaccines * Toxoids
35
What is *Riemerella anatipestifer?*
* 21 Serotypes * Mortality 5 - 75% * Carrier birds are problems * Antimicrobials in drinking water * Vaccines - Live and killed * Causes: * "New duck disease" * Acute kidney disease of ducks and turkeys * Serofibrinous exudate * Air Sacculitis * Fibrinous pericarditis * Perihepatitis * Saphingitis * Meningitis * Septicemia

Bacteriology and Mycology (35 decks)

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