Path - Cells And Tests Flashcards Preview

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Flashcards in Path - Cells And Tests Deck (41):
1

red test tube cap

Glass=nothing
Plastic=clot activator

Serology
Blood bank
Chemistry tests

2

Red/gray test tube cap

No anticoagulant but does have clot activator gel for separating cells from serum

Serology
Chemistry tests

3

Light blue test tube cap

Citrate anticoagulant

Coagulation tests

4

Purple test tube cap

EDTA anticoagulant

CBC
Ammonia

5

Green test tube cap

Heparin anticoagulant

Blood gases
Chemistry tests

6

Gray test tube cap

Fluoride with oxalate anticoagulant

Glucose
Lactate

7

Yellow test tube cap

Acid citrate dextrose (ACD)
Blood bank studies

or
Sodium polyanethol sulfate (SPS)
Blood cultures

8

Dark blue test tube cap

Nothing
Stopper is usually specially treated

Trace elements
Nutritional studies
Toxicology

9

Sensitivity equation

100 X (TP/(TP+FN))

10

Specificity equation

100 X (TN/(TN+FP))

11

PPV equation

100 X (TP/(TP+FP))

12

NPV equation

100 X (TN/(TN+FN))

13

Number of existing cases of a disease in a population

Prevalence

14

Number of new cases of a disease in a population per unit time

Incidence

15

As prevalence increases, PPV ___

Increases

16

Screening tests require high ___

Confirmatory tests require high ___

Sensitivity

Specificity

17

More sensitive = more chance of ___

More specific = more chance of ___

FP


FN

18

True anemia is marked by what characteristic of RBCs?

Decreased RBC mass

19

Relative anemia is due to __

Causes?

Increased plasma volume


Pregnancy
Excessive hydration
Macroglobulinemia

20

Severe symptoms of anemia

Chest pain
Angina
Heart attack
Fainting

21

Trauma causes what kind of anemia?

Acute

22

What is the most common cause of anemia of insufficient production? Others?

Iron deficiency

B12 or Folate deficiency
bone marrow suppression or replacement
-parvovirus B19
-cancer

23

Hereditary membrane abnormality:

Elliptocytosis

24

Hereditary hemoglobin abnormality:

Thalassemia

25

Extravascular vs intravascular causes of RBC destruction

Extra-warm autoimmune hemolytic anemia
Intra-RBC fragmentation disorders

26

Large number of blue cells, which are immature RBCS, due to an increase in demand

Hyperproliferative

27

Definitions:
Variation in size of RBCs?
Shape?

Anisocytosis
Poikilocytosis

28

Anemia of chronic disease:
Morphologic characteristics

None

29

Thalassemia

quantitative defects of hemoglobin
Reduced globin chain synthesis
Alpha and beta

30

Beta thalassemia major
Characteristics

Severe microcytic hypochromic anemia
Anisocytosis
Poikilocytosis
Many uncleared RBCs
Polychromasia

31

Cytoskeletal abnormalities cause

Hereditary spherocytosis

32

Small nuclear remnants
Typically single
Normal in neonates

Howell Jolly bodies

33

Iron-containing mitochondrial remnants
Small clusters near cell periphery

Pappenheimer granules

34

MCV below normal
Above normal
Normal

Microcytic
Macrocytic
Normocytic


Mean cell volume

35

Most common cause of microcytic hypochromic cells

Iron deficiency

36

Cells in hemoglobin C disease

Target cells
Hemoglobin C crystals
Irregularly contracted cells
Spherocytes

37

Degmacyte vs schistocyte

Bite cell

Fragmented cell

38

Aggregates of denatured hemoglobin

Heinz bodies

39

Dacrocytes

Tear drop cells

40

Blue gray color of immature RBCs due to residual ribosomal material

Polychromasia

41

Aggregates of ribosomes
RNA
All over the cell

Basophilic stippling