Phys - Autonomics

Question 1

Curare

Answer 1

Antagonist for Nm receptors (N1)

Question 2

Atropine

Answer 2

Antagonist for M receptors

Question 3

Hexamethonium

Answer 3

Antagonist for Ng receptors (N2)

Question 4

Phentolamine

Answer 4

Antagonist for alpha receptors

Question 5

Propranolol

Answer 5

Antagonist for beta receptors

Question 6

Actions of M1 receptors

Answer 6

Some glands

Question 7

Actions of M2 receptors

Answer 7

Heart

Smooth muscle

Question 8

Actions of M3 receptors

Answer 8

Smooth muscle

Secretory glands

Question 9

Actions of alpha 1 receptors

Answer 9

Excitatory

Vasoconstriction
Ejaculation
Mydriasis
Thick saliva
Sphincter contraction

Question 10

Actions of alpha 2 receptors

Answer 10

Inhibitory

Decreased GI motility
Decreased GI secretions

Question 11

Actions of beta 1 receptors

Answer 11

• HR increase (chonotropic)
• Increased strength of heart contractions (inotropic)
• renin release (increase BP)

Question 12

Actions of beta 2 receptors

Answer 12

Relaxation of:

• GI
• Bronchiolar
• urinary bladder
• skeletal vessels

Question 13

Actions of beta 3 receptors

Answer 13

Lipolysis

Question 14

Which receptors are G coupled? What kind of coupling does each have?

Answer 14

qisss qiqiq

A1
A2
B1
B2
B3

M1-5

Question 15

Which receptors are cholinergic receptors? Where are they located? What neurotransmitter do they go with?

Answer 15

ACh

Nicotinic

• Ng: cell bodies of ALL postganglionic neurons (Sympathetic and Parasympathetic)
• Nm: motor end plates of skeletal muscle

Muscarinic (M1-5)
-effector organs in the Parasympathetic system

Question 16

Which receptors are adrenergic receptors? Where are they located? What neurotransmitter do they go with?

Answer 16

NE

Alpha and Beta
-effector organs and postganglionic axon terminals in the Sympathetic system

Question 17

Eccrine sweat glands use what neurotransmitter at the effector site? Which system are they part of?

Answer 17

ACh

Sympathetic

Question 18

NANC receptors

Answer 18

Non-adrenergic Non-cholinergic

Vasoactive intestinal peptide
Nitric Oxide
Substance P
Neuropeptide Y

Question 19

Craniosacral Nerves go with which system?

Which CN are important here?

Answer 19

Parasympathetic

III, VII, IX, X

Question 20

What main nerves are important for the Sympathetic system?

Answer 20

T1-L2

Thoracolumbar

Question 21

Anabolic
Conserves energy

Vs

Catabolic
Uses energy

Answer 21

Parasympathetic vs Sympathetic

Question 22

Actions of the Parasympathetic system

Answer 22

DEM BBLUESS

Defecation
Emesis (vomiting) 
Mitosis
Bradycardia
Bronchoconstriction
Lacrimation
Urination
Erection
Salivation
Secretion

Question 23

Organophosphate poisoning

Answer 23

Organophosphate is an AChE inhibitor

Results:
Too much ACh
Uncontrolled skeletal muscle contractions
Mimics parasympathetic activation (DEM BBLUESS)

Question 24

Radial muscles of the eye:
Receptor
Response
System

Answer 24

Alpha 1
Contraction, Mydriasis, dilation
Sympathetic

Question 25

Sphincter muscle of iris:
Receptor
Response
System

Answer 25

M
Contraction, miosis
Parasympathetic

Question 26

Ciliary muscles of the eye:
Receptor
Response
System

Answer 26

M
Contraction for near vision
Parasympathetic

Beta 2
Relaxation for far vision
Sympathetic

Question 27

Normal Pressure Hydrocephalus

Classic triad

Answer 27

Wet, wacky, wobbly

Urinary incontinence
Dementia
Gait disturbances

Question 28

Erection vs ejaculation

Systems

Answer 28

Point and shoot

Parasympathetic and Sympathetic

Question 29

Symptoms of Botulism

Toxin

Answer 29

Dozen Ds:
Dry mouth
Diplopia (double vision)
Dilated pupils
Droopy eyes
Diminished gag reflex
Dysphagia (difficulty swallowing)
Dysarthria (slurred speech)
Dysphonia (difficulty speaking)
Difficulty lifting head
Descending paralysis 
Dyspnea (difficulty breathing)