Phys - Autonomics Flashcards Preview

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Flashcards in Phys - Autonomics Deck (29):
1

Curare

Antagonist for Nm receptors (N1)

2

Atropine

Antagonist for M receptors

3

Hexamethonium

Antagonist for Ng receptors (N2)

4

Phentolamine

Antagonist for alpha receptors

5

Propranolol

Antagonist for beta receptors

6

Actions of M1 receptors

Some glands

7

Actions of M2 receptors

Heart
Smooth muscle

8

Actions of M3 receptors

Smooth muscle
Secretory glands

9

Actions of alpha 1 receptors

Excitatory

Vasoconstriction
Ejaculation
Mydriasis
Thick saliva
Sphincter contraction

10

Actions of alpha 2 receptors

Inhibitory

Decreased GI motility
Decreased GI secretions

11

Actions of beta 1 receptors

-HR increase (chonotropic)
-Increased strength of heart contractions (inotropic)
-renin release (increase BP)

12

Actions of beta 2 receptors

Relaxation of:
-GI
-Bronchiolar
-urinary bladder
-skeletal vessels

13

Actions of beta 3 receptors

Lipolysis

14

Which receptors are G coupled? What kind of coupling does each have?

qisss qiqiq

A1
A2
B1
B2
B3

M1-5

15

Which receptors are cholinergic receptors? Where are they located? What neurotransmitter do they go with?

ACh

Nicotinic
-Ng: cell bodies of ALL postganglionic neurons (Sympathetic and Parasympathetic)
-Nm: motor end plates of skeletal muscle

Muscarinic (M1-5)
-effector organs in the Parasympathetic system

16

Which receptors are adrenergic receptors? Where are they located? What neurotransmitter do they go with?

NE

Alpha and Beta
-effector organs and postganglionic axon terminals in the Sympathetic system

17

Eccrine sweat glands use what neurotransmitter at the effector site? Which system are they part of?

ACh

Sympathetic

18

NANC receptors

Non-adrenergic Non-cholinergic

Vasoactive intestinal peptide
Nitric Oxide
Substance P
Neuropeptide Y

19

Craniosacral Nerves go with which system?

Which CN are important here?

Parasympathetic

III, VII, IX, X

20

What main nerves are important for the Sympathetic system?

T1-L2

Thoracolumbar

21

Anabolic
Conserves energy

Vs

Catabolic
Uses energy

Parasympathetic vs Sympathetic

22

Actions of the Parasympathetic system

DEM BBLUESS

Defecation
Emesis (vomiting)
Mitosis
Bradycardia
Bronchoconstriction
Lacrimation
Urination
Erection
Salivation
Secretion

23

Organophosphate poisoning

Organophosphate is an AChE inhibitor

Results:
Too much ACh
Uncontrolled skeletal muscle contractions
Mimics parasympathetic activation (DEM BBLUESS)

24

Radial muscles of the eye:
Receptor
Response
System

Alpha 1
Contraction, Mydriasis, dilation
Sympathetic

25

Sphincter muscle of iris:
Receptor
Response
System

M
Contraction, miosis
Parasympathetic

26

Ciliary muscles of the eye:
Receptor
Response
System

M
Contraction for near vision
Parasympathetic

Beta 2
Relaxation for far vision
Sympathetic

27

Normal Pressure Hydrocephalus
Classic triad

Wet, wacky, wobbly

Urinary incontinence
Dementia
Gait disturbances

28

Erection vs ejaculation

Systems

Point and shoot

Parasympathetic and Sympathetic

29

Symptoms of Botulism
Toxin

Dozen Ds:
Dry mouth
Diplopia (double vision)
Dilated pupils
Droopy eyes
Diminished gag reflex
Dysphagia (difficulty swallowing)
Dysarthria (slurred speech)
Dysphonia (difficulty speaking)
Difficulty lifting head
Descending paralysis
Dyspnea (difficulty breathing)