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Flashcards in Path images Deck (99)
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1

Arteriosclerosis, Thrombosis

  • Aorta with large clot on L
    • thrombus= acellular
  • Atherosclerosis plaque on R
    • soft core of foamy macrophages, cholesterol clefts
  • cystic medial necrosis
    • fibrosis

2

Carotid artery: Arteriosclerosis, Thrombosis

medium (carotid) artery thrombus and surrounding atherosclerosis

cystic medial necrosis: foamy macros and cholesterol clefts

 

3

Heart: Acute Myocardial Infarction with Coagulation Necrosis

4

Coronary Artery Thrombosis

5

Heart, Acute Infarction

6

Heart, Ischemic Heart Disease

7

Heart, Mural Thrombus (thrombus in contact with the endocardial lining of a cardiac chamber)

8

Heart, Myocardial Hypertrophy

9

Heart, myocardial infarction, contraction band necrosis

10

Heart, Rheumatic Myocarditis

11

Kidney, Atheromatous Emboli

12

Kidney, diabetic glomoerulosclerosis and HTN

13

Kidney, hypertension

14

Kidney, Infarct (Coagulation Necrosis)

15

Lung and Heart, Septic Emboli

16

Polyarteritis Nodosa

17

Polyarteritis Nodosa

18

Skin, Glomangioma

19

Vascular pathology in hypertension. Hyaline
arteriolosclerosis. The arteriolar wall is thickened with
increased protein deposition (hyalinized), and the lumen is
markedly narrowed.

20

Hyperplastic arteriolosclerosis (onion-skinning;
arrow) causing luminal obliteration (arrow; periodic acid–
Schiff stain).

21

Gross kidney showing granular surface consistent
with nephrosclerosis due to chronic hypertension

22

Heart showing left ventricular hypertrophy.

23

Image of fundus showing hypertensive retinopathy
with blurring of the optic disc, exudates, flame hemorrhages
and nipping of venules at the arteriovenous crossings.

24

Aorta (micro, H+E, low power). Early atherosclerotic
plaque. 2 components can be seen: 1) fibrous cap consisting of
dense collagen and 2) soft central core. This section also shows
fresh thrombus material overlying the atherosclerotic plaque. In
this early lesion there are mild secondary changes in the media
(atrophy).

25

 This is a formalin-fixed abdominal
aorta with femoral vessels and attached kidneys showing moderate
atherosclerosis. The atherosclerosis typically is more severe in the
infrarenal portion and extends into the renal artery ostia and femoral
arteries. Note the sparing of the mesenteric vessels. The plaques are
somewhat raised and yellowish in color

26

 Abdominal aortic aneurysm: Opened view, with the
location of the rupture tract indicated by a probe. The wall of the
aneurysm is exceedingly thin, and the lumen is filled by a large
quantity of layered but largely unorganized thrombus

27

(A) Normal aorta (photomicrograph, elastic stain). With this special stain, elastic tissue appears black. Note the closely spaced elastic lamellae in the media.

(B & C) Aorta (photomicrograph, elastic stain) demonstrating changes of cystic medial necrosis.

(B) Note the small, irregular spaces between the elastic lamellae.

(C) Aorta at higher power showing more severe changes.

28

Image 1. Giant-cell (temporal) arteritis. Examination of the
temporal artery of a patient with giant-cell arteritis shows a
thickened, nodular, and tender segment of a vessel on the
surface of head (arrow).
Image 2. Giant-cell (temporal) arteritis. H&E stain of
section of temporal artery showing giant cells (arrow) at
the site of the internal elastic lamina in active arteritis.

29

Giant-cell (temporal) arteritis.
Elastic stain of temporal artery showing
disruption/degeneration of the internal elastic
lamina. (arrow).

30

Image 1. Hemangioma (Gross photograph)
Typically appear as a red, well-demarcated
papule on the skin. Compare to tan-brown
freckles.
Image 2. Hemangioma (Microscopic) Note the organized, lobular
architecture. Each lobule consists of small vessels (capillaries in this case)
lined by benign endothelial cells.