- Aorta with large clot on L
- thrombus= acellular
- Atherosclerosis plaque on R
- soft core of foamy macrophages, cholesterol clefts
- cystic medial necrosis
Carotid artery: Arteriosclerosis, Thrombosis
medium (carotid) artery thrombus and surrounding atherosclerosis
cystic medial necrosis: foamy macros and cholesterol clefts
Heart: Acute Myocardial Infarction with Coagulation Necrosis
Coronary Artery Thrombosis
Heart, Acute Infarction
Heart, Ischemic Heart Disease
Heart, Mural Thrombus (thrombus in contact with the endocardial lining of a cardiac chamber)
Heart, Myocardial Hypertrophy
Heart, myocardial infarction, contraction band necrosis
Heart, Rheumatic Myocarditis
Kidney, Atheromatous Emboli
Kidney, diabetic glomoerulosclerosis and HTN
Kidney, Infarct (Coagulation Necrosis)
Lung and Heart, Septic Emboli
Vascular pathology in hypertension. Hyaline
arteriolosclerosis. The arteriolar wall is thickened with
increased protein deposition (hyalinized), and the lumen is
Hyperplastic arteriolosclerosis (onion-skinning;
arrow) causing luminal obliteration (arrow; periodic acid–
Gross kidney showing granular surface consistent
with nephrosclerosis due to chronic hypertension
Heart showing left ventricular hypertrophy.
Image of fundus showing hypertensive retinopathy
with blurring of the optic disc, exudates, flame hemorrhages
and nipping of venules at the arteriovenous crossings.
Aorta (micro, H+E, low power). Early atherosclerotic
plaque. 2 components can be seen: 1) fibrous cap consisting of
dense collagen and 2) soft central core. This section also shows
fresh thrombus material overlying the atherosclerotic plaque. In
this early lesion there are mild secondary changes in the media
This is a formalin-fixed abdominal
aorta with femoral vessels and attached kidneys showing moderate
atherosclerosis. The atherosclerosis typically is more severe in the
infrarenal portion and extends into the renal artery ostia and femoral
arteries. Note the sparing of the mesenteric vessels. The plaques are
somewhat raised and yellowish in color
Abdominal aortic aneurysm: Opened view, with the
location of the rupture tract indicated by a probe. The wall of the
aneurysm is exceedingly thin, and the lumen is filled by a large
quantity of layered but largely unorganized thrombus
(A) Normal aorta (photomicrograph, elastic stain). With this special stain, elastic tissue appears black. Note the closely spaced elastic lamellae in the media.
(B & C) Aorta (photomicrograph, elastic stain) demonstrating changes of cystic medial necrosis.
(B) Note the small, irregular spaces between the elastic lamellae.
(C) Aorta at higher power showing more severe changes.
Image 1. Giant-cell (temporal) arteritis. Examination of the
temporal artery of a patient with giant-cell arteritis shows a
thickened, nodular, and tender segment of a vessel on the
surface of head (arrow).
Image 2. Giant-cell (temporal) arteritis. H&E stain of
section of temporal artery showing giant cells (arrow) at
the site of the internal elastic lamina in active arteritis.
Giant-cell (temporal) arteritis.
Elastic stain of temporal artery showing
disruption/degeneration of the internal elastic
Image 1. Hemangioma (Gross photograph)
Typically appear as a red, well-demarcated
papule on the skin. Compare to tan-brown
Image 2. Hemangioma (Microscopic) Note the organized, lobular
architecture. Each lobule consists of small vessels (capillaries in this case)
lined by benign endothelial cells.