Pathology Flashcards

(54 cards)

1
Q

what lines the auditory meatus and the external ear canal?

A

stratified squamous epithelium

continuous with skin

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2
Q

what does the dermis of the external ear canal contain?

A

hair follicles
sebaceous glands
ceruminous glands

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3
Q

what lines the middle ear?

A

columnar mucosa

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4
Q

what lines the nasal vestibule?

A

squamous epithelium

continuous with the skin

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5
Q

what type of gland are the salivary glands?

A

exocrine

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6
Q

what are the three major salivary glands?

A

parotid
submandibular
sublingual

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7
Q

what epithelium lines the ducts of the salivary glands?

A

columnar/cuboidal epithelium

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8
Q

what is otitis media?

A

inflammation of the middle ear

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9
Q

who most commonly gets otitis media?

A

children

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10
Q

what is the usual aetiology behind otitis media?

A

viral

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11
Q

what are some more common causes of acute bacterial otitis media?

A

strep pneumoniae
h influenzae
moraxella catarrhalis

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12
Q

what are some possible causes of chronic otitis media?

A

pseudomonas aeruginosa
staph aureus
fungi

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13
Q

what causes acquired cholesteatoma?

A

chronic otitis media and a perforated tympanic membrane

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14
Q

what causes congenital cholesteatoma?

A

proliferation of embryonic rest

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15
Q

what can be seen in the ear in cholesteatoma?

A

a pearly white mass in the middle ear

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16
Q

what is seen on histology of cholesteatoma?

A

squamous epithelium
abundant keratin production
associated inflammation

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17
Q

what is the most common type of ENT tumour?

A

squamous cell carcinomas

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18
Q

what is vestibular schwannoma?

A

tumour of the vestibular portion of CN VIII

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19
Q

where is a vestibular schwannoma found?

A

within the temporal bone

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20
Q

if a young patient has bilateral vestibular schwannoma what should be considered?

A

neurofibromatosis type 2

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21
Q

what causes vestibular schwannoma?

A

unknown
often sporadic
may be linked to loud noise exposure

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22
Q

what are the two growth patterns seen in vestibular schwannoma?

A

antoni A

antoni B

23
Q

what is another name for allergic rhinitis?

24
Q

who are nasal polyps not commonly seen in?

25
if a young person has nasal polyps, what should be considered?
cystic fibrosis
26
what epithelium lines nasal polyps?
respiratory or squamous epithelium
27
what is GPA?
an autoimmune disorder of unknown cause
28
what characterises GPA?
small vessel vasculitis and necrosis, usually limited to the resp tract and kidneys
29
what age group gets GPA/
>40's
30
how does GPA preent?
respiratory symptoms renal disease nasal symptoms
31
what antibody is seen in GPA?
ANCA (anti-neutrophil cytoplasmic antibody)
32
if cANCA is seen, what vasculitis is it?
GPA
33
if pANCA is seen, what vasculitis is it?
microscopic polyangiitis
34
what are three possible benign nasal tumours?
squamous cell papilloma sinonasal papilloma angiofibroma
35
what are five possible malignant nasal tumours?
``` SCC adenocarcinoma nasopharyngeal carcinoma neuroblastoma lymphoma ```
36
what are the three types of sinonasal papilloma?
inverted exophytic oncocytic
37
who usually gets sinonasal papilloma?
over 50's | more common in males
38
what are two risk factors for sinonasal papilloma?
HPV | organic solvents
39
how does sinonasal papilloma present?
blocked nose
40
where do inverted and oncocytic sinonasal papillomas affect?
the lateral walls of the nose and the paranasal sinuses
41
where do exophytic sinonasal papillomas affect?
the nasal septum
42
who is more commonly affected by nasopharyngeal carcinoma?
males | more common in the middle east
43
what are two strong risk factors for nasopharyngeal carcinoma?
EBV | volatile nitrosamines in food
44
what are the three types of nasopharyngeal carcinoma?
keratinising non keratinising baseloid
45
what causes a laryngeal polyp or nodule?
a reactive change in the laryngeal mucosa secondary to trauma (vocal abuse, infection, smoking)
46
what are laryngeal polyps and nodules rarely associated with?
hypothyroidism
47
what is a contact ulcer?
a benign response to injury on the posterior vocal cord
48
name four examples of things that can cause a contact ulcer
chronic throat clearing vocal abuse GORD intubation
49
what are the two peaks of incidence of laryngeal squamous cell papilloma?
<5 | 20-40
50
what is laryngeal squamous cell papilloma related to?
HPV types 6 and 11
51
what is a paraganglioma?
a tumour arising form clusters of neuroendocrine cells in the body
52
what is sialolithiasis?
stones in the salivary gland
53
what is the most common site for a salivary gland tumour?
parotid gland
54
what is the most common salivary gland tumour?
pleomorphic adenoma