Flashcards in Pathology of the mouth/esophagus Deck (33):
1
What are the 3 Ms of a pathological HSV specimen/
1. Multinucleation
2. Margination of the nucleus
3. Molding of the nucleus
2
What cells does HSV infect?
epithelial cells
3
What are the features of cytomegalovirus?
Owl-eye appearance
4
What types of cells does CMV infect?
endothelial and mesenchymal cells
5
What does mucormycosis look like?
ONLY broad bulbous hyphal forms that are at 90 degree angles
6
Pyogenic granuloma
Benign lobular capillary hemangioma
7
Aphthous ulcer
self-resolution. Canker sore
8
Leukoplakia
A white, hard, firm plaque. We worry that this will turn malignant.
9
Hairy leukoplakia: benign or malignant? What is it associated with?
Benign. Seen in HIV pts assoc'd with EBV infection.
10
What will you see on a hairy leukoplakia specimen?
hyperkeratosis, balloon cells, and acanthosis
11
Erythroplakia
Pre-malignant
12
What is squamous cell carcinoma assoc'd with?
smoking, alcohol, and HPV
13
In which salivary glands are neoplasms most likely to be malignant?
sublingual
14
What are two types of benign salivary gland tumors?
pleomorphic adenoma
warthin tumor
15
What are three types of malignant salivary gland tumors?
mucoepidermoid carcinoma
Acinic cell carcinoma
Adenoid cystic carcinoma
16
What types of cells do you see in a pleomorphic adenoma? Where are they most commonly found?
epitheial and myoepithelial. Found in the parotid gland
17
What are you worried about with a pleomorphic adenoma of the salivary gland?
Malignant transformation has a poor prognosis
18
Where would you find a warthin tumor?
parotid
19
What are the two components of a warthin tumor?
epithelial and lymphoid
20
What is the most common malignant tumor of the salivary gland?
Mucoepidermoid carcinoma
21
What are the two types of cells in a mucoepidermoid malignant tumor?
mucus secreting and squamous
22
What is a typical finding in a adenoid cystic carcinoma?
Perineural invasions
23
Which of these salivary neoplasms has the best survival?
Mucoepidermoid
24
In what conditions would you see an esophageal web?
Plummer vinson syndrome. Usually in women over 40
25
What are the components of plummer vinson syndrome?
1. Web
2. Anemia
3. Gossitis
4. Cheilosis
5. Upper esophagus carcinoma
26
What is a mallory-Weiss tear? How would it present?
Laceration at the GEJ. Will see forceful vomiting
27
What is Boerhaave syndrome?
Esophageal rupture. Catastrophic
28
In which patients would you see esophageal varices?
cirrhotic pts (90%!)
29
What are the two types of esophageal carcinoma?
Squamous cell carcinoma and adenocarcinoma
30
What kind of carcinoma does Barrett's esophagus give rise to?
adenocarcinoma
31
What are the criteria for Barrett's esophagus?
1. Endoscopic evidence of columnar epithelium
2. Intestinal metaplasia (goblet cells)
-->The presence of goblet cells defines barrett esophagus
32
How do you treat a platient with BE?
Routine surveillance and biopsy.
33