Peds obstructive disorders, tieman 12/9 Flashcards Preview

Year2 GI Exam II > Peds obstructive disorders, tieman 12/9 > Flashcards

Flashcards in Peds obstructive disorders, tieman 12/9 Deck (17):
1

definition cholestasis

systemic retntion biliary constituents as result failure to form or flow bile

2

intrahepatic cholestasis lab results

elevated transaminases and unconj bili

3

what can cause intrahepatic cholestasis

failure of formation of bile in hepatocyte or obstructive process confined to intrahepatic bile duct

4

extrahepatic cholestasis

obstructive process of extrahepatic bile ducts

5

lab results with extrahepatic cholestasis

elevated AP, GGTP, conj bili

6

what is neonatal obstructive jaundice

any newborn presenting or persisting after 14 days

7

lab results of neonatal obstructive jaundice

elevated conj bili, AP, GGTP
acholic stools sometimes

8

most common causes neonatal obstructive jaundice

biliary atresia
less common: congenital biliary tract anomalies, choledochal cysts and infections

9

biliary atrestia

post natal destruction of EH bile bile ducts with resultant injury and fibrosis of IH bile ducts

10

what are associations with biliary atresia

extrahepatic anomalies
most common cause hepatic death and reason for liver transplantation in children
F>M

11

how is biliary atresia Dx

lab, US, MRC and liver bx

12

Tx biliary atresia

porto-enterostomy
better if done at <60 days age

13

what disease has choledochal cysts

type V intrahepatic
Caroli's disease

14

majority choledochal cysts are found at what age

<10 y.o

15

presentation choledochal cysts

obstructive jaundice, acholic stools, pruritis, abd pain, and/or fever

16

Dx choledochal cysts

obstructive jaundice presentation
need US, MRCO and eRCP

17

Tx choledochal cysts and why

surgically resected because increase risk malignancy and cholangitis