drugs for GI infections I Flashcards Preview

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Flashcards in drugs for GI infections I Deck (45)
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1

What are the fluoroquinolones

Ciprofloxacin
Levofloxacin

2

what are the antiprotozoals

metronidazole

3

what other antibiotics are available for GI infections

vancomycin, bactrim (trimethoprim-sulfamethoxazole

4

definition of diarrhea
acure, persisten chronic

>3 unformed stools/day
acute 30 days

5

what viruses cause diarrhea

noro and rota

6

what bacteria cause diarrhea

salmonella, campylobacter, shigella, EHEC, vibrio, yersinia, EAEC, ETEC

7

what protozoa can cause diarrhea

cryptosporidium, giardia, cyclospora, entamoeba, others

8

what pathogens can cause dysentery

shigella, salmonella, campylobacter, EHEC, yersinia and C difficile

9

what do you test for with bloody diarrhea and no fever or HUS

shiga toxin and EHEC

10

bloody diarrhea with recent immigration from tropical Africa, Asia or Latin Aerica

entamoeba histolytica

11

what bloody diarrhea is assoc with shellfish

vibrio

12

general approach to Tx of infectious diarrhea

prevention dehydration

13

Tx protocol for mild-moderate dehydration

oral rehydration therapy, superior to administratino of IV fluids

14

necesary compounds in oral rehydration therapy

carbs (glucose), Na, K, cl and water

15

Indiscriminant se of antimicrobials leads to increased risk of

antimicrobial Resistance, prolonged shedding of certain pathogens, Salmonella, C difficile
Side effects
superinfection after destruction of normal flora

16

what is rec antibiotic for mild to moderate travelers diarrhea

loperamide of bismuth subsalicylate alone

17

if travelers diarrhea is associated with fever or bloody stools, self tx with what antibiotics for how long

any of the floxacins for 3 days

18

what drug is used to tx noninvasive strains of E coli

rifaximin

19

what is Tx for quinolone R campylobacter

azithromycin

20

what antibiiotic use is assoc with C difficile

clindamycin, ampicilin, cephalosporins, fluoroquinolones, PPIs

21

hish risk groups C diff

elderly, debilitated, cancer, surgical

22

Tx options for C diff

metronidazole (PO or IV), vancomycin PO, fidazomicin

23

Vancomycin is preffered for when in C diff

severe infection
otherwise use metronidazole

24

how is vanco administered

PO

25

Tx campylobacteriosis

erythromcyin

26

if Diarrhea lasts longer than 7-10 days, most likley?

parasitic, giardia

27

Tx giardia

metronidazole

28

when is antibiotic Tx not recommended for diarrhea

EHEC, salmonella

29

why do not use antibiotics with salmonella

increase fecal shedding of pathogens and associated with prolonged carriage and relapse, does not reduce diarrhea

30

MOA idoquinol antiprotozoal

unknown, only effective on luminal organisms