Pentose Phosphate Pathway Flashcards Preview

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Flashcards in Pentose Phosphate Pathway Deck (7)
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1

What cells undergo the Pentose Phosphate Pathway

Biosynthetically active tissue cells

- primarily liver, adipose cells, mammary glands and erythrocytes

- no ATP is directly used

2

Irreversible enzymes/reactions of PPP

-Glucose 6-P Dehydrogenase

Glucose 6-P -> 6-P Gluconolactone

- 6-P Gluconate Dehydrogenase

6-P Gluconate -> Ribulose 5-P


* Both produce NADPH*

3

Net products of PPP

Ribulose 5-P

2 NADPH

2H+

CO2

4

Committed, rate-limiting step of The PPP

G 6-P DHase oxidizing glucose 6-phosphate to 6-P gluconolactone

- 1st step of PPP

5

Reversible steps of PPP

Carbon-shuffling steps

6

Oxidative reactions of PPP

G6P is converted to 6-P Glucolactone -> 6-P Gluconate -> Ribose 5-P

* Only done is NADPH is required, produces 2 NADPH*

7

Ribulose 5P can carbon switch into what molecules

F6P and GA-3P

Conducts glycolysis