Pharm Ch 1 Flashcards

(38 cards)

1
Q

What are Aerosolized agents?

A

Group of aerosolized drugs that are instilled directly intro the trachea.

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2
Q

What are the categories of aerosolized drugs?

7 types

A
  • adrenergic
  • anti-cholenergic
  • anti-asthmatic
  • mucoactive
  • corticosteroid
  • anti-infective
  • surfactant
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3
Q

What is airway resistance?

A

Measure of airway impedance

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4
Q

What is a brand name or trade name of a drug?

A

It’s a proprietary name given by the manufacturer.

Brand name and trade name are the same.

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5
Q

Chemical name?

A

Name derived form chemical structure.

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6
Q

COPD?

A

Chronic obstructive pulmonary disorder.

  • airflow limitation that is not fully reversible and progressive.
  • associated with abnormal inflammatory response of the lung.
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7
Q

Code name of a drug?

A

Name assigned by A manufacture to an experimental chemical that could be a new drug.

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8
Q

Drug administration?

A

Method by which a drug is made available to the body.

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9
Q

Generic name of a drug?

A

Name assigned to a chemical by U.S. Adopted name council when it shows to have therapeutic use and the drug company want to sell it.

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10
Q

Non-proprietary name of a drug?

A

Name of the drug other than it’s tradename.

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11
Q

Official name of the drug?

A
  • after the drug is fully approved for use and entered into the national formulary.
  • the drug’s generic name becomes official name.
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12
Q

Orphan drugs?

2 reasons of importance

A

Drug or biological products for the diagnosis or treatment of a rare disease

  • affecting fewer than 200,000 people
  • with no reasonable expectation of recovering cost of drug development but treats specific disease
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13
Q

Pharmacodynamics?

A

Dynamic is the drug on the body

dynamic DOB

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14
Q

Pharmacogenetics?

A

Study of the interrelationships between drugs and genetic differences

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15
Q

Pharmacokinetics?

A

Kinetic BOD

The effect of the body on the drugs

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16
Q

Pharmacology?

A

Study of drugs

17
Q

Therapeutics?

A

Art of treating disease with drugs

18
Q

What is phase 1 new drug approval?

A

Drug is administered and researched on a small group of a healthy volunteers

19
Q

What is phase 2 new drug approval

A

Drug is investigated and administered to a small number of individuals with the disease

20
Q

What is phase 3 new drug approval

A

Drug is administered to a large number of individuals with the disease. Multi center studies

21
Q

What are over-the-counter drugs?

A
  • drugs that have strength less than prescription formulation.
  • yet still can have a hazardous affects if taken haphazardly
22
Q

Why would you choose genetic over brand-name prescriptions?

A
  • Cost associated with brand-name drug marketing.

- brand-name invested more money then generic brand name company

23
Q

What are anti-infective agents

A

Antibiotics or antituberculosis drugs

24
Q

What is an example of neuromuscular blocking agent?

A

Chariform agents

25
What is an example of CNS agents?
Analgesics and sedatives
26
What is an example of antiarrhythmic agents?
Cardiac glycosides and lidocaine
27
What are antihypertensive and Anti-anginal agents.
Beta blocking or nitroglycerin
28
What are examples of anticoagulant or Thrombolytic agents
Heparin or streptokinase
29
What are example of diuretics
Thiazides or furosemide
30
What are the purpose of beta adrenergic agents?
Relaxation the bronchial smooth muscle and bronchodilation. - COPD - asthma - CF - acute bronchitis
31
What are alpha-adrenergic agents used for? | -what do they treat?
Topical vasoconstriction and de-congestion | - treats upper airway swelling
32
What do anticholenergic agents do? | What do they treat?
Relaxation of cholinergic induced bronchoconstriction | -improve ventilation flow for COPD and asthma
33
What do mucoactive agents do? | 2 points
- Changes properties of mucus in the airway. | - Reduces viscocity and promotion of clearance
34
What do corticosteroids treat?
Reduction in control of airway inflammation response associated with asthma or seasonal chronic rhinitis.
35
What are antiasthmatic agents used for?
Prevention of onset and development of asthmatic response through inhibition of airway inflammation
36
What are exogenous surfactants used for?
Normalizing lung compliance for newborns in distress. | Surface tension
37
What are prostacyclin analogues used for?
Treats pulmonary hypertension | -decreases shortness of breath and increasing walking distance
38
What is ARDS?
Respiratory insufficiency as a result of: - trauma - pneumonia - O2 toxicity - gram neg sepsis - systemic inflammatory response