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Flashcards in Chapter 3 Pharm Deck (18)
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1

What a cascade impactor?

Device that uses multiple steps to determine size of aerosol particles

2

What are CFCs?
What are they used for?

Chlorofluorocarbons.
-for propellants in mdi

3

What is a dead volume?

Amount of solution that remains in the reservoir of a small volume nebulizer

4

What is deposition?

Process of particles depositing out of suspension to remain in lung

5

What is heterodisperse

Refers to the size of particles in aerosol. Particles having different sizes

6

What is Hydrofluoroalkane?

Nontoxic liquified gas propellant use to administer medication

7

What is in vitro?

Tested in a lab

8

What is in vivo?

Testing done on animals or humans

9

What is monodisperse

In reference to the size of particles in Aerosol, all of them the same size

10

What is poly disperse?

In reference to the size of aerosol particles, meaning many different particle sizes

11

What is a reservoir device?

Global term describing referring to extension to an MDI

12

What is a spacer

Simple tube device with no one-way valves to contain aerosol cloud

13

What is stability?

Describing the tendency of aerosol particles to remain in suspension

14

What is a MMAD size?

Mass median aerodynamic diameter

15

What are advantages of aerosolized drug admin?
6 reasons

-smaller doses
-rapid onset
-localized effect
-smaller side effects
-relatively painless
-lung provides portal to body intended for systemic effects

16

What are the disadvantages to aerosolized meds?
6 reasons

-variables can effect dosages
-inconsistent dose reproducibility
-patients can have difficulty with coordination
-lack of knowledge for nurses and doctor
-standardized technical info is lacking
-multiple device types can be confusing to patients and staff

17

What is fine particle fraction or dose?

The size the particle should be for the best chance of reaching the lower respiratory tract.

18

What is an aerosol?

Suspension of liquid or solid particles .001 to 100 micro meters in a gas