*Pharmacology 4 (lecture 4) - only partially finished Flashcards Preview

Study Notes - Cardiology > *Pharmacology 4 (lecture 4) - only partially finished > Flashcards

Flashcards in *Pharmacology 4 (lecture 4) - only partially finished Deck (31):
1

What drugs can be used to treat hypertension? (6)

Alpha blockers
ACEI
ARB
Beta blockers
Calcium channel antagonists
Thiazide like diuretic

2

What do all beta blockers end in?

-olol

3

What do ACEI end in?

-pril

4

What do all ARB end in?

-artan

5

What drugs can be used to treat angina? (6)

Beta blockers
Calcium antagonists
Nitrates
Nicorandil
Ivabradine
Ranolazine

6

What are the 3 categories of anti-thrombotic drugs?

Anti-Platelet drugs
Anti-coagulants
Fibrinolytics

7

What are 4 examples of anti-platlet drugs?

Aspirin
Clopidogrel
Prasugrel
Ticagrelor

8

What are 3 examples of anti-coagulant drugs?

Warfarin
Rivaroxaban
Dabigatran

9

What are 2 examples of fibrinolytic drugs?

Streptokinase
Tissue Plasminogen activator (tPA)

10

What are 2 groups of anti-cholesterol drugs?

Statins
Fibrates

11

What are the 5 main groups of CV drugs?

Anti-hypertensives
Anti-anginals
Anti-thrombotic
Anti-cholesterol
Anti-arrhythmics
(+others)

12

How do diuretics work?

They block Na reabsorption in the kidneys and reduce the amount of fluid in the body

13

What are the 2 categories of diuretics?

Thiazide like diuretics (mild)
Loop diuretics (stronger)

14

Example of a thiazide like diuretic?
Used to treat?

Bendrofluazide
Hypertension

15

Example of a loop diuretic?
Used to treat?

Furosemide
Heart failure

16

Side effects of diuretics? (4)

Hypokalaemia (tired, arrhythmias)
Hyperglycaemia
Increased uric acid = gout
Impotence

17

How do beta blockers work?

They block beta 1 +/- beta 2 adrenoceptors

18

What is an example of a cardioselective beta blocker?
What is this used to treat? (3)

Atenolol
Angina
Hypertension
Heart failure

19

What is an example of a non selective beta blocker?
What is it used to treat?

Propranolol
Thyrotoxicosis

20

Contra-indication for use of beta blocker?

Asthma

21

Side effects of beta blockers?

Asthma
Tiredness
Heart failure (good in the long term but can worsen it in the short term)
Cold peripheries

22

2 types of calcium antagonists?

Dihydropyridines
Rate limiting calcium antagonists

23

Example of a dihydropyridine?
What is used to treat? (2)
Side effects?

Amlodipine
Hypertension and angina
Ankle oedema

24

2 examples of rate limiting calcium antagonists?
What are they used to treat?
What should these never be used with?

Verapamil, Dilitiazem
Hypertension, angina, SV arrhythmias
Beta blockers

25

How do alpha blockers work?

Block alpha adrenoceptos to cause vasodialtion

26

What are alpha blockers used to treat?

hypertension
Prostatic hypertrophy

27

Example of alpha blocker?
Side effects?

Doxazosin
Postural hypotension

28

How do ACEI work?

Block angiotensin I from becoming angiotensin II

29

Example of an ACEI?

Lisinopril

30

What are ACEI used for?

Hypertension and heart failure

31

In terms of the kidneys what is ACEI good and bad for?

Good for diabetic nephropathy
Bad for renal artery stenosis