Pharmacology of Anticoagulation Therapy Flashcards Preview

Unit 4: Blood and Lymph > Pharmacology of Anticoagulation Therapy > Flashcards

Flashcards in Pharmacology of Anticoagulation Therapy Deck (7)
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1

What is hemostasis?

the process of clot formation to repair damaged vasculature

2

What conditions predispose to clot formation?

1. atherosclerosis
2. DVT from bed rest, surgery, pregnancy, age, air travel
3. A-fib (blood pools in the atrium)

3

What are the 3 forms of heparin?

1. unfractionated heparin
2. low molecular weight heparins (LMWH)
3. Fondaparinux (Arixtra)

4

How do the heparins/oral anticoagulants work?

they interfere with the coagulation cascade and the formation of thrombin

5

What does thrombin do?

it cleaves fibrinogen into fibrin

6

What are fibrinolytic agents?

they breakdown clots by increasing plasmin levels

7

What are antiplatelet agents?

they block activation of platelets