Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MED 1022 Wks 7-12 > physiology > Flashcards

physiology Flashcards

1
Q

main thing driving blood flow is

A

pressure
main thing driving pressure is
volume and distensibiltiu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

pulse pressure

A

systolic pressure - diastolic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Mean arterial pressure MAP

A

diastolic + 1/3 pulse pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

hypertension

A

greater than or equal to 90 mmHg for diastolic

greater than or equal to 140 mmHg for systolic

can have either or both of these in hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

arteries -key properties

A

elastic

large diameter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

resistance in arteries vs arterioles

A 
arteries= big diameter=little resistance
arterioles= small diameter=heaps of resistance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

active hyperaemia

A

\wen u e.g. run= increase metabolic activity of tissue= local chemical changes =causing vasodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

reactive hyperamei

A

block and then due to physical n chemical changes, get vasodilaiton n massive blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

auto regulation of blood flow

A

increased stretch= increased contraction (constriction)

decreased stretch= decreased contraction (dilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

prostacylcin PGI2

A

vasodilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

EDHF

A

vasodilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

endothelial stimulation to get it to vasodilate or vasoconrtstict:

A

sheer stress of blood flow
laminar flow=vasodilation
turbulent flow= reduced release of vasodialtion
• blood borne factors n subs released from platelets
• Ach , used as a tool –ie used in clinical

bifurication=turbulent flow= blood clot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

coronary angiography

for Ach

A

for Ach
if get vasodilation= endo is healthy
if get vasoconstriction= endo is impaired

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

coronary angiography

for NTG

A

for NTG
this is any endothelium-independent vasodilator, so inserting it would be testing function of the smooth muscle
if get vasodilation=smooth musucle fine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

NO

A

vasodilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

veins cos stretchy

A

big change in volume=small change in pressure

17
Q

sympathetic effect on veins

A 
increased sympa stim on veins
contract muslces
makes walls stiff
less stretchy/distensible
increase venous pressure
18
Q

things that affect venous return

A
  1. venous pressure=increase pressure=increase venous return
  2. skeletal muscle pump
  3. resp pump
19
Q

varicose vein

A

faulty valves

20
Q

vascular function

A

AS U INCREASE RIGHT ATRIAL PRESSURE, YOU DECREASE VENOUS RETURN

21
Q

the cardiac function

A

u increase right atrial pressure, U INCREASE END-DIASTOLIC VOLUME AND SO THEREFORE U INCREASE STROKE VOLUME

22
Q

response to haemorrhage

A

vasoconstriction
vasodilation\

take home message-fall in cardiac output is due to fall in venous return

23
Q

Mean Systemic (or circulatory) Filling Pressure (Psf)

A

pressure everywhere once u’ve stopped your heart

determined mainly by volume of blood and pressure in veins

24
Q

CO determined by

A

venous return

25
Q

MAP

A

CO x TPR

26
Q

cardiovascular system as a control system

A 
baroreceptors
sensory affernt nerves
medullary cardiovascular centre
efferent nerves
heart, arterioles, veins
27
Q

baroreceptors

A

carotid sinus,arch of aorta

28
Q

baroreceptor reflex

A

increase in pressure
stretches aorta n carotids
baro increase firing
send message to brain
brain send para message back to heart telling it to slow HR
n decrease sympa message to vessels =vasodilaite=decrease pressure

incrase para
decrease sympa

SHORT TERM REGULATION
cos get adaptation

29
Q

long term control of MAP is

A

renin system

• Pressure Diuresis/Natriuresis

30
Q

RAA system

A

wen MAP falls, blood flow falls
• Renin released into circulation from juxtaglomerular cells in the kidneys
• This plasma renin converts angiotensin(from liver) to angiotensin 1
• Angiotensin 1 then converted to angiotensin 2 via angiotensin-converting enzyme
• Angiotensin 2 causes vessels to constrict, leading to increased blood pressure
• Angiotensin 2 also stimulates secretion of aldosterone from adrenal cortex. Aldosterone tells kidney to increase reabsorption of sodium n water into blood=increase blood pressure as well

31
Q

stroke volume

A

edv-esv

32
Q

75%

A

• 75% of the Ca for cardiac contraction comes from the sarcoplasmic reticulum
• 25% comes from ECF – exam question
– Cardiac muscle cell placed in solution with no calcium won’t contract.

33
Q

cardiac output

A

volume of blood ejected per min

34
Q

SA action potential

A

NA n Ca constantly leaking in

no fast voltage sensitive Na channel

Ca channel open, upward positiveness
K channel open- downwards

35
Q

tetrodotoxin

A

blocks fast voltage sensitive Na channel

36
Q

to increase filtration (pushing fluid out of capillaries)

A

dilate arterioles
increase systemic arterial pressure
increase venous pressure

37
Q

to increase reabsorption (pulling fluid back into capillaries)

A

constrict arterioles
decrease systemic arterial pressure
decrease venous pressure

MED 1022 Wks 7-12 (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions