Physiology in Pregnancy Flashcards

1
Q

What breast changes are seen in pregnancy?

A

Increased size, vascularity (warmer, tender)
Increased nipple pigmentation
Montgomery tubercules appear on areola
Colostrom at 3months

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2
Q

What Cardiovascular changes are seen in pregnancy?

A
50-70% increased circulating volume
Vascular resistance falls 20-32 weeks
Increased blood flow/CO/SV
Increased Heart rate
Decreased cardiac output in supine position
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3
Q

How do you resuscitate pregnant women?

A

NEVER ON BACK
Left lateral tilt
Elevate patients side

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4
Q

Cardiovascular changes during childbirth?

A

Autotransfusions of contractions
Pain - circulating catecholamines
10% increase in CO

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5
Q

How does cardiac output increase post delivery?

A

Increased by 80% for 1hr

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6
Q

What are the postpartum cardiovascular changes?

A
Return to normal by 3 months
BP falls then returns to normal at 6 weeks post
SVR increase 
over first 2 weeks
CO continues to fall over next 24 weeks
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7
Q

What respiratory changes are seen in pregnancy?

A
20% increase in O2 demand
40-50% increase in ventilation
Increased RR/TV
Decreased residual capacity
PEFR + FEV1 unchanged
Decreased PCO2
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8
Q

What renal changes are seen in pregnancy?

A
Dilation of urinary collecting system
60-80% increased renal plasma flow
GFR increases by up to 50%
Protein excretion increased
Microscopic haematuria
Glycosuria common 
Increased Urates
Decreased Urea, Creatinine
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9
Q

What haematological changes are seen in pregnancy?

A
Plasma volume increased
Decreased Hg, Hcrit, RCC
Decreased platelets
2-3x increased iron requirements
10-20 increased folate requirements
WCC increases
Hypercoagulable state
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10
Q

How does Hg change in pregnancy?

A

Decreased

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11
Q

How does WCC change in pregnancy?

A

Increased

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12
Q

How does platelets change in pregnancy?

A

Decreased/normal

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13
Q

How does CRP change in pregnancy?

A

no change

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14
Q

How does ESR change in pregnancy?

A

Increased

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15
Q

How does Urea change in pregnancy?

A

Decreased

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16
Q

How does Creatinine change in pregnancy?

A

Decreased

17
Q

How does Urates change in pregnancy?

A

Decreased (increases with gestational age)

18
Q

How does 24hr protein change in pregnancy?

A

Increased

19
Q

How does total protein change in pregnancy?

A

Decreased

20
Q

How does albumin change in pregnancy?

A

Decreased

21
Q

How does AST/ALT/GGT change in pregnancy?

A

Decreased or normal

22
Q

How does alk phos change in pregnancy?

A

Huge Increase

23
Q

How does bile acids change in pregnancy?

A

No change

24
Q

How does D dimer change in pregnancy?

A

Increased