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Flashcards in Physiology-Renal Checkpoint Quiz Deck (19):
0

Specialized cells of the thick ascending loop of henle or distal tubule adherent to every glomerulus at site between afferent and efferent arterioles that regulate glomerular filtration are called

Macula densa cells

1

Which of the following layers of the glomerular capillary membrane restrict solute movement by both size and charge selectivity?
-endothelium
-basement membrane
-epithelial
-podocyte

Basement membrane

2

Which of the following serves as primary means for physiologic regulation of glomerular filtration rate?
-glomerular capillary filtration coefficient
-glomerular hydrostatic pressure
-hydrostatic pressure in bowman's capsule
-colloid osmotic pressure of glomerular capillary plasma proteins
-colloid osmotic pressure of proteins in bowman's capsule

Glomerular hydrostatic pressure

3

Constriction of afferent arteriole would result in what change to GFR
-increase in GFR
-decrease n GFR
-depends on degree of dilation
-no change

Decrease in GFR

4

A reduction in the delivery of NaCl to macula densa would result in which of he following?
-efferent arteriole dilation with decrease in GFR to normal
-efferent arteriole constriction with an increase in GFR to normal
-afferent arteriole dilation with an increase in GFR to normal
-afferent arteriole constriction with decrease in GFR to normal

Afferent arteriole dilation with increase in GFR to normal

5

Angiotensin II causes which of the following in order to normalize GFR in states of decreased RBF?
-efferent arteriole dilation with decrease in GFR to normal
-efferent arteriole constriction with increase in GFR to normal
-afferent arteriole dilation with increase in GFR to normal
-afferent arteriole constriction with decrease in GFR to normal

Efferent arteriole constriction with increase in GFR to normal

6

Which of the following is not reabsorbed in the proximal tubule?
-Na
-HCO3
-glucose
-H

H

7

"Highly permeable to water, but impermeable to NaCl" describes which of the following tubular segments?
-proximal tubule
-descending limb of loop of henle
-ascending limb of loop of henle
-distal tubule

Descending limb of loop of henle

8

The site of action of aldosterone is on which of the following tubular segments?
-proximal tubule
-descending limb of loop of henle
-ascending limb of loop of henle
-collecting duct

Collecting duct

9

Name the 3 major factors of autoregulation

Myogenic reflex of afferent arteriole
Tubuloglomerular feedback
Angiotensin II mediated vasoconstriction of efferent arteriole

10

Increased NaCl delivery to macula densa promotes ______

Vasoconstriction of afferent arteriole

11

A decrease in blood pressure would evoke a _______ of the afferent arteriole

Reflex vasodilation

12

During states of reduced renal blood flow, what substance is released from granular cells within wall of afferent arteriole?

Renin

13

How does angiotensin II normalize GFR in states of decreased RBF?

Causes vasoconstriction of efferent arteriole (increasing glomerular capillary hydrostatic pressure and hence, GFR)

14

When there is a water deficit in the body, osmolarity will be high, kidney should respond by secreting what kind of urine?

Concentrated

15

When osmole receptors in the hypothalamus sense a reduced serum osmolarity, ADH secretion will be increased or decreased?

Decreased

16

Glomerular filtrate in proximal tubule has what osmolarity

280-295mOsm/kg Same as plasma

17

2 requirements to secrete concentrated urine

High level of ADH
High osmolarity of medullary interstitial fluid

18

What are the 2 stimuli for ADH

Hyperosmolarity
Volume depletion