plasma membranes Flashcards
(40 cards)
what are the key components od the plasma membrane
Phospholipid bilayer- This is made up of phospholipids with hydrophilic heads and hydrophobic tails.
Cholesterol- This adds stability.
Proteins- These may be intrinsic and extrinsic proteins.
Glycoproteins- These are proteins attached to a carbohydrate.
Glycolipids- These are lipids attached to a carbohydrate.
what does the phospholipid bilayer contain
Each phospholipid molecule is made up of a hydrophilic ‘head’ and a two hydrophobic ‘tails’.
what does the phospholipid bilayer arrangement make them do
This causes phospholipids to arrange themselves into a bilayer so that the hydrophilic heads are facing out (towards water) and the hydrophobic tails are facing in (away from water).
This arrangement creates a hydrophobic centre in the bilayer so that water-soluble substances cannot pass through.
what does cholesterol do
provide stabilty and maintain the permeability
how does the cholestorol reduce the fluidity in the membrane
Cholesterol molecules consist of a hydrophilic and hydrophobic region. The hydrophobic regions bind to phospholipid fatty acid tails, causing them to pack more closely together.
This reduces the fluidity of the cell membrane
what are the types of proteins
intrinsic and extrinsic
what are insintric proteins and what does it do
Intrinsic (or integral) proteins are embedded through both sides of the phospholipid bilayer.
These proteins include channel and carrier proteins which transport large molecules and ions across the membrane.
what are extrinsic proteins and what do they do
Extrinsic (or peripheral) proteins are present on only one side of the phospholipid bilayer.
These proteins provide support to the membrane or may be involved in cell signalling.
what are glycoproteins and glycolipids
Glycoproteins consist of intrinsic proteins attached to carbohydrates, whereas glycolipids consist of lipids attached to carbohydrates.
what are glycoproteins and glycolipids involved in
Cell adhesion- This is the attachment of cells to one another.
Cell recognition- This allows cells to recognise one another.
Cell signalling- This is communication between cells.
what are the two types of membrane
cell surface membrane
membrane around organelles
what are the roles of both types of membrane
Cell-surface membranes- These surround cells to act as a barrier between the cell and its environment, controlling which substances enter and leave the cell.
Membranes around organelles- These surround organelles (e.g. mitochondria) to act as a barrier between the organelle and the cytoplasm, dividing the cell into different compartments (this is sometimes called compartmentalisation).
what are the factors that affect the permeability of membrane
temperature
solvent
length of the tails
cholesterol
,
what does temperature affect the permeability
At low temperatures (below 0°C)- Phospholipids do not have much kinetic energy. They are packed closely together to form a rigid cell membrane, decreasing the permeability of the membrane.
At medium temperatures (0 - 40°C)- As temperature increases, phospholipids have more kinetic energy so they move faster and aren’t packed as closely together. This increases the permeability of the membrane.
At high temperatures (above 40°C)- The phospholipid bilayer breaks down. Channel and carrier proteins denature, meaning they cannot control what enters or leaves the cell. These effects increase the permeability of the membrane.
how does solvent affect the permeabilty
Solvents are liquids that have the ability to dissolve substances.
When cells are placed in a solvent such as ethanol, thephospholipids dissolve, causing the membrane to become morefluid. Thisdisrupts the structureof the cell membrane to make itmore permeable.
Increasing theconcentrationof the solvent will furtherincrease the permeabilityof the cell membrane.
what is diffusion
Diffusion is the net movement of particles from an area of higher concentration to an area of lower concentration.
is diffusion a passive process
yes
what are the types of diffusion
Simple diffusion
Facilitated diffusion
what is simple diffusion
Some molecules can diffuse directly across cell membranes in a process known as simple diffusion.
why can oxygen and carbon dioxide diffuse by simple diffusion
Small- This means that they can pass through the spaces between phospholipids.
Non-polar-This means that they can dissolve in the hydrophobic core of the cell membrane.
what is facilitated diffusion
Large or polar molecules can cross cell membranes in a process known as facilitated diffusion.
what are the two types of proteins that facilitated diffusion involves
Carrier proteins
Channel proteins
how do carrier proteins work
A large molecule attaches to a carrier protein.
This causes the carrier protein to change shape.
The carrier protein releases the molecule on the opposite side of the membrane.