Platelet Function Test Flashcards

1
Q

Obsolete test; reflects the platelets function

A

Bleeding time

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2
Q

Provides an estimate of the integrity of the platelet plug

A

Bleeding time

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3
Q

Measures the interaction between the capillaries and platelets

A

Bleeding time

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4
Q

An infrequently performed _______ of platelet adhesion and aggregation on locally injured vascular sub endothelium

A

In vivo measurements

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5
Q

Method uses a lancet to make small, controlled puncture wound

A

Dukes Method

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6
Q

Reference interval of Dukes Method

A

2- 9 minutes

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7
Q

A blood pressure cuff is inflated at 40 mmhg

A

Standardized/ modified Ivy method

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8
Q

A calibrated spring loaded lancet is trigger on the __________ few inches distal to the ____________

A

Volar surface of forearm
Antecubital crease

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9
Q

How many incision made in standardized method

A

2

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10
Q

Reference interval for modified ivy method

A

2-9 mins

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11
Q

Degree of clot retraction is DIRECTLY PROPORTIONAL to

A

Number of platelets

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12
Q

Degree of clot retraction is INVERSELY PROPORTIONAL to

A

Hematocrit and fibrinogen

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13
Q

Evaluates how well platelets keep the clot adhered to the side of specimen tube

A

Clot retraction

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14
Q

Top tube used in clot retraction

A

Red tube (whole blood)

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15
Q

Examine clot in clot retraction in

A

1, 2, 4 and 24

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16
Q

Happens after 30 mins in clot retraction

17
Q

Remains serum after clot forms

18
Q

screening test for dengue

A

capillary fragility test

19
Q

capillary fragility test is known as

A

Rumpel-Leede Capillary Fragility Test or Tourniquet Test

20
Q

A blood pressure cuff is applied and inflated to a point between the systolic and diastolic blood pressures for 5 minutes

A

capillary fragility test

21
Q

Results in Capillary Fragility Test

A

10 or more petechiae per square inch

22
Q

dengue hemorrhagic fever

A

20 or more petechiae per square inch

23
Q

Capillary Fragility test has high specificity

24
Q

confirmatory test for dengue fever

25
size of petechiae
<3mm - 4mm
26
size of purpura
3mm-1cm
27
size of ecchymoses
>1cm
28
Adherence of platelets to glass surfaces
platelet adhesion
29
reference value in platelet adhesion
>25% retained normal <25% retained abnormal
30
platelet adhesion is a reliable method?
no
31
method for platelet adhesiveness to glass beads (diagnosis of Von Willebrand Disease)
Salzmann method
32
Platelet rich plasma is treated with known aggregating agents
Platelet aggregation
33
use to measure platelet aggregation
spectrophotometer
34
aggregating agents
Thrombin Restocetin Epinephrine Snake Venom Collagen ADP
35
Platelet aggregation is based on variation of
Born Method