Poisonous challenges Flashcards

(20 cards)

1
Q

poison

A

any substance that disturbs homeostasis

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2
Q

routes of exposure to poison

A
  • ingestion
  • skin
  • inhalation
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3
Q

poisons excreted by:

A
  • being sick
  • diarrhoea
  • coughing
  • swelling
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4
Q

classification for poison from animal

A

zootoxin

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5
Q

classification for poison from plant

A

phytotoxin

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6
Q

classification for poison from microbial

A

endo- or ecto- toxin

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7
Q

classification for poison from fungi

A

mycotoxin

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8
Q

classification for poison from inorganic sources

A

minerals or metals

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9
Q

susceptibility to poisons

A

route of exposure determines rate of absorption
- there are differences between species and breeds

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10
Q

factors affecting susceptibility

A
  • adaptation/accumulation
  • liver or kidney damage
  • trace element deficiencies
  • physiological state, e.g. pregnancy, age
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11
Q

poisonous plants

A
  • long history
  • most toxic species were identified by 1700s
  • many beneficial plants are toxic in excess
  • 10/20% animal food poisoning due to plants
  • animals try to avoid eating dangerous plants
  • range of compounds can make a plant poisonous
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12
Q

alkaloids

A
  • alkaline like
  • largest group, 4000 diff. compounds
  • in 10% of all plants
  • modified in liver prior to excretion
  • produces similar activity to numerous nerve transmitters
  • can have therapeutic uses
  • generally taste bitter
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13
Q

glycosides

A
  • not toxic
  • can have positive effects on health
  • 4 classifications
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14
Q

4 classifications of glycosides

A
  • cyanogenic
  • goitrogenic
  • cardiac
  • saponins
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15
Q

nitrates & nitrites

A
  • plants take up N as nitrates = formation of proteins
  • converted to toxic nitrites when eaten
  • reacts w/ haemoglobin to form methaemoglobin
  • animals can adapt to fight it
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16
Q

oxalates

A
  • found in most plants
  • seasonal variation
  • influenced by soil type
  • leaves usually . roots
  • form insoluble Ca salts
  • speedy consumption of plants makes more susceptible
17
Q

pesticides

A
  • made of many chemicals
  • developed to control pests
  • can affect non-target animals
  • whereabouts needs to be constantly monitored
18
Q

possible ways pesticides affect metabolism

A
  • neurotoxins
  • anticoagulant
  • gastrointestinal distress & dehydration
  • hepatic stress & liver failure
  • disruption of cellular ionic gradient
19
Q

minerals as toxins

A
  • most minerals are toxic in excess
  • most lead to chronic toxicity
  • need to take other minerals to reduce risk
20
Q

mycotoxins

A
  • over 500 identified
  • produced by moulds