Population genetics and natural selection Flashcards
(14 cards)
2 reasons why we might need to estimate frequencies of genotypes in a population
- to predict how many individuals will inherit a genetic disease
- to estimate the proportion of individuals who are carriers of a genetic disease
how do we predict genotypes in a population
by using the Hardy-Weinberg equation where:
p = dominant allele frequency
q = recessive allele frequency
p^2+2pq+q^2=1
what are the 7 ways an allele frequency can change
- non random mating
- assortative mating
- inbreeding - random genetic drift
- bottle neck effect
- founder effect
- Natural selection
- Gene flow or migration
- Mutation
what is random genetic drift
a random change in allele frequencies due to sampling error over generations
what is the bottle neck effect
a drastic reduction in a population’s size due to a sudden event, like a natural disaster or human activity
results in drastic change in allele frequency as one allele can be completely lost
what is the founder effect
The founder effect, in genetics, refers to the loss of genetic diversity that occurs when a new population is established by a small group of individuals from a larger population. This small founding population may not be a representative sample of the genetic variation of the original population, leading to differences in allele frequencies and a reduced range of traits in the new population.
what are the 3 types of selection
- disruptive selection
- directional selection
- stabilizing selection
what is disruptive selection
a type of natural selection where individuals with extreme traits have a higher fitness than those with intermediate traits
- the 2 extremities are picked for and the intermediate is picked against
what is directional selection
Directional selection is a type of natural selection where a population evolves toward one extreme of a trait spectrum
- only one of the extreme traits are picked for
what is stabilizing selection
a type of natural selection where individuals with intermediate traits or phenotypes have a higher fitness than individuals with extreme traits
- the intermediate trait is picked for and the extremities are picked against
what is sexual selection
natural selection arising through preference by one sex for certain characteristics in individuals of the other sex
certain trait is found more attractive than another and is selected for
what is frequency dependent selection
the concept that the fitness of a trait or phenotype is influenced by its frequency within a population
- fitness of a genotype is influenced by how rare or common it is
what is the spatial disruptive of genetic variation
The spatial distribution of genetic variants is jointly determined by geography, past demographic processes, natural selection, and its interplay with environmental variation
what is cline
the gradual geographic change in genetic/phenotype composition