PP Bioestadistics Flashcards

(48 cards)

0
Q

What is the Median?

A

Middle value

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1
Q

What is the mean?

A

Average

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2
Q

What is the Mode?

A

Most frequent value

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3
Q

What does sensitivity tell you?

A

People that have the disease with a (+) test
= A / (A+C)
= 1 - false negative rate

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4
Q

What does specificity tell you?

A

People that don’t have the disease with a (-) test
= D / ( D+B)
= 1 - false positive rate

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5
Q

What does PPV tell you?

A

Probability of having the disease with a (+) test

= A / ( A + B)

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6
Q

What does NPV tell you?

A

Probability of not having the disease with a (-) test

= D / (C+ D)

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7
Q

What does incidence tell you?

A

Number of new cases in a period of time

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8
Q

What does prevalence tell you?

A

Total of cases

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9
Q

What does OR tell you?

A

Diseased are x time more likely to see risk factor

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10
Q

What does Confidence interval = 96% tell you?

A

95% sure it lies within the interval

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11
Q

What does RR tell you?

A

Risk of getting the disease with known exposure

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12
Q

What is NNT?

A

NNT to change 1 life

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13
Q

What does a p value < 0.5 tell you?

A

Random chance that you will be wrong 1 time out of 20

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14
Q

What does a Null hypothesis tell you?

A

Nothing’s happening

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15
Q

What does Pawer tell you?

A

Probability of detecting a < > when there is one

P= (1- beta)

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16
Q

What is Type I error?

A

False positives
Admitting there is a < > when there is not
Alfa = probability of making a TI error

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17
Q

What is Type II error?

A

False negative
Denying there is a < > when there is one
Beta = probability of making a TII error

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18
Q

What is Accuracy?

A

Validity “truth”

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19
Q

What is Precision?

A

Reliability “keep making the same mistake”

20
Q

What are the phases of clinical trials?

A

P I: Is the drug safe? “ toxicity”
P II: Does the drug work? “ efficacy”
P III: Does the drug work better? “ comparison”
P IV: post- marketing

21
Q

What is a Cohort study?

A

Prospective or Retrospective study that provides incidence

Uses RR

22
Q

What is a Case control study?

A

Retrospective study that

Uses OR

23
Q

What is a Cross Sectional study?

A

Provides prevalence

24
What is a Case Report?
Describes an unusual pt
25
What are Consensus Panels?
Panel of experts provides a recommendation
26
What is clinical wisdom?
I think .... Paper
27
What is a Meta-analysis?
Tries to combine data from many trials
28
What is Selection bias?
Nonrandom assigment | Berksons bias
29
Absolute risk reduction?
AAR = [c / ( c+d) ] - [a / (a +b) ]
30
What is Recall bias?
Knowledge of presence of disorder alters recall by subjects
31
What is Sampling bias?
Subjects are NOT representative of the general population
32
What is Late-look bias?
Information gather at an inappropriate time
33
What is a Procedure bias?
Not equal attention to both groups
34
What is a Confounding bias?
When the FACTOR is related with the exposure an the outcome
35
What is a Lead-time bias?
Confusing Early detection with increase of survival
36
What is the Observer-expectancy effect?
Believe of research affects the outcome
37
What is the Hawthrone effect?
People being study change in behavior because they know they been study
38
Ways to reduce Bias?
``` Blind studies Placebo control group Crossover studies Randomization Matching ```
39
What are the percentage of the 1,2,3 standard deviation?
1- 68% 2- 95% 3- 99.7%
40
Standard Deviation and Standar error of the mean ( SEM)?
``` SD = õ SEM = SD / raiz cuadrada de n ```
41
Positive and negative Skew?
(+) -> mean > median > mode | (-) -> mean < median < mode
42
Values of confidence interval (CI)?
``` 90% = 1.645 95% = 1.96 99% = 2.57 ```
43
t - test?
Difference between the Mean of 2 groups
44
ANOVA?
Difference between the Mean of 3 or more groups
45
Chi-square?
Compare difference between % or proportion
46
Whatch are the sleep stages?
Awake (eyes open) -> alert, beta wave { high frequency, lowest amplitude} Awake (eyes closed) -> alpha wave Stage N1 -> light sleep, theta wave Stage N2 -> deeper sleep, K complexes Stage N3 -> deepest, non-REM, bedwetting, delta waves {lowest frequency, highest amplitude} REM -> Dreaming, beta waves
47
Developing stages?
0-12mo Infant -> Parents, Start, Observing 12-36mo Toddler -> Child, Rearing, Working 3-5 years Preschool -> Don't, Forget; they're still, Learning