PRIME Videos Flashcards

1
Q
Which of the following innate immune cells are phagocytic? 
macrophages 
basophils 
dendritic cells 
neutrophils
A

macrophages
neutrophils
dendritic cells

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2
Q

which innate immune cell is implicated in immediate-type hypersensitivity (allergies) ?

A

basophils

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3
Q

which of the following best pairs an innate immune receptor type with its function?

A. toll-like receptor (TLR); recognition of foreign extracellular proteins to initiate an inflammatory cascade

b. TLR; recognition of specific antigens through self /nonself discrimination
c. TLR; recognition of pathogen associated molecular patterns to elicit an immune response

A

C

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4
Q

which of the following innate immune cells would best obliterate a viral infection?

A

Natural killer cells

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5
Q

what is the key antigen presenting cell?

A

dendritic cell, macrophages, and B-cells are all antigen presenters however dendritic cells are usually considered the most important cells incvolved in antigen presentation to T-cells

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6
Q

t/f the adaptive immune system provides a delayed and pathogen specific response to infection

A

true

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7
Q

major histocompatibility complex (MHC) genes code for proteins that play an essential role in which of the following?
antigen presentation to B cells/T-cells/or both

A

T-cell

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8
Q

which of the following is correctly characterized as the most prevalent antibody in serum as well as an opsonin that can cross the placenta

A

IgG

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9
Q

t/f CD4+ T cells recognize MHC I, while CD8+ T cells recognize MHC II

A

false
CD4+ T cells recognize MHC II
CD8+ T cells recognize MHC 1

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10
Q

what is the effector cell for humoral immunity ?

A

plasma cell

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11
Q

what are the three key functions of complement?

A

opsonization, inflammation and lysis

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12
Q
which of the following enzymes is formed by all three pathways of complement activation?
C1 convertase 
C2 '
C3 '
C4 '
A

C3 convertase

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13
Q

t/f the lectin pathway requires antibodies for activation

A

false

the lectin pathway is activated via binding of bacterial mannose to complement mannose binding protein

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14
Q

which of the following is a function of C3b?

A

opsonization

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15
Q

which of the three complement pathways is directly associated with the adaptive immune system?
alternative
lectin
classical

A

classical

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