Psych: Stimulants

Question 1

How do stimulants work for ADHD?

Answer 1

Block reuptake of monoamines via VMAT and increase NT release (NE, DA, and 5HT)

Question 2

What are some common side effects of stimulants? (6)

Answer 2

GI Upset
Headache
Decrease Appetite (weight loss and reduced growth)
Insomnia
Anxiety
Elevated BP

Question 3

What is the most serious rare effect of stimulants?

Answer 3

Sudden cardiac death

Question 4

What is a unique side effect of stimulants that involves the skin?

Answer 4

Chemical Leukoderma

-with Daytrana patch

Question 5

What stimulants are used to treat ADHD that are amphetamine derivatives? (5)

Answer 5

Amphetamine
Dextroamphetamine

Lisdexamfetamine

Methylphenidate
Dexmethylphenidate

Question 6

What are some non-stimulants used for ADHD? (3)

Answer 6

Atomoxetine

Guanfacine and Clonidine (α2 agonists)

Question 7

How fast is the onset of most stimulants?

Answer 7

24 hours

Question 8

Are stimulants available to pick up without doctor’s orders?

Answer 8

No, controlled substance (1 month supply)

-most states allow 3 months (not MO though)

Question 9

What form of medication does dextroamphetamine/AMP/Adderal come in and how long does it last??

Answer 9

Tablet

-immediate release (4-6 hr)

Question 10

What form of medication does dextroamphetamine sulfate/Procentral come in and how long does it last??

Answer 10

Liquid

-immediate release (4-6 hr)

Question 11

What form of medication does amphetamine sulfate/Evekeo come in and how long does it last??

Answer 11

Capsule

-immediate release (4-6 hr)

Question 12

What form of medication does dextroamphetamine/Zenzidi come in and how long does it last??

Answer 12

Tablet

-immediate release (4-6 hr)

Question 13

What form of medication does dextroamphetamine/Adderall XR come in and how long does it last??

Answer 13

Capsule

-extended release (8-12 hrs)

Question 14

What form of medication does dextroamphetamine/Dexedrine come in and how long does it last?

Answer 14

Capsule

-extended release (8-10hrs)

Question 15

What form of medication does amphetamine/Dyanavel XR come in and how long does it last?

Answer 15

Liquid**
-Extended release (13 hrs)

great for people who cannot swallow well

Question 16

What form of medication does lisdexamfetamine/Vyvanse come in and how long does it last?

Answer 16

Capsule

-extended release (10-12hrs)

Question 17

What form of medication does Amphetamine/Mydayis come in and how long does it last?

Answer 17

Capsule

-extended release (16hrs**)

Question 18

What form of medication does dexmethylphenidate/Focalin come in and how long does it last?

Answer 18

Tablet

-immediate release (4-6 hr)

Question 19

What form of medication does methylphenidate/methylin oral solution come in and how long does it last?

Answer 19

Liquid

-immediate release (3-4hrs)

Question 20

What form of medication does methylphenidate/ritalin come in and how long does it last?

Answer 20

Tablet

-immediate release (3-4hrs)

Question 21

What form of Adzenys come in and how long does it last?

Answer 21

Extended release, oral dissolving tablet

-no water necessary

Question 22

What form of medication does methylphenidate/ritalin-SR come in and how long does it last?

Answer 22

Tablet

-Sustained release (4-8hrs)

Question 23

What form of medication does methamphetamine/Desoxyn come in and how long does it last?

Answer 23

Tablet

-Sustained release (4-8hrs)

Question 24

What form of medication does methylphenidate/aptensio XR come in and how long does it last?

Answer 24

Capsule

-Extended release (12 hrs)

Question 25

What form of medication does methylphenidate HCl/Concerta come in and how long does it last?

Answer 25

Tablet | -Extended release (10-12hrs)

Question 26

What form of medication does methylphenidate ER/comtempla XR-ODT come in and how long does it last?

Answer 26

Tablet | -Extended release (12 hrs)

Question 27

What form of medication does methylphenidate transdermal/Daytrana come in and how long does it last?

Answer 27

Transdermal patch** | -Extended release (10-12hrs)

Question 28

What form of medication does dexmethylphenidate HCl/Focalin XR come in and how long does it last?

Answer 28

Capsule | -Extended release (6-10hrs)

Question 29

What form of medication does methylphenidate HCl/metadate CD come in and how long does it last?

Answer 29

Capsule | -Extended release (8-10hrs)

Question 30

What form of medication does methylphenidate HCl ER/ritalin LA come in and how long does it last?

Answer 30

Capulse | -Extended release (8-10hrs)

Question 31

What form of medication does methylphenidate HCl/QuilliChew come in and how long does it last?

Answer 31

Chewable tablet** | -Extended release (8hrs)

Question 32

What form of medication does methylphenidate/Quillivant XR come in and how long does it last?

Answer 32

Liquid ** | -Extended release (8, 10, 12hrs)

Question 33

MOA of atomoxetine?

Answer 33

Blocks NET reuptake of NorE

Question 34

MOA of guanfacine/clonidine?

Answer 34

Agonist of CNS α2

Question 35

Onset of activity for non-stimulants?

Answer 35

1-4+weeks | -in contrast to stimulants (24hrs)

Question 36

Why are non-stimulants used?

Answer 36

Useful for patients that are intolerant to stimulant effects

Question 37

What form of medication does atomoxetine come in and how long does it last?

Answer 37

Capsule | -24 hours

Question 38

What form of medication does clonidine come in and how long does it last?

Answer 38

Tablet | -12-24hrs

Question 39

What form of medication does Guanfacine come in and how long does it last?

Answer 39

Tablet | -12-24hrs

Question 40

Should you crush, chew, or break the tablets of guanfacine or clonidine?

Answer 40

nope

Question 41

What BP effect happens when you stop taking clonidine and guanfacine?

Answer 41

Rebound HTN