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Flashcards in Psychopharmacology Deck (66)
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1

_________________ produce effects similar to those produced by a neurotransmitter.  ____________________ exert their effects by mimicking the effect of a neurotransmitter at a receptor site, while ____________________ attach to a binding site on a receptor cell (a site other than the one used by the neurotransmitter) and facilitate the action of the neurotransmiter).

Agonists.

2

________________ produce an effect opposite the effect produced by a neurotransmitter or an agonist.

Inverse agonists.

3

___________________ produce effects that are similar to (but less than) the effects produced by a neurotransmitter or an agonist.

Partial agonists.

4

___________________ produce no activity in the cell on their own but, instead, reduce or block the effects of a neurotransmitter or agonist.  __________________ exert their effects by attaching to a neurotransmitter's receptor site, while _____________________ attach to a binding site on a receptor cell (a site other than the one used by the neurotransmitter) and interfere with the action of the neurotransmitter.

Antagonists.

5

Because of the increased risk for adverse drug effects, a general rule when prescribing drugs for ______________ is to "start low and go slow."

Older adults.

6

In comparison to Caucasians, higher proportions of ____________ and, to somewhat lesser degree, __________________ are slower or poorer metabolizers of specific isoenzymes, which explains why they are more sensitive to the therapeutic and side effects of certain drugs such as neuroleptics, benzodiazepines, lithium, and some antidepressants.

  • Asians
  • African-Americans

7

Chlorpromazine

  • Thorazine
  • Conventional AntiPsychotic
  • Parent drug: Phenothiazine

8

Fluphenazine

  • Prolixin
  • Conventional Antipsychotic
  • Parent drug: Phenothiazine

9

Thiothixene

  • Narvane
  • Conventional Antipsychotic
  • Parent drug: Thioxanthene

10

Haloperidol

  • Haldol
  • Conventional Antipsychotic
  • Parent drug: Butyrophenone

11

Clozapine

  • Clozaril
  • Atypical Antipsychotic
  • Parent drug: Dibenzodiazepine

12

Resperidone

  • Risperdal
  • Atypical Antipsychotic
  • Parent drug: Benzisoxazole

13

Olanzapine

  • Zyprexa
  • Atypical Antipsychotic
  • Parent drug: Thienobenzodiazepine

14

Quetiapine

  • Seroquel
  • Atypical Antipsychotic
  • Dibenzothiazepine

15

Amitriptyline

  • Elavil, Endep
  • Tricyclic Antidepressant (TCA)

16

Doxepin

  • Sinequan, Adaptin
  • Tricyclic Antidepressant (TCA)

17

Imipramine

  • Trofranil
  • Tricyclic Antidepressant (TCA)

18

Clomipramine

  • Anafranil
  • Tricyclic Antidepressant (TCA)

19

Nortriptyline

  • Pamelor
  • Tricyclic Antidepressant (TCA)

20

Fluoxetine

  • Prozac
  • SSRI

21

Fluvoxamine

  • Faverin, Luvox
  • SSRI

22

Paroxetine

  • Paxil
  • SSRI

23

Sertraline

  • Zoloft
  • SSRI

24

Isocarboxazid

  • Marplan
  • MAOI

25

Phenelzine

  • Nardil
  • MAOI

26

Tranylcypromine

  • Parnate
  • MAOI

27

Diazepam

  • Valium
  • Benzodiazepine

28

Alprazolam

  • Xanax
  • Benzodiazepine

29

Oxazepam

  • Serax
  • Benzodiazepine

30

Triazolam

  • Halcion
  • Benzodiazepine