pyoderma gangrenosum

Question 1

what is pyoderma gangrenosum

Answer 1

rare, non-infectious inflammatory disorder

Question 2

causes of pyoderma gangrenosum

Answer 2

idiopathic
IBD
rheumatological: RA, SLE
haematological: myeloproliferative, lymphoma, myeloid leukaemias, monoclonal gammopathy
granulomatosis with polyangiitis
PBC

Question 3

features of pyoderma gangrenosum

Answer 3

typically affect lower limb, of site of minor injury
starts quite suddenly, small pustule, red bump
ulcer described as purple, violaceous and undermined

Question 4

management of pyoderma gangrenosum

Answer 4

oral steroids first line
other immunosuppressive therapy: ciclosporin, infliximab