Quiz #2: Depression Flashcards

(48 cards)

1
Q

Grief

A

-Subjective state that follows loss. -Grief is universal; however, the way in which it is expressed is culturally determined.

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2
Q

Depression

A

-Clinical disorder that is severe, maladaptive, and incapacitating.
-Extreme sadness, hopelessness, worthlessness and lack of motivation.

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3
Q

Mania

A

Elevated, expansive, or irritable mood, extreme sense of wellbeing with grandiosity.

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4
Q

How does culture affect depression?

A

Affects symptomatic expression, clinical presentation and effective treatment. (Most people now believe in a biological basis for this disorder)

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5
Q

Statistics for Depression

A

-Lifetime risk for MDD is 7 – 12% for men and 20 – 30% for women
-More than 50% of those who have one episode will eventually have another, and 25% of patients will have chronic, recurrent MDD
-1/3 of all people with MDD seek help, are accurately diagnosed, and obtain appropriate treatment
-High incidence of MDD is found among patients hospitalized for medical illness
MDD high prevalent in primary care settings

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6
Q

Who is important to screen for MDD?

A

Women of reproductive age. Especially those who have children or plan to become pregnant

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7
Q

Etiology of Depression

A
  1. Biological Theories
  2. Cognitive Theory
  3. Learned Helplessness
  4. Diathesis Stress Model
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8
Q

Etiology of Depression: Biological Theories

A
  • No single biochemical model explains the causes of depression
  • Dominant theory is the dysregulation hypothesis
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9
Q

Dysregulation Hypothesis

A
  • Dysregulation in the amount or availability of 5-HT, the sensitivity of its receptors in relevant regions of the brain, and its balance with other neurotransmitters
  • 5-HT has important brain functions such as aggression, mood, psychomotor activity, irritability, appetite, sexual activity, etc.
  • 5-HT has an important role in the secretion of growth hormone, prolactin, and cortisol, all of which are found to be abnormal in people with depression
  • Most effective antidepressant agents, such as ECT and medications, have been found to enhance neurotransmission of 5-HT
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10
Q

Depression Etiology: Diathesis-Stress Model

A
  • Psychological / biological theory, and is basically the culmination of stress from life experiences (stress) and the vulnerability (diathesis) of a person, such as genetics, psychological, biological, or situational factors, that can lead to depression.
  • Example: A child who has a family history of depression (vulnerability / diathesis) and who has been exposed to a particular stressor, such as exclusion or rejection by his peers (stress) would be more likely to develop depression than a child with a family history of depression that has an otherwise positive social network of peers.
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11
Q

Depression Etiology: Cognitive Theory

A

Depression is seen as a cognitive problem arising from a person’s negative view of self, the world, and the future.

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12
Q

Depression Etiology: Learned Helplessness

A
  • Theory proposes that it is not trauma that produces depression but the belief that one has no control over important outcomes in life.
  • It is a behavioral state and a personality trait of one who believes that control over reinforces in the environment has been lost.
  • These negative expectations lead to hopelessness, passivity, and an inability to assert oneself.
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13
Q

Primary Risk Factors for Depression Include

A
  • Female
  • Unmarried
  • Low socioeconomic class
  • Early childhood trauma
  • Presence of negative life event, especially loss and humiliation
  • Family history
  • Ineffective coping ability
  • Postpartum time period
  • Medical illness
  • Absence of social support
  • Alcohol or substance abuse
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14
Q

Depression DSM-5 Criteria

A

Add later

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15
Q

What is an affect?

A

Outward expression of emotion

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16
Q

Depression Affects include

A
  • Sad
  • Flat
  • Blunted
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17
Q

Depression: Moods Include

A
  • Anxious
  • Sad
  • Worthless
  • Helpless
  • Angry
  • Hopeless
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18
Q

Depression: Physical Behavior and Appearance Include

A
  • Psychomotor retardation
  • Disheveled
  • Insomnia
  • Older than stated age
  • Loss of libido
  • Fixed gaze
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19
Q

Depression: Thought Processes Include

A
  • Poor Judgement
  • Indecisive
  • Intrusive, negative thoughts
  • Poor memory
  • Poor Concentration
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20
Q

What is SIG-E-CAPS?

A

Rapid screening for depression

21
Q

What does SIG-E-CAPS stand for?

A
  • Sleep changes: increase during day or decreased sleep at night
  • Interest (loss): of interest in activities that used to interest them
  • Guilt (worthless): depressed elderly tend to devalue themselves

-Energy (lack): common presenting symptom (fatigue)

  • Cognition/Concentration: reduced cognition &/or difficulty concentrating
  • Appetite (wt. loss); usually declined, occasionally increased
  • Psychomotor: agitation (anxiety) or retardations (lethargic)
  • Suicide/death preoccupation
22
Q

PHQ-9

A

-The most commonly used screening questionnaire for depression.

23
Q

Expected outcomes for patients with depression

A

Patient will be emotionally responsive and return to pre-illness level of functioning

24
Q

What actions by the nurse can be done to help the patient reach their expected outcomes?

A
  • Allow patient to recognize feelings
  • Analyze stressors and strengthen patient’s self-esteem
  • Increase patient’s sense of control, awareness of choices, and responsibility for behavior
  • Encourage healthy interpersonal ties with others
  • Promote understanding of maladaptive emotions and to acquire adaptive coping responses to stressors
25
Planning of care for patients with depression
- Safety is the highest priority! - Risk Assessment: Self harm or harm to others - Environment of Care: Suicide Prevention and Therapeutic Milieu - Patient Care: Safety, Therapy and Medications, Emotional Response And Social Functioning.
26
Depression Implementation: Nurse-Patient Relationship
- Patient may resist involvement through withdrawal and nonresponsiveness - Nurse needs to be quiet, warm and accepting - Develop rapport through shared time, even if patient talks little, and through supportive companionship
27
Physiological Treatments for Depression Include
- May need to monitor diet - Sleep Disturbances - Self-Care needs, such as bathing and dressing - Psychopharmacology
28
Depression Implementation: Expressing Feelings
Should reinforce that depression is self-limiting and that the future will get better
29
Depression Implementation: Cognitive Strategies Include
- Help patient explore feelings and their view of the problem. - Focus on modifying the patient’s thinking (they tend to focus on negative thinking) - Help patient examine accuracy of perceptions, logic and conclusions (move them from unrealistic to realistic goals; increase self-esteem; involve patient in productive tasks or activities
30
Therapeutic Communication Techniques Include
- Listening - Broad openings - Restating - Clarifying - Reflection - Silence
31
Depression: Psychopharmacology
- SSRIs* - TCAs* - MAOIs* - SNRIs - NDRI - NASSA
32
What is the primary cause of depression?
In depression, dysregulation of serotonin is the primary cause… either not enough serotonin or the body breaks down the serotonin before it can be used
33
How does SSRI’s treat depression?
SSRIs block the reuptake of serotonin, allowing for more serotonin to stay in the synaptic space and to activate the serotonin receptors  which is known to initiate the neurons known to affect mood, motor system, etc
34
How do MAOI’s treat depression?
monoamine oxidase is an enzyme that breaks down neurotransmitters (including serotonin and norepinephrine) – an MAOI inhibits that enzyme -> more epinephrine and serotonin
35
How do TCA’s treat depression?
work similar to SSRIs, except that they block reuptake of both serotonin and norepinephrine
36
SSRI’s Include
``` Citalopram (Celexa) Escitalopram (Lexapro) Fluoxetine (Prozac) Fluvoxamine (Luvox) Paroxetine (Paxil) Sertraline (Zoloft) ```
37
SSRI’s
- First-Line Treatment for Depression - Low risk for lethal overdose - Taper slowly (can cause discontinuation syndrome ie dizziness, Irritability, N/V and Insomnia)
38
SSRI’s Side Effects Include
- Insomnia - Headache - N/V - Sexual Dysfunction - Hyponatremia
39
What is Serotonin Syndrome?
- Rare and life-threatening event associated with SSRIs - Related to over-activation of the central serotonin receptors caused by either too high a dose or interaction with other drugs
40
Risk for Serotonin Syndrome is increased when
SSRI is administered with a second serotonin-enhancing agent, such as MAOI
41
Symptoms of Serotonin Syndrome Include
- Abdominal pain, N/V - Sweating, fever - Tachycardia, elevated BP - Altered mental status - Muscle spasms and increased motor activity
42
Tricyclic Antidepressants Include
Amitriptyline (Elavil) Clomipramine (Anafranil) Desipramine (Norpramin) Nortriptyline (Aventyl)
43
TCA’s: Side Effects Include
- Dry mouth, constipation, urinary retention, cardiac toxicity, sedation - Need cardiac workup before initiation of therapy
44
TCA’s Cautions
- Lethal in overdose | - Use cautiously in elderly, cardiac patients, seizure disorders, and liver or kidney dysfunction
45
MAOI’s Include
Isocarboxazid (Marplan) Phenelzine (Nardil) Tranylcypromine (Parnate)
46
MAOI’s: Dietary Restrictions Include
- Tyramine: meat that is pickled, aged, smoked or fermented; chocolate; beer, wine; fermented foods: aged cheese. - Can cause hypertensive crisis
47
MAOI’s are contraindicated with
- SSRI’s | - Interacts with numerous medications
48
Antidepressants and the Risk for Suicide
There is an increased risk for suicide 2-6 weeks after starting a patient on antidepressants