Quiz 2 Muscles Flashcards

1
Q

Smooth muscle more often responds to which kind of signals?

A

local and hormonal

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2
Q

What kind of muscle is the diaphragm?

A

skeletal

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3
Q

What are 5 functions of muscle tissue

A
  1. Producing body movements
  2. Stabilizing body positions
  3. Regulating Organ Volume
  4. Flow of substances within the body
  5. Producing heat
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4
Q

What is extensibility

A

ability to stretch without damaging the tissue

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5
Q

What is the diameter of muscle fibers?

A

10-100 microns

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6
Q

What is the sarcolemma

A

plasma membrane of muscle cell + external lamina

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7
Q

What separates the muscles into fascicles

What seprates muscles fibers from one another

A

perimysium

endomysium

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8
Q

What kind of fibers make up endomysium/ maybe peri and epimysium as well?

A

reticular fibers/ type III collagen

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9
Q

light band is isotropic or anisotropic?

A

Isotropic

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10
Q

what does anisotropic mean?

A

block light

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11
Q

label, specifically M line

A
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12
Q

M line represents

A

attachment of adjacent myosin molecules

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13
Q

What are the 3 types of protein that comprise Myofibrils?

A

contractile, regulatory, and structural

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14
Q

Out of the three protein types that make up Myofibrils…what kind is Myosin Light Chain Kinase (MLCK)

A

regulatory

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15
Q

Which kind of muscles use MLCK and why?

A

smooth, no troponin complex in smooth

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16
Q

what is titin

what does it do

A

structural protein in myofibrils

starts at Z-line and binds to thick filament. acts as molecular spring

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17
Q

What is myomesin

what does it do

A

structural protein in myofibrils

.attaches myosin thick filaments at M line

18
Q

What is nebulin

what does it do

A

structural protein in myofibrils

Regulates actin length

19
Q

What is alpha actinin

what does it do

A

structural protein in myofibrils

anchors actin to Z disk

20
Q

What is dystrophin

A

structural protein in myofibrils

21
Q

What are the three classes of intermediate filaments in myofibrils and where are they

Where are they important

A

desmin,vinmentin, and syemin

They are inbetween the contractile proteins and

they are particularly importnat at the Z-disk

22
Q

Troponin T binds to:

Troponin C binds to:

Troponin I binds to:

A

tropomyosin

calcium

actin and inhibits myosin binding

23
Q

Each myosin filament has how many actin filaments surrounding it?

24
Q

Myosin heads are N or C terminus?

25
Describe strucure of Myosin II --How many proteins in myosin head region and what are they
2 coiled coils of 2 alpha helices 6 2 heavy chains 2 essential light chains 2 regulatory light chains
26
skeletal muscle has what type of mysoin?
II
27
myosin thick filaments are ____ \_\_\_\_\_on the two ends
oppositely polarized
28
How many molecules of myosin make up one thick filament
300-600
29
label I H M and A band
30
During muscle contraction ___ \_\_\_ moves towards __ \_\_\_\_
z disk, A band
31
What decreases in teh sarcomere during muscle contraction?
H and I band
32
The binding of the myosin to hte myosin-binding site on actin causes release of _____ from the head of the myosin molecule. This results in a conformational change that pulls the actin towards the ____ end of hte actin filament
ADP minus
33
waht causes power stroke of myosin
loss of ADP from myosin
34
t/f release of actin filament requires hydrolysis of ATP
false, just requires the molecule
35
when in the muscle contraction is ATP hydrolysis requried?
recocking the head
36
In skeletal muscle, how many many cisternae are there / T tubule
2
37
SR cisternae are located where in the skeletal muscle sarcomere? - cardiac
junction b/w the A and I band .-Z disk
38
transvere portion of intercalated disks have what kind of junctional complex
fascia adherens/ broad desmosomes
39
What are smooth muscle cells surrounded by?
reticular fibers
40
what causes binding of actin/myosin in smooth muscle cells
phosphorylation of myosin light chaisn
41
wht are the two types of smooth muscle units
visceral and multiunit
42
which type of smooth muscle type is sparsely innervated and has extensive gap junctions
visercal