QUIZ 6 Flashcards

(159 cards)

1
Q

components of circulatory system

A
  • blood
  • red bone marrow
  • heart
  • vessels
  • lymphatic system
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2
Q

blood as connective tissue

A
  • connective tissue:
  • cells- various blood cells (RBCS, WBC, macrophages)
  • fluid- water based fluid
  • fibers- dissolved protein fibers (fibrin)
  • ground substance- fluid ground substance -> plasma
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3
Q

blood

A
  • plasma- 55% (volume)
  • H2O- 92% (weight)
  • proteins- 7%
  • electrolytes- 1%
  • cells and cell fragments- 45% (volume) -> red 99%, white .01%, platelets .99% (formed elements)
  • hematocrit- measure of blood cell volume percentage, a common test for anemia
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4
Q

red blood cells

A
  • erythrocytes
  • hemoglobin- protein that transport oxygen and carbon dioxide
  • transports from high oxygenated regions to other parts
  • transports CO2 form high concentration back to lungs
  • formed in hemopoietic marrow (red marrow)
  • destroyed (phagocytized) in liver and spleen
  • spleen stores RBC’s
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5
Q

antigen and antibodies

A
  • antigen- substances capable of stimulating an immune response -> some are bound to cell surface (surface antigens)
  • antibody- proteins that recognize and immobilize a specific antigen -> stimulate an immune response
  • when antibodies bind to erythrocytes surface antigens, this leads to agglutination (clumps of cells that can prevent normal blood circulation and/or cell rupture)
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6
Q

blood types

A
  • receiving blood that isnt your blood type leads to agglutination
  • ABO blood type-
  • type A- specific surface antigen A -> produce anti-B antibodies -> type B binds and causes agglutination
  • type B- surface antigen B -> anti-A antibodies
  • type AB- surface antigens A and B -> they have no anti-A or anti-B -> universal acceptor
  • type O -> neither surface antigen A or B -> produces both anti-A and anti-B antibodies -> universal donor
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7
Q

would we expect agglutination to occur in a type A person who receives a transfusion of type AB blood

A
  • yes

- type A has anti-B antibodies and AB blood has surface antigen B

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8
Q

Rh

A
  • Rh positive- have surface antigen D and no anti-D antibodies
  • Rh negative- have no surface antigen D and no anti-D antibodies (except when this person has be exposed to Rh+ blood previously)
  • if a pregnant persons child is Rh+ and the mother is Rh- -> the blood from the child transfers to the mother
  • if she has another baby her Rh+ can transfer to the baby and cause agglutination -> problem!
  • checked in pregnant mothers
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9
Q

white blood cells

A
  • leukocytes
  • immune response agents
  • defend against pathogens
  • 5 major types
  • leukemia:
  • increased production of leukocytes at expense of erythrocytes and platelets within red bone marrow
  • bone marrow transplant may be prescribed in some cases
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10
Q

platelets

A
  • thrombocytes
  • small irregular cell fragments
  • form clots in combination with dissolved fibrin
  • release clotting agent
  • thrombus- stationary clot in vessel -> can be bad is in pulmonary system
  • embolus- detached clot
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11
Q

heart: pericardium

A
  • outer layer limits movement of heart within thorax
  • outer layer is attached to other organs (diaphragm)
  • outer layer prevents the heart from being over filled with blood
  • outer layer -> fibrous pericardium -> dense connective tissue
  • deeper layer- provides lubrication
  • serous pericardium (inner layer)- 2 layers -> parietal serous membrane (loose connective tissue and epithelium) and visceral serous
  • mediastinum
  • attached to other organs -> diaphragm
  • prevents the heart from being overfilled with blood
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12
Q

pulmonary circulation

A
  • receives deoxygenated blood from the right side of heart -> to lungs
  • CO2 is passed in tissue
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13
Q

systemic cirulation

A
  • oxygenated

- left side of heart -> blood supply to the rest of the organs (systemic cells)

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14
Q

pericarditis

A
  • swelling and irritation of serous membrane and heart
  • sharp pain in heart
  • inner layers of pericardium provide lubrication to prevent this
  • pain is picked up by left arm and heart
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15
Q

fibrous pericardium

A
  • dense connective tissue
  • outer layer of pericardium
  • prevents distention
  • prevents overfilling
  • continuous with the diaphragm and major vessels (inferior vena cava, aorta, esophagus)
  • binds strongly to the inferior vena cava and aorta and esophagus
  • outermost layer of pericardium
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16
Q

serous pericardium

A
  • inner layer of pericardium
  • 2 layers -> parietal serous membrane and visceral serous pericardium (epicardium)
  • a serous membrane is a combination of loose connective tissue and epithelium
  • lines the inner part of the fibrous pericardium (parietal layer) and the outside of the heart (visceral layer)
  • epithelium layer of tissue is pointing inward, facing the space in between the parietal and visceral layers -> produces the serous fluid -> prevents friction between the visceral and parietal layers of serous pericardium
  • lubrication
  • parietal layer- outer layer -> touching the fibrous pericardium
  • visceral layer- surround the heart -> outer layer of the heart wall
  • visceral layer is also known as epicardium
  • areolar connective tissue and fat
  • binds the simple squamous epithelium-> producing the serous fluid
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17
Q

myocardium

A
  • deep to the visceral layer of the serous pericardium
  • cardiac muscles cells
  • deep to visceral layer
  • short, branched cardiac muscles cells
  • striated muscle
  • intercalated discs- electrical junctions
  • open gap junctions
  • ions pass from one cell to another freely -> depolarization of one cell causes continuous flow -> systemic and smooth contraction of heart muscle wall
  • fast and continuous signal
  • cells are shorter, branched, striated, y-shaped
  • thickest part
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18
Q

endocardium

A
  • deepest layer of heart
  • surrounding the atria and ventricles
  • areolar connective tissue and endothelium (simple squamous epithelium)
  • has areolar connective tissue which connects the endothelium to myocardium
  • endothelium layer of the endocardium is simple squamous epithelium
  • continuous with endothelium that lines the blood vessels of the arteries and veins
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19
Q

fibrous skeleton

A
  • connected to myocardium
  • dense connective tissue that reinforces the valves found in between heart chambers
  • serves as electrical insulator between atria and ventricles
  • septum
  • provides support to valves
  • forms a layer in between atrium and ventricles -> prevents the electrical flow from atria to ventricles (electrical insulator)
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20
Q

semilunar vales

A

-between ventricles and arteries

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21
Q

chambers

A
  • atrium receives blood from outside of heart from veins (vena cava and pulmonary veins)
  • ventricles expel blood into arteries
  • ventricles- expel blood into arteries
  • right atrium receives deoxygenated blood from vena cava
  • flows into the right ventricle while relaxed
  • ventricle expels the deoxygenated blood into the pulmonary artery/ circulation
  • pulmonary veins returns oxygenated blood into left atrium
  • flows into the left ventricle to systemic cells via aorta
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22
Q

valves

A
  • atria to ventricle -> cuspid valves (atrioventricular valve)
  • bicuspid on left
  • tricuspid on the right
  • ventricle to artery -> semilunar valves
  • pulmonary semilunar valve on the right
  • aortic semilunar valve on the left
  • semilunar vales have 3 cups
  • valves are flaps of tissue
  • free edges of valves go into the ventricles
  • high pressure in ventricles -> closes the valves and prevents back flow
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23
Q

right atrium

A
  • deoxygenated blood enter the right atrium from the superior and inferior vena cava
  • walls of atrium are thin (myocardium)
  • less pressure is required
  • fossa ovalis- medial side of atrium wall -> important fetal blood circulation (flap fuses)
  • right atrioventricular valve- tricuspid valve -> goes to right ventricle
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24
Q

right ventricle

A
  • receives blood from right atrium
  • thicker walls
  • 3 major papillary muscles
  • corda tendinae- strings that close the valves when muscle contracts
  • papillary muscles contract and hold the corda tendinae tight -> closes bicuspid
  • semilunar valve opens to the pulmonary semilunar valve
  • trabeculae carneae muscles- in the wall of the right ventricle
  • less thick then the left ventricle
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25
left atrium
- oxygenated blood goes to left atrium via pulmonary vein - left and right pulmonary vein - thin wall - from left atrium to left ventricle -> bicuspid valve
26
left ventricle
- thick walls - trabeculae carnae in muscle wall - pumps blood to the aorta via aortic semilunar valve - papillary muscles and corda tendinae (string) prevent back flow
27
cardiac cycle
- defined based on contraction of ventricles - atrial systole (ventricular diastole)- atria contract - ventricular systole (atrial diastole)- ventricles contract 1. ventricular diastole- relaxed -> blood flow into atria 2. passive blood flow from atria to ventricle (80% due to pressure and gravity) 3. at the end of ventricular diastole (relaxation) -> atria contract -> push last bit of blood into the ventricles -> higher blood pressure in ventricles 4. ventricular systole- AV valves close -> ventricular contraction -> semilunar valves open 5. ventricular ejection- blood moves through the semilunar valves into the arteries 6. ventricles relax and the pressure in the arteries closes the semilunar valves 7. repeat
28
systole
- contraction of ventricles - closed AV valves - open semilunar valves - pumps blood into circulation - systole- allowing blood to pass into the arties
29
diastole
- relaxation of ventricles - closed semilunar valves - open AV valves - atrial compression pushing blood from atria into ventricles
30
lub
- as ventricles compress during systole -> closure of AV valves - systolic - AV valve close
31
dup
diastolic - semilunar valve closure - semilunar valves close due to pressure in arteries - beginning of diastole - relaxation of ventricles
32
sinoatrial (SA) node
- does not require active neural signaling - impulse starts here - beginning of impulse - contracts atrium - superior part of right atrium
33
atrioventricular (AV) node
- signal from the sinoatrial node - must pass here to atrioventricular bundle (lines of transmission) - within the cardiac muscle - branches to left and right - go to purkinje fibers - ventricles contract from inferior to superior
34
epicardium
- visceral layer of the serous pericardium - surrounds the heart - outer layer of the heart wall - areolar connective tissue and fat - binds the simple squamous epithelium -> producing the serous fluid
35
ventricular systole and diastole
-measure blood pressure
36
heart innervation
- dont need signaling to beat - sympathetic innervation- via vagus nerve -> increase in heart rate - parasympathetic innervation- via cervical sympathetic ganglion (superior in sympathetic chain) -> decrease heart rate - cell body is within sympathetic ganglion
37
coronary circulation
- pressure is too high and fast for heart - aorta -> left coronary artery -> anterior interventricular circumflex - aorta -> right coronary artery -> marginal posterior interventricular - great cardiac vein -> coronary sinus -> right atrium - small cardiac vein and middle cardiac vein -> coronary sinus -> right atrium
38
arteries
- blood pressure - away from the heart - branches get smaller - oxygenated in the systemic system - oxygenates the tissues - narrower lumen -> higher blood pressure - no valves - tunica media thickest (middle layer) - more elastic - elastic arteries (many elastic fibers) -> muscular arteries (more smooth muscle fibers) -> arteriole (< 6 smooth muscle layers)
39
veins
- adult circulation - towards the heart - branches get larger - deoxygenated in the systemic system - larger lumen - valves -> prevents back flow - required bc lower blood pressure - tunica externa thickest (outer layer) - less elastic - large vein -> medium veins (many valves) -> venule
40
capillaries
- pulmonary - systemic - portal systems - tiny - connect arteries to veins - just tunica intima - basement membrane of endothelium - precapillary sphincters RELAX between arterioles and capillary - blood flows into true capillaries - nutrients are delivered - 5-10 cycles per minute - precapillary sphincters CONTRACT - blood flows directly into veins - no nutrients delivered
41
layers of arteries and veins
- tunica intima- inner most: - endothelium (continuous with internal layer of the heart) - elastic tissue (especially for arteries) - tunica media- middle layer: - smooth muscle- reduce diameter and helps push blood through - regulates blood pressure and how much blood is going where - tunica externa- outer layer: - collagen and elastic fibers - nerves and lymphatics - vasa vasorum (blood vessels) -> helps oxygen and nutrients move from the artery to the tissues (especially for large arteries) -these layers are in veins and arteries
42
blood flow
-heart -> artery -> arteriole -> capillary -> venule -> vein -> heart
43
muscular artery
-have more smooth muscle compared to elastic artery (has more elastic)
44
what type of blood vessel is subjected to the highest blood pressure
- artery - left ventricle pumps blood into aorta -> has much thicker wall - large arteries are receiving the full pressure from the ventricle contraction - pressure decreases from there due to branching - specially the elastic arteries
45
arteriole
-< 6 smooth muscle layers
46
tunica intima of arteries
- endothelium - elastic tissue - allows for expansion and recoil -> maintain round shape - pressure reservoir -> aborb blood flow from the left ventricle of the heart without damage - acts with each ventricular diastole (relaxation) to propel blood -> allows for a continuous flow - elastic recoil continues to push blood forward during diastole
47
tunica media of arteries
- smooth muscles - affect blood pressure - contraction increases blood pressure - relaxation to decrease blood pressure -> increases blood to tissue - thicker within the arteries
48
structure of veins
- blood pressure is lower - fighting against gravity - skeletal muscle pump- staying active -> skeletal muscles surrounding will contract and increase pressure -> blood is pushed towards the heart - valves- as blood moves up the vein -> pressure fills up cups in valves -> avoids back flow - combination of valves and skeletal muscle pump pushes blood forward and prevents back flow
49
varicose veins
- some of the fluid is allows to back flow and pool - pooling of blood leads to high pressure in the veins - pushes plasma and fluid out - usually in legs or inferiorly - use compression socks
50
respiratory pump
- area surrounding the veins when there is high pressure -> pushes the blood upwards toward the heart - areas where there is low pressure will receive blood - action of the diaphragm - when diaphragm contracts -> increases the volume of thorax -> reduces the pressure -> low pressure in lungs -> increases pressure in abdomen -> pushes on veins -> pushes on veins in the abdomen towards the thorax - diaphragm relaxes -> smaller volume of thorax -> higher pressure in thorax -> low pressure abdomen -> pushes venous blood towards the heart
51
continuous capillaries
- lung - skeletal muscles - endothelial cells are touching each other - continuous cell membrane - gas can pass through but cells cant
52
fenestrated capillaries
- kidney- filtration - intestines- transmission of larger molecule nutrients - endocrine glands- hormones pass into blood - endothelial cells have holes in them - holes allow for the passage of fluid easily - larger molecules are dissolved in the fluid
53
sinusoid (discontinuous) capillaries
- liver - spleen- rbcs pass - red marrow- blood cells - fats and cells are passing through
54
blood pressure
- brachial artery on inner arm - larger arteries have higher blood pressure - sphygmomanometer - first beats- systolic pressure - beats stop- diastolic pressure - increase pressure in the sleeve until you cant hear -> stops blood flow - 120/80-140/90 - higher is hypertension -> caused by artherosclerosis
55
pulmonary circulation
- right ventricle -> pulmonary artery -> lungs - gas exchange between alveoli and capillaries - pulmonary arteries pass deoxygenated blood to capillary beds of alveoli - pulmonary veins bring oxygenated blood to the left atrium
56
which valve prevents blood in systemic circulation from flowing backwards into the heart
-aortic valve
57
anastamoses
- permit collateral circulation - collateral circulation- multiple parallel paths of circulation that start at the same point and end at the same point - smaller vessels can merge or go into larger vessels - circle of willis
58
portal systems
- 2 sets of capillaries connected by larger vessels (portal vein) - transports products to next region without being distributed by the heart (high concentrations) - if a product exists in the first capillary bed it will go to the second capillary bed in high concentration without being distributed anywhere else first
59
portal systems: hypothalamic-hypophyseal
- hepatic - nephronic - capillaries in- hypothalamus anterior pituitary (adenohypophysis)
60
hepatic portal system
- transmits from the capillaries surrounding digestive system towards the liver - filters products that are digested - maintains a high concentration of digested product from the digestion system to the liver before going to heart
61
nephronic portal system
- capillaries in glomerulus and peritubular capillaries | - associated with structures of filtration, reabsorption, and secretion
62
lymphatic system
- takes fluid from the circulatory system that is ejected - organ system - similar to and intimately associated with the cardiovascular system - returns interstitial fluid to blood stream - transport products of fat digestion - fats arnt filtered - filter foreign substances and dead cells from lymph in nodes and from blood in spleen - comprise part of immune system
63
four components of lymphatic system
- lymph - lymph vessels - lymph organs: nodes, spleen, thymus - diffuse patches of lymphatic tissue: tonsils and peyers patches
64
lymphatics: return interstitial fluid to blood stream
- capillary beds releases the fluid -> interstitial fluid- leaked fluid from capillaries - fluid builds up in the tissue surrounding capillary beds - no RBCs - no platelets - there are macrophages (phagocytes - there are lymphocytes (various leukocyte derived immune cells) - there are dissolved lipids (fat) - not the same as plasma - thin lymphatic vessels are directly associated and found with the capillary beds - lymphatics bring it back to the blood - lymphedema- swelling of tissue due to accumulation of interstitial fluid, often the result of lymphatic system blockage - treated with compression
65
lymph vessels
- capillary - lymphatic vessels - lymphatic trunk - lymph duct - go from the small vessels that merge into larger vessels until the lymph is dumped back to the subclavian arteries - capillary -> lymphatic vessels -> lymphatic trunk -> lymph duct -> subclavian veins - small -> large
66
lymph vessels: capillary
- smallest - larger diameter than the vascular capillary - they have closed ends -> no entrance - transmit the interstitial fluid from around the soft tissue of the capillary beds - intertwined with systemic capillary - go from the small vessels that merge into larger vessels until the lymph is dumped back to the subclavian arteries - in villi of small intestine -> lacteals - fat + lymph = chyle - too big to go into vascular capillaries - single layer of overlapping endothelial cells that are not totally fused - no basement membrane - adjacent cells can move apart from one another where they overlap (one way door) - high pressure in interstitial space "doors" push in (open) -> pushes interstitial fluid into the lymph capillaries - high pressure inside capillary "doors" push out (close) -> fluid retained within lymph capillary
67
lymph vessels
- larger diameter and more structure - overlapping endothelial cells - walls are thinner than veins - contains more valves than veins - pass through lymph node - afferent vessels (into nodes) - efferent vessels (out of node) - lymph nodes are strung along the lymph vessels
68
lymphatic drainage
- lymphatic drainage everywhere - entire body except: - CNS- although evidence of dural lymph drainage (has its drainage) - cornea - maybe teeth or bone - superficial structures- lymph vessel from superficial structures paths of superficial veins (axillary lymph nodes) - deep structures (except lungs)- lymph vessels from deep structures follow paths of arteries - lymphatic drainage of lungs follow tracheobronchial tree upwards - inguinal lymph nodes lie along internal, external and common iliac arteries (deep) - lymph nodes typically named for associated artery (deep)
69
which type of blood vessels would a lymphatic vessel draining the scalp likely follow
-superficial veins
70
lymphatic trunk
- trunks are paired (one both sides of body) - drain major regions of the body - jugular- head, neck (travels along jugular vein) - subclavian- upper limb, breast (travels along the subclavian vein/artery) - bronchomediastinal- thoracic organs - intestinal- abdominal organs - lumbar- pelvis, lower limb
71
lymph duct
- there are 2 - *thoracic duct- starts in cistern (intestinal and lumbar merge and drain) -> sometimes the bronchomediastinal - travels up to the left side of body - drains into the LEFT brachiocephalic vein - *right lymphatic duct- merging of the jugular and subclavian (sometimes the bronchomediastinal) - 1/3 of body drainage - drains into the RIGHT brachiocephalic vein
72
what lymphatic trunk would probably drain lymph from the right cheek
-right jugular
73
lymph flow: how does it move forward
- skeletal muscle contractions (like veins) -> increases pressure and valves prevent backflow - pulsation of adjacent artery- high pressure arterial flow (cyclical) running next to deep lymph vessels - intrinsic smooth muscle - overall pretty slow
74
lymph nodes
- filters lymph -> antigens and debris - immune response to antigens (tag them) - found in clusters so that lymph flows through multiple nodes (axillary lymph nodes) - medullary sinus- where lymph flows - cortex areas- maturation of immune cells -> fluid slows here and is filtered - lymphocytes = leukocytes -> mature here - response to antigens -> more lymphocytes and antibodies produced, antibodies bind to, tag, and help destroy antigen displaying cells - enlargement of nodes - afferent- lymph vessels are are flowing in - efferent- lymph vessels are flowing out
75
what direction is lymph flowing through an afferent vessel, relative to a lymph node
-into the lymph node
76
valves point
in the direction of flow
77
spleen
- largest lymph organ - monitors blood for antigens - similar to lymph nodes but for blood - site of erythrocyte phagocytosis - blood cell (formed element) reservoir) - erythrocytes reenter circulation when needed (exercise) - blood enters - filters plasma - efferent lymph vessels transmit filtered fluid into lymphatic system
78
thymus
- important at birth -> very important at puberty -> not so important adult - site of T-lymphocyte maturation before they are found within the lymph nodes - T-lymphocytes recognize antigens and start immune response - tag antigens and start immune response
79
diffuse patches of lymphatic tissues
- exposed lymphatic tissue - clusters of lymphatic cells not surrounded by connective tissues - pharyngeal tonsils- back of nasopharynx - palatine tonsils- back of oral cavity - lingual tonsils- posterior to tongue - filter debris that pass - sites where pathogens are collected and produce a immune response
80
peyer patches
- on the walls of small intestine - deep to villi - found within ileum - pathogenic microorganisms digested with food -> tagged and leads an immune response - diffuse patch of lymphatic tissue
81
respiratory system
- upper respiratory system: nasal cavity, paranasal sinuses, pharynx - lower respiratory system: larynx, trachea, respiratory tree, lungs and pleura - muscles of respiration
82
functions of respiratory system
- gas exchange - gas conditioning- maintaining moisture and temperature - sounds production - olfaction- bring gas towards olfactory neurons - defense
83
upper respiratory system
-nasal cavity, paranasal sinuses, pharynx | -
84
nasal cavity functions
- gas exchange- nasal breathing - gas conditioning- epithelial layer is covered in mucous (moisture) and capillaries (heat) - sound production- a resonance chamber for speech - olfaction- turbulence brings odorants to olfactory epithelium - defense- hairs and mucous trap particles and organisms
85
nasal cavity bones and paranasal sinuses
- bone- nasal, vomer, inferior nasal concha, lacrimal, palatine - bones with sinuses- frontal, sphenoid, ethmoid, maxilla - paranasal sinuses: - connected to nasal cavity - lined with nasal epithelium - common site of infection - no known function
86
pharynx
- nasopharynx- behind pharynx -> respiratory - oropharynx- behind oral cavity -> respiratory and digestive - laryngopharynx- behind larynx -> digestive - auditory tube- pressure in ears - soft palate- swings up and prevents fluid and bolus from being passed into the pharynx - epiglottis- cartilaginous, prevents food from going into respiratory - palataglossus- elevates tongue - palatapharygeus- elevates larynx and pharynx
87
pharyngeal epithelium
- cilia- can help sweep trapped particles in the mucous towards nasal aperture (away from pharynx) - stratified squamous epithelium multiple layers of cells ready to replace outer layer if it is lost - nasopharynx- pseudostratified ciliated columnar epithelium - oro- and laryngopharynx- non-keritanized stratified squamous epithelium - goblet cells- produce mucous
88
given what you know about epithelium which portion(s) of the pharynx are covered in stratified squamous epithelium
- laryngopharynx - oropharynx - associated with digestion so the scraping of food can tear away at layers of cells
89
wall muscles of pharynx
- constrict in sequence to force bolus of food into esophagus - superior constrictor - middle constrictor - inferior constrictor - constrict from superior to inferior - palatopharyngeus- swallowing muscle
90
nasal choanae
-nasal cavity opening
91
laryngeal inlet
-where air will move from the respiratory system into the larynx into the lower respiratory system
92
trachea
-transmits air to lungs
93
larynx
- cartilages - unpaired- 3: - thyroid cartilage- largest - cricoid cartilage - epiglottis- flap that covers laryngeal inlet - paired cartilages: - cuneiform- found in ligaments and soft tissue between epiglottis and other cartilages - arytenoid- largest of paired, critical for speech and sound, attached to vocal cords - corniculate- binds to ligaments and muscles for speech - pivoting of paired cartilages leads to opening or closing of vocal folds
94
vocal folds
- rima glottidis- area between vocal folds -> Changes pitch - vocal folds are epithelium covered ligaments that connect the thyroid and the arytenoid cartilages - vibrate -> sound - arytenoid and corniculate rotated towards midline (adduction) -> closing of vocal folds - lateral abduction -of arytenoid and corniculate> opening of vocal folds - increase tension of vocal cords (or smaller larynx) -> higher pitch - decrease tension of vocal cords (larger larynx) -> lower pitch
95
cricothyroid muscle
- connects the cricoid cartilage thyroid cartilage - elongates - increase tension of the vocal cords - pulls thyroid cartilage towards the cricoid
96
thyroarytenoid
- decreases tension | - relaxes vocal cords
97
arytenoideus
- pulls medially - adducts - closing vocal folds
98
lateral cricoarytenoid
- rotates - adduction - closing vocal folds
99
posterior cricoarytenoid
- abducts - opening vocal folds - rotates
100
trachea
- series of C-shaped cartilages - trachealis- smooth muscle posteriorly - sympathetic- relaxation of trachealis - parasympathetic- constriction of trachealis
101
tracheotomy
- incision is made superior to suprasternal notch - thyroid may have to be cut as well - incision from cricoid cartilage
102
respiratory (bronchial) tree
- 3 structural divisions: - bronchus: cartilage, muscle, glands - bronchiole: no cartilage, has smooth muscle, no glands - alveolar: no cartilage, no muscle, no glands - bronchus and bronchiole -> conduction - alveolar -> respiration
103
bronchi and trachea
- have epithelial tissue that contain goblet cells | - goblet cells secrete fluid to resist debris
104
bronchus and bronchiole
conduction
105
path of air flow
-primary bronchus (one for each lung) -> secondary bronchus (lobar bronchus) -> 3 right and 2 left -> tertiary bronchus (segmental bronchus) -> 10 right and 8-10 left -> bronchiole -> terminal bronchiole (respiratory bronchiole) -> alveolar duct -> alveolus
106
heart is more on left
-left lung is smaller
107
bronchogram
- shows fluid in bronchi - inflammation - airways become visible in x-ray when they are filled with something other than air
108
asthma
- in the bronchioles - in response to stress or environment - treated with coricosteriods - diamters reduce in diameter (not nervous system related) - inflammatory response - layers that are deep to smooth muscle lining of bronchioles - submucosa layer increases - mucousa epithelium increase -> prevents airflow - albuterol is used during an emergency
109
sympathetic
- relaxation of bronchus and bronchioles - bc these have smooth muscle - and trachea?
110
parasympathetic
- constriction of bronchus and bronchioles - bc these has smooth muscle - and trachea?
111
terminal bronchioles
- respiratory bronchioles - end in alveolar clusters - has smooth muscles - no cartilage - parallel to the arterial system
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alveolus
- air is brought into alveoli through the alveolar duct - but the alveoli are continuous and are also connected to each other - no cartilage, no muscle, no glands - surrounded by capillary beds - 3 cells types - macrophages are present- phagocytosis of debris - RBC's are present
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alveolar type 1 cells
- squamous - epithelial cell - allow gas exchange
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alveolar type 2 cells
- septal cell | - produce surfactant (protective fluid) -> moisture on cells so they dont stick
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gas exchange
- alveoli are pressed up against the capillary squamous epithelial cells (endothelial) - thin basement membranes and cell walls -> allow for gas exchange
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pneumonia
- fluid in lung - infection - leukocytes are present bc of infection and fluid - prevents gas exchange - treated with antibiotics
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right lung
- 3 lobes - 3 fissures - superior, middle and inferior lobes - oblique fissure- between superior and middle - horizontal fissure- between middle and inferior - esophagus, brachiocephalic vein
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left lung
- 2 lobes - 1 fissure - oblique fissure - superior and inferior lobes - cardiac impression- aorta, cardiac notch, subclavian artery, lingula
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pleura
- surround the lungs - double layered tissue - in between the pleura cavity is filled with the pleural fluid - parietal layer is touching the connective tissue (outer layer) - visceral pleura are touching the lung tissue itself (inner layer) - serous membrane - epithelial (produces the fluid) and connective tissue - lowers the friction - maintains surface tension
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inspiration
- diaphragm contracts - increase vertical volume - pressure decreases - air rushes in - pushes down on abdomen - nerve impulse - external intercostals are involved
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expiration
- diaphragm relaxes - decreases vertical volume - pressure increases - air rushes out - pushes back up into a dome - passive (no impulse or contraction)
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forced inhalation
- external intercostals - SCM- sternoclanomastoid - scalenes - pectoralis minor - elevates ribs - lateral dimension increased
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forced exhalation
- internal intercostals - abdominal muscles - ribs depressed - lateral dimension decreased - not passive
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innervation of respiratory system
- trachea and respiratory tree- autonomic (symp and parasymp) - pulmonary arteries- autonomic (symp and parasymp) - inhalation and exhalation- voluntary muscles (somatic motor) but rhythm is under unconscious control (brainstem) - unconscious breathing through somatic motor -> unconscious bc it picks up information from - receive signals from carotid arteries (innervated by glossopharyngeal nerve) -> pick up amount of O2 in blood - information from lungs - information from receptors
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bronchodilation
-sympathetic (synapse at paravertebral)
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bronchoconstriction
-parasympathetic (vagus)
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mechanism of breathing
- rhythmic neural stimulation from respiratory centers in brain stem - respiratory center for inhalation always active (neural stimulation) - respiratory center for exhalation only active during forceful exhalation (normally passive) - neural stimulation is absent for passive exhalation
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respiratory centers
respiratory centers in medulla oblongata and pons
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diaphragm innervation
phrenic (C3-C5)
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regulation of respiratory centers
- chemoreceptors of carotid bodies (CN IX) - aortic bodies (CN X) - unconscious increase in speed of respiration - chemoreceptors- detect O2, CO2 levels - limited voluntary control
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function of digestive system
- ingestion - digestion- mechanical and chemical - absorption- vascular capillaries and lacteals (lymphatic capillaries) - elimination
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GI tract
- oral cavity - pharynx - esophagus - intestines - where food moves through a single tube
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accessory organs of digestion
- salivary glands - enzymes that break down food - teeth - tongue - liver- filter and produce fluid for chemical breakdown - gal bladder- produce fluid for chemical breakdown - pancreas- produce fluid for chemical breakdown
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oral cavity
- salivary glands - ingestion and mastication - enzyme - part of GI tract - palate at top - tongue - bony alveolus - vestibule between lips and cheek - palatoglossal and palatopharyngeal arch -> swallowing - palatine tonsil - fauces- opening between the oral cavity and oral pharynx - uvula
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oral cavity, pharynx and esophagus
swallow
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stomach
digestion
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small intestine
digestion and absorption
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liver, gallbladder and pancreas
-enzymes
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large intestine
absorption and storage
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mastication
- mechanical digestion - orbicular oris- CN VII - buccinator- CN VII - masseter- CN V3 - medial pterygoid- CN V3 - temporalis- CN V3 - lateral pterygoid- lateral depression of jaw -> CN V3 - produces a bolis
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muscles of tongue
- palatoglossus- upward movement- CN X - genioglossus- CN XII - hypoglossus- backward and inferiorly- CN XII - intrinsic muscles- longitudinal and transverse- CN XII - styloglossus- CN XII - creates the bolus - fibers run longitudinal and transverse
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taste
- CN IX- posterior 1/3- glossopharyngeal | - CN VII- anterior 2/3 - facial (chorda tympani)
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sensation
- CN IX- posterior 1/3- glossopharyngeal | - CN V3- anterior 2/3- trigeminal mandibular division
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teeth
- 2 incisor- I1 and I2 - canine- C - 2 premolars- bicuspids -> P3 and P4 - 3 molars- tricuspids -> M1, M2, M3 - numbered from medial to lateral
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dentition
- crown morphology reflects function but all teeth have the same basic structure - between root and crown is the neck - enamel- mineralization - dentine - pulp- center of tooth - cementum- ligaments that bind the teeth to the bone - canal within the root- vascularizes
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salivary glands
- maintain moisture - chemical digestion- enzymes - mucus glands- mucin mixes with water to make mucus - serous glands- watery fluid with digestive enzymes - there are 3: - submandibular gland- serous, mucus, CN VII, 60-70% - parotid gland- serous, CN IX, 25-30% - sublingual- serous, mucus, CN VII, 3-5%
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swallowing
- starts in oral cavity - extrinsic and intrinsic muscles voluntary swallow - pharyngeal phase- (involuntary) soft palate will automatically rise to prevent bolus from going into nasopharynx, epiglottis moves down and over the opening to the larynx -> bolus enters the esophagus - esophageal phase- (involuntary) peristaltic contractions push the bolus downward
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pharnyx
- superior, middle, and inferior muscles - skeletal muscle - posterior to the oral pharynx - covered in epithelium and connective tissue - pharyngeal constrictor muscles constrict wall of pharynx during swallowing
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esophagus
- wave like smooth muscle contractions - push bolus towards stomach - long- from neck, behind trachea, through a hiatus in the diaphragm, into the abdomen - stratified squamous lines the esophageal walls
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esophageal hiatus
-opening in posterior diaphragm that allows esophagus into abdomen
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cardiac sphincter
- thickened ring of circular smooth muscles at inferior end of esophagus - contracts to make sure stomach fluid doesnt back flow into esophagus
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cardiac orifice
-connection between esophagus and stomach
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barret esophagus
-simple columnar cells
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simple columnar
- found in people with GERD - gastoesophageal reflux disease - stomach has simple columnar too
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components of the digestive system tubes
- mucosa: epithelium, lamina propria (connective, muscularis mucosae (muscle) - muscularis mucosae- increase the SA bc of folds - submucosa - muscularis externa: internal circular and external longitudinal - adventitia or serosa: advenitia (connective) and peritoneum (serous membrane)
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epithelium of mucosa
- stratified squamous epithelium: mouth, oropharynx, larynhopharynx, esophagus, anal canal - simple columnar: stomach, small and large intestine
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muscularis externa
- usually 2 layers - internal circular - external longitudinal - smooth muscle fibers except for: - skeletal muscle in oral cavity, oropharynx, laryngopharynx, upper portion esophagus, and external anal sphincter - innermost oblique layer (unique third muscle layer)- in stomach
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outermost layer
- adventitia (connective tissue) - serosa (adventitia with epithelial layer -> forms the peritoneum) - above the diaphragm- adventitia - below diaphragm: intraperitoneal (all serosa) and retroperitoneal (posterior to peritoneal -> mostly adventita)
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peritoneum
- a serous membrane - parietal layer (outer) - peritoneal cavity - visceral layer (inner)