Random Flashcards

1
Q

MND presentation

A

Upper and lower MN signs

no sensory involvement

Bulbar signs - tongue wasting, fasciculations

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2
Q

Hemisection of cord

A

Ipsilateral paralysis + loss of light touch/vibration

Contralateral loss of pain + temp

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3
Q

Cluster headache

A

More common in men
Unilateral, autonomic features
Px feel the need to move around

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4
Q

Amaurosis fugax

A

Curtain drawing over eyes

retinal a. embolism as a consequence of AF

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5
Q

Status epilepticus tx

A

Rectal diazepam -> intravenous lorazepam

No response? load urgently with phenytoin

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6
Q

Complex partial seizure

A

They don’t remember having it

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7
Q

Psoriasis nail changes

A

Onycholysis

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8
Q

Basal cell carcinoma main characteristic

A

Rolled edge

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9
Q

Squamous cell carcinoma characteristics

A

Hyperkeratonic, ulcerated nodules with inverted edges

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10
Q

Breslows thickness

A

Assesses the invasion of the melanoma starting from the granular layer of the epidermis to the deepest part

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11
Q

Negative D-dimer?

A

Pulmonary embolism

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12
Q

Genetics in burkitts lymphoma

A

t (8,14)

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13
Q

Rouleaux formation

A

Seen in multiple myeloma

RBC’s adhere and stack on each other

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14
Q

LSE anaemia?

A

Normocytic normochromic due to decreased erythropoeisis

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15
Q

Mccune albright syndrome

A

genetic disorder causing uncontrolled secretion of a number of endocrine glands

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16
Q

De quervains thyroiditis

A

transient change in thyroid status due to a viral infection

17
Q

Anion gap formula

A

(Na + K) - (Cl + HCO3)

18
Q

Familial gastric cancer mutation?

A

CDH1 (e-cadherin) mutation

19
Q

Hepatocellular carcinoma marker

A

Alpha feto protein

20
Q

Cirrhosis LFT findings and consequences

A

Rasied bilirubin and PT, lowered albumin and platelets

Ascites, encephalopathy, variceal bleeding, hepatocellular carcinoma

21
Q

Spontaneous bacterial peritonitis?

A

Ascitic tap >250 neutrophils

IV antibiotics and albumin

22
Q

Causes of dysphagia

A

Oesophageal carcinoma, oesophageal ring, peptic strictures, retrosternal goitre

23
Q

Difference between duodenal and gastric ulcer pain?

A

Duodenal pain normally relieved after meals, gastric worse.

24
Q

Oesophageal varices tx

A

B blockers

TIPPS 2nd line

25
Conditions predisposing to colorectal cancer
IBD, lynch syndrome
26
2 commonest causes of acute pancreatitis?
Alcohol, gallstones
27
Tx for massive haematemesis?
Fluid resusc Terlipressin Antibiotics
28
Goldstandard inv for suspected colorectal cancer?
Colonoscopy - permits biopsies + localisation of the tumour
29
Hereditary haemochromatosis initial tx
Venesection
30
Mallory weiss syndrome?
Oesophageal laceration. Forceful prolonged vomiting and haemetemesis
31
Hereditary nephritis, sensorineural deafness and occular abnormalities point to what?
Alport syndrome - genetic defect in type IV collagen
32
Wolfram syndrome?
Can cause DI, DM, optic atrophy and deafness Glucose would be detected on urine dipstick
33
Most common sx of bladder cancer?
Painless haematuria with weight loss
34
What are abdominal bruits highly suggestive of in renal?
Renovascular disease