Reactive Oxygen Species

Question 1

NADPH Oxidase

Answer 1

Converts molecular oxygen to superoxide

Question 2

Superoxide dismutase

Answer 2

Converts superoxide to hydrogen peroxide

Question 3

Myeloperoxide

Answer 3

Using Cl-, converts hydrogen peroxide to Hydroxyl-halide radicals (HCLO)

Question 4

Gluathione peroxidase

Answer 4

Using selenium, converts hydrogen peroxide to water while producing glutathione disulfide

Question 5

Glutathione reductase

Answer 5

reduces NADPH

Question 6

Glucose-6-phosphate dehydrogenase (G6PD):

Answer 6

regenerates NADPH and converts glucose-6-phosphate to 6-phosphogluconolactone