Regal-Summary of actions of inflammation mediators Flashcards Preview

IHO Week 6 > Regal-Summary of actions of inflammation mediators > Flashcards

Flashcards in Regal-Summary of actions of inflammation mediators Deck (15)
Loading flashcards...
1

What inflammatory mediators cause vasodilation--> redness?

Histmaine
PGE2
PGI2
kinins

2

What inflammatory mediators cause increased vascular permeability--> swelling?

Histamine
petido leukotrienes (LTC4, LTD4, LTE4)
kinins

3

What inflammatory mediators cause pain?

PGE
PGI
LTB4
Kinins

4

What inflammatory mediators are chemotactic (direct migrations of WBC)?

LTB4 (neutrophils)
petptidoleukotreines (eosinophils)

5

What inflammatory mediators cause fever?

PGEs

6

What inflammatory mediators cause airway constriction= bronchoconstriction?

Histamine
peptido leukotrienes
kinins
PGD2

7

What inflammatory mediators cause hypotension (shock)?

Kinins
Histamine

8

What does histamine do?

redness
heat
swelling
airway constriction
NOT chemotaxis

9

What do PGE2 and PGI2 do?

Increase vascular permeability
vasodilate
cause pain

10

What do PGD2 and thromboxane do?

vasoconstriction

11

What does TXA2 do?

platelet aggregation
vasoconstriction

12

What does PGI2 do?

Oppose platelet aggregation
vasodilation

13

What does LTB4 do?

Chemotactic (PMNs)
reduces paint threshold

14

What do peptidoleukotrienes do?

bronchoconstriction
increased vascular permeability
chemotaxis

15

What do kinins do?

EVERYTHING

strong vasodilator--> HYPOTENSION