Renal Flashcards
Which syndrome causes hypomagnaesaemia ? Gittleman or Bartter’s
Gittleman’s
Where do Liddle, Barter and Gittleman’s syndromes affect the kidneys?
BGL
B - thick ascending limb
G - DCT
L - collecting ducts
Is renin and aldosterone high or low in liddle syndrome
low
what is the triad with which interstitial nephritis presents
fever, arthralgia and rash with renal impairment
Is there low or high eosinophils in acute interstitial nephritis
high - eosinophilia
how do you distinguish ATN and pre kidney disease in urine osmolality and urine sodium
ATN - low urine osmolality
PKD - high urine osmollality
ATN - high urine sodium
PKD - low urine sodium
which chromosome is mutation for ADPKD found?
1 = 16, 2 = 4
what abnormality is associated with BPH on PR exam
no loss of lateral sulcus on PR . Obliteration of sulcus occurs with prostate ca
what type of rTA is associated with AI diseases 1 or 2
1
What findings are there in kidney biopsy in diabetic nephropathy?
GBM thickening, mesangial expansion and arteriolar hyalinosis
What conditions would you tend to see associated with tubular atrophy?
renal artery stenosis, chronic reflux and chronic pyelonephritis
what effect does endothelin-1 have on blood vessels
potent vasoconstrictor. agonism of b1 endothelin receptor leads to vasodilation, naturesis and diuresis
most common side effect of amlodipine. headaches or angioedema?
headaches (more common that with other CCBS
which diuretic is associated with erectile dysfunction?
thiazide (also beta blockers)
Where is calcium reabsorbed
Distal convoluted tubule
