repro pharm

Question 1

name a synth progesterone used to chemically castrate hypersexual dogs

Answer 1

delmadinone

tardak

Question 2

name a progesterone r blocker

Answer 2

Aglepristone

Question 3

name a syn progesterone used to sync horses and pigs

Answer 3

altrenogestt/regumate

Question 4

what are the adverse effect of prog tx?

Answer 4

endo hyperplasia
endometrirtis
pyometria
inhib id ACTH
behavoural changes
DM

Question 5

what are the efffects of prog

Answer 5

inc mammary growth
inc luteal phase
no oxytocin R
anabolic effects

Question 6

where secretes prog

Answer 6

CL
placenta
adrenal cortex

Question 7

what is the most potent endog oestrogen

Answer 7

oestradiol

Question 8

what is a oestrog synth used to treat spay-related incontinence

Answer 8

oestriol

Question 9

where is oestrogen secreted from

Answer 9

ovaries (granulosa cells)
placenta
testes (sertoli)
adrenal cortex

Question 10

name 2 androgen inhibitors

Answer 10

finasteride

osaterone

Question 11

what are the adverse effects of androgens (testosterone basically..)

Answer 11

infert
oligospermia
perineal hernia
butch females
hepatox

Question 12

name a synth androgen which is a strong anobolic steroid

Answer 12

nandrolone

used in renal failure of cats

Question 13

name a synth androgen

Answer 13

danazol

immune mediated disease

Question 14

where are androgen released from

Answer 14

zona reticularis

Question 15

where is prog secreted from?

Answer 15

CL

Placenta

Question 16

where is test secreted from

Answer 16

ledig cells

theca cells

Question 17

what is the effect of oxytocin?

Answer 17

inc myometrial contraction
milk let down
may cause dystocia

Question 18

when are oxytocin R availbale

Answer 18

high oest

low prog

Question 19

name a prolactin inhib

Answer 19

Cabergoline (galastop)

induce oestrous and tx false preg

Question 20

why can oxytocin and ADH be released together

Answer 20

release of both is controlled by same nuclei and from the post pit

Question 21

what stimulates milk let down

Answer 21

oxytocin release which is stim by tactile, visual and auditory stimuli

Question 22

lactogenesis is

Answer 22

endocrine control of birth and let down

Question 23

galactoopeisis s

Answer 23

production of milk

Question 24

what need to happen for galactopoeisis to contineu

Answer 24

suckling

Question 25

name synth GnRH

Answer 25

gonadorelin

Question 26

name a GnRH agonist used in mares

Answer 26

deslorelin

Question 27

what can GnRH intervention do

Answer 27

``` manipulate follicular waves induce ovul synch oestrous control luteal phase stim ovarian activity advance oestrous induce parturition misalliance suppress repr (cat, dog and horse) ```

Question 28

what stimulates puberty

Answer 28

GnRH pulse gen inc freq

Question 29

how can you induce superovulation?

Answer 29

FSH inj (procine extract)

Question 30

when do endometrial cups appear?

Answer 30

d40-120 of preg

Question 31

what do endometrial cups produce?

Answer 31

eCG

Question 32

why would an injection of hCG be useful in suspect cryptorchid? (hint: it has a LH-lik effect)

Answer 32

will cause a rise of testosterone in the blood

Question 33

what type of effect does eCG have FSH-like or LH like?

Answer 33

FSH

Question 34

what is apotential SE of GnRH inj?

Answer 34

anaphylaxis, interspecies samples

Question 35

name a recomb PGF2a

Answer 35

Dinoprost

Question 36

name a synth PGF2a

Answer 36

colprostenol

Question 37

what is the action of PG on the luteal phase

Answer 37

shortens it

Question 38

how can GnRH be used to effect the luteal phase

Answer 38

it can tighten the timing of ovulation | as whilst PG is causing luteolysis, stim GnRH causes FSH and follicular dev therefore ovulation

Question 39

clenbuterol relaxes smooth muscle, what adreno-R does it agonise?

Answer 39

B2 | used to reduce myometrial contractions and dilate airways

Question 40

when would a reduction in myometrial contraction be useful?

Answer 40

dystocia and malpresentation of calves

Question 41

why would melatonin help oestrous synch

Answer 41

will inc or dec GnRH in seasonal breeders, may be able to advance breeding season - THOUGH only if everything else is 100% fine

Question 42

at term how can parturition be induced>

Answer 42

g-corticoids | PGs

Question 43

what animal can be induced by oxytocin

Answer 43

mares only