export_cnslp lectures (1) Flashcards

(51 cards)

1
Q

Name the 3 hypothalamic regions

A
  1. CD = Mammillary
  2. Intermediate = tuberal
  3. R = chiasmatic

Supraopt & Preoptic

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2
Q

What is the purpose of the CD hypothal group?

A

mamm bodies

smell

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3
Q

what is the fct of the intermediate group?

A

connect post pit gland to infundibulum.

VMH, DMH, ARC, LHA

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4
Q

What is the fct of the supraoptic nuc?

A

PVN & SON go to post pit gland, AHN and SCN

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5
Q

what is the fct of the preoprtic?

A

part of the hypothalamus

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6
Q

What nuclei control GI stim

A

dorsomed nuc

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7
Q

Where in the hypo is hunger and satiety controlled?

A

hunger - lateral hypo area

satiety - ventromed

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8
Q

What is the paraventricular nucleus responsible for?

A

Oxytocin release and water conservation

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9
Q

What is the supraoptic chiasmic nuc job?

A

ADH release

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10
Q

how do hypothalamic hormones arrive at pit gland

A
  • ANT pit = n-horm into cap (1) then pituitary hormones released into cap (2) = portal venous system
  • POST pit = n-horm into cap
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11
Q

what hormones are prod by the ant pit?

A

FLAT PiG

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12
Q

what is the role of the mamillary bodies?

A

smell and feeding

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13
Q

what is themain role of the nuclei in the tuberal/intermediate region of the hypothal?

A

feeding

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14
Q

where is temperature regulation in thehypo?

A

supraoptic chiasmic area, in AHN

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15
Q

what area controls cardiac fct?

A

preoptic chiasmic

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16
Q

what is the periventricular nuclei role?

A

fear, reward…

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17
Q

what is the purpose of the limbic system?

A

homeostasis
motivation

emotion

(inc olfaction)

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18
Q

What are the main componants of the limbic system?

A

hippocampus; hypothal; amygdala; basal ganglia; anterior thalamic nuc and paraolfactory

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19
Q

what is the reticular formation?

A

sensory info being recieved prevents sleep. RF in brainstem by pons and projects into cerebral cortex

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20
Q

if the LHA (later hypoth area) is lesioned, what happens?

A

stupor and cataplezy

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21
Q

where is orexin produced?

22
Q

what is orexin?

A

causes arousal and waking. R found extensivley.

23
Q

what are the 2 pos causes of narcolepsy?

A
orexin R abnormality (LAB)
abnormal orexin (dobies)
24
Q

Appeitie sensors inhibit satiety, T or F?

25
what is the glucostat theory?
that hunger depends on blood glucose. eg hunger = high, then bglucose will be low
26
what is the lipostat theory of appetite?
fat produces leptin which has R in brain. HIgh leptin = high fat = fat needs to decrease
27
Does leptin stimulate neurones which inhibit or stim feeding?
Inhibits
28
Eating i sassoc with dopamine release. Why does obesity lead to desensitisation?
Inc Dopam release, causes decreased number of receptors
29
NAme the 3 lobes of the cerebellum
Rost Cd (both = motor control) Flocculonodular (balance)
30
What is the main purpose of the cerebllum?
refine movement balance coord
31
what are the pyramindal tracts involved in?
skilled learned vol
32
what are the extra-pyramidal tracts involved in?
invol antigravity posture
33
hw does the cerebellum act to amend improper movenment
fback to red nucleus (EP tract) thalamus LMN --> not as efficient with rapid movement (practice)
34
What is the cerebellum, pyramida and extrapyramidal tracts part of?
UMN groups
35
Perkinje axons, in the arbor vitae synapse where?
deep cerebellar nuc in deep grey matter
36
what do the cerebellar peduncles do?
Cd - afferent --> cerebellum (vestib, proprioceptors) Mid - UMN from cerebr cortex --> cerebellum Cr - Efferent from cerebell --> red nuclei and thalamus
37
what is learning?
change in behaviour --> reward or avoidance
38
what are the 2 forms of memory
declarative | procedural
39
where is STM help?
hippcampus
40
where is LTM help?
cerebral cortex
41
where is working memory held?
prefrontal cortex
42
whatis cognition?
ability to think and plan and make behavioural changes
43
why is aggression seen in CDS?
imbalance of 5HT and ACh
44
what are the 3 main neuro-biological causes of Alzeimers?
1. brain atrophy 2. B-amyloid plaques 3. N-fibrillary tangles
45
describe the process of neurogenesis
* ventricular zone (stem cells) * cell bodies --> grey matter * axons --> white matter of marginal zone * diffferentiate
46
what stimulates n-genesis?
enrichment brain activity
47
where is balance control based in cerebellum?
flocculonodular lobe
48
what is NPY
appetite stim, LHA mainly
49
what is melanocortin
appetite suppressant
50
what is adiponectin?
released by fat cells in skinny animals to stim feeding
51
where are leptin R ?
arc nucleus