Resp Infections Flashcards

(27 cards)

1
Q

Common causes of

Common cold VS pharyngitis VS sinusitis

A

VIRAL for both

CC #coryza - rhinov

Pharyngitis - Rhino, Entero, ADeno

Sinusitis - viral > bact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Common causes of tonsillitis VS otitis media

A

Tonsillitis
2/3 - viral - EVV
1/3 - bacterial - strep A

Otitis media
Viral - RSV + Rhino
Bacterial - H. Influ + Moraxella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What’s wrong with these kids?

Kid comes in with nasal discharge and blocked nose. DX?

Kid comes in with sore throat. ENT examination = soft palate and tonsils inflamed

Kid comes in with fever headache malaise, inflamed tonsils with exudates and cervical lymphadenopathy

Kid comes in with a fever, if pain – kid tugs at affected ear. At otoscope equals red inflamed tympanic membrane. what reflexed does he lose?

Kid comes in with unilateral hearing loss, at otoscope = tympanic membrane is dull and retracted some fluid is visible.

Kid comes in with pain swelling and tenderness over zygomatic cheek area.

A

Common cold

Sore throat – pharyngitis

Tonsillitis

Acute otitis media - The loss of light reflex

Otitis media with effusion a.k.a. glue ear

Acute sinusitus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tx for cold?

Tx for pharyngitis and tonsillitis? How long for and why? Why should amoxicillin be avoided?

Tx for AOM? Effect of antibiotics?
Why do most kids suffer from otitis media?

Most common cause of conductive hearing loss in children? It’s effect?
Tx for OME/glue ear?
What surgery could be beneficial?

Tx for acute sinusitus?

A

Cold – symptomatic – paracetamol ibuprofens

Pharyngitis/tonsillitis – antibiotics EVEN THOUGH only a third infections = bacterial!!!
10 day treatment to remove risk of rheumatic fever.
Avoid amoxicillin = can cause maculopapular rash if tonsillitis is due to EBV

80% of AOM resolves spontaneously BUT Pain=paracetamol/ibuprofen
Antibiotics reduce pain duration BUT do not reduce risk of perforation –> hearing loss
Kids get OM because of short eustachian tube during childhood development

Common cause of conductive hearing loss and kids = O. media with fusion – glue ear
Conductive hearing loss results in delayed development of speech and learning
Use of GROMMET ensures eustachian tube remains patent to allow fuller hearing
Adenoidectomy because adenoids harbour infection that spread to Eustachian tube. Between the years 2–8 adenoids go proportionally faster than airway – > narrow airway lumen occurs then.

Symptomatic – paracetamol/ibuprofens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the main features of laryngeal and tracheal infections?

Common and rare causes?

A

Think about what organs are present in neck:
Vocal chords – horse voice
Trachea – stridor, barking cough, dyspnoea

Causes:
Croup – viral laryngotracheitis//bacterial tracheitis
Rare – epiglottitits//inhaled foreign body//diphtheria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How to assess severity of laryngeal and tracheal infection?

How do you manage acute upper airway obstruction? What not to do?
If severe? If resp failure develops?

A

SUBCOSTAL, intersternal, sternal recession
Cyanosis, tachycardia, low O2 SATs, agitation

NOT THROAT - can cause complete obstruction
Reduce anxiety – stay calm & look for signs of hypoxia

Severe – nebulised epinephrine
At respiratory failure - INTUBATE + anesthetist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Difference between croup and bacterial tracheitis?
Most common cause of croup?

Common age groups? Peak incidence age?

Treatment for croup?
Treatment for severe croup?
Which healthcare professional needs to be on board?

A

Croup is viral tracheitis; BT is because of bacteria…
RSV, influenza

6m–6yrs; Peak = 2 years

Keep child calm – avoid upsetting
Oral steds - dexamethasone +prednisone
Neb steds - BUDESONIDE

Severe- Nebulised epinephrine + oxygen

Call Anaesthetist if deteriorating due to risk of rebound symptoms once epinephrine diminishes after 2 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How does bacterial tracheitis differ from viral tracheitis (aka croup)?

Aetiology?

Treatment?

A

Child has high fever
Appears toxic
Rapidly progressive every obstruction due to THICKER airway secretions

Viral doesn’t have that shit

Staph aureus

IV antibiotics
intubation/tracheostomy + ventilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What causes acute epiglottitis aetiology?

What exactly happens to the tissues?

What age group most common?

Difference between croup and epiglottitis in terms of:
Appearance/fever
Breathing stridor/Boice
Cough/Coryza
Drink/Drool
A

H influenza

Massive swelling of epiglottis and septicaemia

1–6 years

Appearance: Croup – unwell; Epiglottitis - toxic
Fever: Croup - <38.5; Epiglottitis - >38.5

Strider: Croup - HARSH RASP; Epiglottits - SOFT WHISPER
Voice: Croup - hoarse; epiglottitis - muffled sound

Cough: croup - BARK; epiglottitis - minimal
Coryza: croup - YES(like viral colds); epiglottitis-NO!!

Drink: Croup - yes; Epiglottitis - no
Drool: Croup - no; epiglottis - yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Treatment for epiglottitis? What NOT to do?

Prophylaxis?

A

Do you not lie kid down; examine throat with spatula —— precipitate total of obstruction = death

Call anaesthetist, ENT, paediatrician – ICU transfer

Intubate/tracheostomy – >
THEN DO blood culture + IV antibiotics cefuroxime

After 24 hours remove tracheal tube
Antibiotics 3 to 5 days

Prophylaxis – rifampicin household contacts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Aetiology of whooping cough VS bronchiolitis?

Signs of whooping cough?

What can occur during spasmodic phase?

Complications of whooping cough?

Investigations or whooping cough

Treatment and prophylactics treatment?

Effects of vaccination?

A

Bordetella pertussis - whooping cough
RSV - bronchiolitis

CORYZA COUGH WHOOP
Catarrhal Coryza -> spasmodic coughing – > inspiratory whoop

Vomit, nosebleed, subconjunctival haemorrhage

Pneumonia bronchiectasis; sleep apnoea

FBC – increased white blood cells
Nasal swab

Admit to hospital
Antibiotics – erythromycin
Prophylactic erythromycin for close contact

Does not provide immunity – only reduce risk of contracting condition and severity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Aetiology of whooping cough VS bronchiolitis?

In whom and when?

Pathophysiology?

A

Bordetella pertussis - whooping cough
RSV - bronchiolitis

Less than 12 months – autumn and spring

Inflammation of bronchioles #EpithelialNecrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Symptoms of bronchiolitis

Signs of bronchiolitis?

Signs and symptoms of bronchiolitis on examination

Investigations?

Treatment?

Complications?

A

Cough and coryza – >
Difficulty breathing + poor feeding

Inspection: –
Hypoxia
Increased work of breathing (tachypnoea / tracheal tug/ subcostal recession)

Palpation – downwardly displaced liver

Auscultation – crepitations and wheeze

PCR from nasopharyngeal secretion – RSV
CXR – hyperinflation lungs
Blood gas – low O2; high CO2

Supportive – O2; NG/IV fluids&feeds; CPAP
Palivizumab = prophylaxis - reduce risk of hosp admission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Risk factors for pneumonia?

Signs? Symptoms?

Treatment?

Investigation?

Complications?

A

Low-birth-weight
Vitamin a deficiency
Not breastfed

Signs:
Mouth – cyanosis and tachypnoea
Inspection – increased work of breath (subcostal recession): bronchial breathing; accessory muscles
Palpation/Percussion: Consolidation dull
Auscultation: crepitations bronchial breathing

Symptoms:
Fever shortness of breath productive cough
Pleuritic chest pain (neck, chest, abdominal pain)

BAP
Breathing – maintain SATS O2
Antibiotics – Amoxicillin
Pain – analgesia

Investigation – sputum & blood culture MCS
FBC – raised WCC
CXR – infiltrates

Resp failure – >ARDS
Empyema
Septic shock – >hypotension
Pleural effusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ax pneumonia?

A

Kids: viruses; strep pneumonia; Mycoplasma

Community and hospital:
Strep pneumonia, H. influenza, staph aureus

Immunodeficient:
PCP, staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Give 4 causes of wheeze

Pathophysiology of asthma?

A

Congen – CF; lung heart abnormality;
Infect/immune - atopic IgE ASTHMA
Cancer – there is none
Environ – inhale foreign object; aspiration of feed

Allergen – >TH2 cells – >

Stimulates IL-4:
Stimulate B cell –>
make IgE -> mast cell degran + release histamine -> b.constriction

Stimulates IL-13: stimulate mucous secretion

17
Q

Take a history of asthma patient

A
O: when? How long?
T: how often? Come and go/sudden?
E: triggers?!
Cold air/exercise
Dust
Pollen/chemicals
Day VS night
Work VS home(school) -> sport affected 

PMH of atopy
Dx – asthma treatment makes better?//ALLERGIES
Fx – of atopy
Sx - ADL; pets allergy; travel

18
Q

Examination of chronic asthma

A

Peripheral – finger clubbing (CF/bronchiectasis – chronic condition)

Eyes and mouth – cyanosis; wet cough/horse voice; sputum

Chest – tightness/tachycardia/tachypnoea

Inspection – hyper inflation//HARRISON SULCI

Auscultation – wheeze

19
Q

How to ask parents how well controlled kids asthma is

A

Severity-frequency of symptoms-exacerbation
Hospital admissions for exacerbation
School Time off//exercise limitations//smoking exposure
How Often use inhaler//inhaler technique//oral steroid use
Peak flow diary//sleep affected

20
Q

Steps for chronic asthma control

How to treat exercise-induced-asthma and aspirin-induced-asthma?

A
  1. SABA reliever - mild intermittent
  2. +Beclametasone - inhaled sted - regular preventer
  3. Add-on therapy
    <2yrs - RESP DOC
    <5yrs - Montelukast/Theophylline
    >5yrs - + LABA (Montelukast if LABA doesn’t work)
  4. Persistent poor control - Increased BECKY!! Max dose recommended
  5. Continuous use of oral steds Prednis //RESP doc//immunosupp

Exercise induced –
SABA before exercise
Becky + LABA if symtopms worse

Aspirin induced – montelukast

21
Q

How would you assess the following asthmas?

12-year-old kid PEFR >50%; SATS > 92%; no clinical signs of asthma

12yr old Kid with PEFR 33–50% predicted
Sats<92%;
Can’t complete sentence in one breath; use of accessory muscle
RR >25; HR > 110

12yr old Kid with PEFR <33% predicted
Sats<92%;
Confused; bradycardic; hypotensive; auscultation can’t hear chest
RESP ACIDOSIS - low pH; low HCO3; high CO2

A
  1. Moderate
  2. Severe
  3. Life threatening
22
Q

How to treat a moderate, severe, life-threatening asthma?

What to do if not responding?

If responding?

A

Moderate – > SABA up to 10 puffs

Severe ->
OSHIT - O2 (cos sats<92%), SABA, Hydrocortisone, Ipratropium, Theophylline

Life-threatening – > OSHIT+seniorDoc

Moderate/Severe/Life threatening–>
Assess RR/HR/PEFR/SAT’s

Not responding?
Sent to HDU/PICU;
Ix: CXR // PEFR// blood gas if <92%
Tx: IV MgSO4 bolus // IV aminophylline

Responding?
Continue bronchodilation + Oral STEDS 3days

23
Q

How to assess patient education on asthma?

How to assess how well controlled asthma is?

A

What do if asthma gets worse?
What drugs do? Reliever VS preventer

When to use drug?

How often use inhaler frequency VS dose?
How to use inhaler technique?

24
Q

What is bronchiectasis?

Causes?

Pathophysiology?

A

Permanent dilation of Airways due to inflammation and inability to clear secretion

Congenital: CF / Kartagener syndrome
Infect/immune: IBD; rheumatoid arthritis
Environment: smoking

Cause –> infection of small distal away –> inflammation release inflammatory mediators –> ciliary reaction impaired ->
bacterial proliferation + tissue damage – > bronchodilation

25
Genetics of CF? Type of ppl? Incidence and carrier rates in Caucasians? What does CFTR do? Pathophysiology of CF?
AR CFTR gene defect @chromosome 7 Mostly for genetic disease and Caucasians 1/2500 incidence; 1/25 carrier rate in whites CFTR codes for ATP induced Cl- channel which secretes Cl- into lungs and GI tract & absorb Cl- from sweat CFTR mutation –> misfolded Cl- channel -> Hence high intracell Cl- cos it cant be secreted into lungs and GI tract -> Compensatory Na reabsorb from Na channels -> Water follows sodium into cells -> leaving thick mucus out in Lung and GI tract High Cl- in sweat glands
26
CF Screening? Diagnosis? Ix? CF Symptoms? Signs on Examination?
Screening: IRT ImmunoReactive Trypsin on Guthrie Diagnosis: SWEAT TEST FaECAL ELASTASE CXR: bronchiectasis hyperinflation Sputum culture: Strep pneu; H. Influ; Staph Aur PSEUDOMONAS AND CEPACIA between CF patients #DONTSOCIALISE!!! Bloods: FBC, LFT, CRP, ESR Gene studies ``` Symptoms: lung and GI issues... Lung: chest infections = FEVER COUGH persistent SPUTUM purulent; ``` GI: steatorrhoea; malabsorption; poor growth ``` Signs Exam: Peripheral: CLUBBING #chronic Nose: nasal POLYPSSSSS!!!!!! Inspect: hyperinflation Auscultation: CREPS/ exp WHEEZE ```
27
``` Treatment for CF? ABC D2(think bates motel) EFS ``` Complications of CF?
Antibiotics Bronchodilators Corticosteroids Drainage postural/percuss/deep breaths - PHYSIO DNAase decrease viscosity Enzyme supplementation pancreatic Food= HIGH calorie overnight gastrotomy-fat sol vits Surgery – lungs and heart transplant ``` Intest/panc/liver + balls Thick ASS mucus -> Meconium ileus; distant intestinal obstruction #GASTROGRAFFIN Pancreatic insufficiency / Diabetes Hepatomeg cos of impaired bile flow Infertility in males - vas def absent ```