Review 7 Flashcards Preview

Biochem, Nutrition, Genetics > Review 7 > Flashcards

Flashcards in Review 7 Deck (18):
1

Fatty acids in membrane lipids (8)

Myristic acid
Palmitic acid
Pamitoleic
Stearic
Oleic
Linoleic
Linolenic
Arachidonic

2

Myristic acid

14 carbons, saturated

3

Palmitic acid

16 carbons, saturated

4

Palmitoleic acid

16 carbons
Cis unsaturated at
(9)C=C(10)

5

Stearic acid

18 carbons, saturated

6

Oleic acid

18 carbons
Double bond C9-10

7

Linoleic acid

18 carbons
C9=10
C12=13

8

Linolenic acid

18 carbons
C9=10
C12=13
C15=16

9

Arachidonic acid

20 carbons
C5=6
C8=9
C11=12
C14=15

10

Fatty acids in membrane lipids with 16 carbons

Palmitic and palmitoleic acids

11

Fatty acids in membrane lipids with 18 carbons (4)

Stearic
Oleic
Linoleic
Linolenic

12

Trans double bond

Left side; stiffer

13

Cis double bond

Right side; kink in tail

14

Aquaporins

Allow water and some solutes to cross membrane

6 alpha helices

10 different tissue specific family members (rbc, brain, eye, kidney, lung etc)

15

Cystic fibrosis

Caused by mutation in Cl- transporter (CFTR)

Caused downstream alteration in fluid movement across membrane

16

HYPP

Hyperkalenic periodic paralysis

AQH
Mutation in skeletal muscle Na+ channel
Gating and proper closure

17

Uric acid

End product of purine metabolism

Converted to allantoin in liver prior to excretion - transporter from blood to sub cellular site of enzyme uricase

Uric acid + uricase = allantoin

18

Dalmatian mutation in uric acid transporter

SLC2A9

Hyperuricosemia, hyperuricosuria, and stones

Crystallization of insoluble excess uric acid in urine