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Flashcards in Review Power Point Deck (123)
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1

What 3 things make up ground substance?

Glycoproteins
Glycoseaminoglycans
Proteoglycans

2

Ground substance participates in binding cells to fibers of what?

Fibers of connective tissues

3

What is a glycoprotein?

A protein with 1 or more attached sugars

4

GAGs are a family of what?

Heteropolysacharides

5

What are 2 important characteristics of GAGs?

Very hydrated
Very negative

6

What makes up proteoglycans?

A protein core with many GAG side chains
(Bottle brush)

7

What makes and secretes the large majority of extracellular matrix?

Neighboring cells

8

What is the most common cell of connective tissue?

Fibroblasts

9

What cells secrete dentin?

Odontoblasts

10

What cells secrete enamel?

Ameloblasts

11

What is the structure of tropocollagen?

3 helical strands

12

How do tropocollagen fibrils arrange themselves?

In a staggered array of parallel bundles

13

What causes striations in tropocollagen?

The alignment of every 4th molecule

14

Tropocollagen crosslinks via what?

Lysinonorleucine

15

Production of lysinornorleucine requires which enzyme?

Lysyl amino oxidase

16

What cofactor is needed for lysyl amino oxidase?

Vitamin B6 (pyridoxine)

17

What types of collagens are found in interstitial connective tissue?

Types I, II, III, V, XI

18

What is the most abundant collagen type

Type I

19

Most connective tissues have which collagen type?

Type I

20

What are some examples of tissues containing type I collagen?

Bone
Tendon
Skin
Dentin
Ligament
Fascia
Arteries
Uterus

21

Type II collagen is a component of what type of cartilage?

Hyaline cartilage

22

Where is the 1 optometry correlation of type II collagen found?

In vitreous humor

23

Reticular fibers are made up of which collagen type?

Type III

24

Where are 3 places that type III collagen is found?

Skin
Arteries
Uterus

25

What is the predominant collagen type in periodontal ligament?

Type III collagen

26

T/F Type III collagen is often found in bone.

False

27

Which collagen type is the most abundant structural component of basement membranes?

Type IV

28

The lens has which collagen type?

Type IV

29

What makes type VIII collagen?

Endothelial cells

30

What makes type X collagen? When does this occur?

Chondrocytes
During endochondral ossification