RRD #4 Flashcards

(70 cards)

1
Q

Infectious diseases

A

disorders in which tissue damage or dysfunction is produced by a microorganism

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2
Q

endemic

A

used to describe a disease that exists all the time in certain
communities

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3
Q

epidemic

A

—an outbreak of a disease that spreads within a certain time frame
to people of one or several communities

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4
Q

pandemic

A

the disease outbreak spreads from being epidemic (a few

communities) to being worldwide

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5
Q

infection

A

presence & multiplication of a living organism on or in the host

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6
Q

pathogen

A

an organism that causes harm

c. types of pathogens— viruses, bacteria, fungi, protozoan, nematodes and microsporidia

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7
Q

factors whether a host will be infected

A
  • immunocompetence
  • virulence factors of the infecting organism
  • its portal of entry
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8
Q

4 transmission based precautions

A
  • standard precautions
  • contact precautions
  • droplet precautions
  • airborne precautions
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9
Q

standard precautions

A

basic infection prevention
-hand hygiene, use of PPE, respiratory hygiene and cough etiquette, safe injection practices, disinfect soiled surfaces and equipment

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10
Q

contact precautions

A

use when any patient has diarrhea, stool
incontinence, draining wounds or sores, uncontrolled secretions
vomiting, draining body fluids, skin rashes or sores

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11
Q

droplet precautions

A

droplets can be generated by an individual

during coughing, sneezing or talking

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12
Q

airborne precautions

A

use when any individual has a suspected or

known infection that is transmitted by the airborne route

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13
Q

disease stages

A
  • incubation period
  • prodromal stage
  • acute stage
  • convalescent stage
  • resolution
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14
Q

incubation period

A

phase during which the pathogen begins active replication
but doesn’t produce S&Ss; varies in length: salmonella—6 to 8 hrs, hep B—50
to 180 days

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15
Q

prodromal stage

A

initial appearance of S&Ss—may be mild

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16
Q

acute stage

A

maximum impact, with very pronounced & specific S&Ss

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17
Q

convalescent period

A

containment of infection & resolution of S&Ss

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18
Q

resolution

A

total elimination of pathogen without remaining S&Ss

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19
Q

two examples of antibiotic (anti-bacterial)resistance

A

beta lactam antibiotics and vancomycin

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20
Q

beta lactam resistance microbes

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MRSA & resistant

Streptococcus pneumoniae

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21
Q

beta-lactamase

A

enzyme developed from certain microbes that can destroy beta-lactam antibiotics by dismantling the beta lactam ring

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22
Q

MRSA

A

methicillin-resistant Staphylococcus aureas

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23
Q

Staphylococcus aureus

A

is a normal skin flora, and occasionally
can cause infections such as boils and cellulitis in
immunocompetent people

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24
Q

drug that gets rid of MRSA

A

the drug vancomycin is now one of the few drugs that will

destroy MRSA

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25
resistant Streptococcus pneumoniae
new strain of strep developed that makes beta lactamase & now many ear infections are much harder to get rid of
26
VRE—vancomycin-resistant enterococcus
hospital-associated infection,Enterococci faecalis is a normal bowel flora, but in hospitalized people (or residents of nursing homes, etc) will often migrate to urinary tract & other areas
27
cellulitis
-infection of the dermis and subcutaneous tissue
28
cellulitis pathogenesis
an organism such as Staphylococcus aureas that normally dwells on TOP of the skin, or follows a milder staph infection of the skin such as impetigo, (an eruption of blisters usually around nose & mouth that are itchy, crusty, and contagious).
29
botulism
caused by the toxin of Clostridium botulinum, a bacillus that can invade the body via food or soil -toxin heads for neuromuscular nerve synapses & blocks acetylcholine muscle receptor cells
30
botulism S&S
is a descending, symmetric paralysis, including respiratory
31
tetanus
a bacterial disease marked by rigidity and spasms of the voluntary muscles
32
pathogenesis of tetanus disease
caused by Clostridium tetanii, a bacillus which can live in soil as a spore à when deposited in a wound, will then germinate 2) as it becomes active, will release exotoxin tetanospasminà blocks inhibitory neurotransmitters & causes uninterrupted nerve impulses to muscle cellsà can cause jaw muscle tightening called trismus (lockjaw), or more severe tetany -- condition characterized by muscle twitching, cramps, convulsions,
33
Vector-borne disease
transmitted via bite/sting /puncture of a | host creature that then transmits microscopic disease- causing organism into the new body.
34
rabies
a virus transmitted in saliva of infected host, usually by bite to the skin
35
pathogenesis of rabies disease
virus travels via peripheral nervous system (PNS) to the brain & spinal cord (central nervous system -- CNS) and causes brain inflammationà leads to S&S of anxiety, agitation, confusion, convulsions
36
S&S of rabies
anxiety, agitation, confusion, convulsions, production of large amount saliva, plus dysphagia = “foaming at the mouth” & “hydrophobia” (not really a fear of water, just can’t swallow)
37
rabies treatment
treatment needs to begin within first 14 days with postexposure prophylaxis (PEP) -- one dose of rabies immunoglobulin and five doses of rabies vaccine over first 30 days
38
malaria
caused by protozoa that is transmitted via mosquito vector
39
pathogenesis of malaria disease
protozoa reproduces in liver cells (hepatocytes) and then is released into blood, where it infects RBCs & causes them to rupture (hemolysis)à as the RBCs rupture, they trigger a flooding of acute phase reactants into bloodà causes S&S
40
S&S of malaria
high fever, chills, arthralgia, anemia, splenomegaly, cerebral ischemia, heart failure
41
ebola
Rare and deadly, caused by infection with one of five Ebola virus strains. Researchers believe that the virus is animal-borne and that bats are the most likely reservoir
42
S&S of ebola
2) severe headache, rash 3) muscle pain, weakness, fatigue 4) fever > 100.4 F 5) diarrhea / vomiting, or abdominal pain 6) unexplained bleeding, bruising, or hemorrhage 7) leukopenia and thrombocytopenia
43
Transmission and spread ebola
spread through contact with blood and other body fluids.
44
Diagnosis and treatment of ebola
ebola virus is detected in blood only after onset of symptoms, most notably fever. May take up to three days after symptoms begin for the virus to reach detectable levels for laboratory tests and currently no vaccination or specific medication available
45
zika
disease is caused by the Zika virus, which is spread to people primarily through the bite of an infected mosquito
46
S&S of zika
1) people infected with Zika will have no symptoms or mild symptoms 2) fever, rash and joint pain 3) conjunctivitis (red eyes) 4) muscle pain and headache 5) Zika infection during pregnancy can cause a birth defect of the brain called microcephaly and other fetal defects 6) Guillain-Barre syndrome (GBS), an uncommon nervous system illness, is also very likely triggered by Zika in a small number of cases
47
Transmission and spread of zika
spread through mosquito bites –person-to-mosquito-to-person, from a pregnant woman to her fetus, sexual transmission, or blood transfusion
48
diagnosis and treatment of zika
blood or urine test can confirm a diagnosis | currently no vaccination or specific medication available
49
strep throat
caused by Streptococcus pyogenesà invades via coughing, sneezing
50
S&S of strep throat
red, sore throat, often white patches on tonsils
51
scarlet fever
a fever and rash that can cover whole body
52
diphtheria
very contagious upper respiratory infection (URI) caused by bacterium transmitted by cough, sneeze, etc
53
S&S of diphtheria
sore throat, fever, pseudomembrane across tonsils & throat
54
pertussis
a highly contagious disease that is one of the leading causes of vaccine preventable deaths in underdeveloped countries also known as whooping cough
55
S&S of pertussis
horrible violent coughing fits that can be so bad that the person cannot eat & becomes malnourished
56
mumps
virus that invades parotid glands - swelling, fever (main complication is infertility in males)
57
measles/rubeola
an infectious viral disease causing fever and a red rash on skin "two-week measles"
58
S&S of measles/rubeola
dense red maculopapular rash starting on head & going down to body; also fever, cough, runny nose, conjunctivitis
59
rubella
a contagious viral disease with symptoms like mild measles. It can cause fetal malformation if contracted in early pregnancy "three-day measles" or "German Measles"
60
vaicella (chicken Pox)
very contagious—spread via direct inhalation of virus from an infected person exhaling, sneezing, etc and manifests as vesicles (fluid-filled blisters) that begin on trunk and move outward & have different stages of development-- they appear, break, & crust in clusters at different times
61
variola (small pox)
very contagious, inhaled virus, and also manifests as vesicles, but different look & pattern than chicken pox—small pox lesions are dense clusters that are all the same stage, start in the face & extremities and move toward the trunk
62
zoster (singles)
after having chicken pox, the varicella virus remains in one’s system for life, becoming dormant in nervous system like herpes simplex
63
influenza (“flu”)
an acute viral illness of the upper and lower respiratory system with S&S of fever, chills, myalgia, malaise, dry cough, headaches
64
dysentery
this is what infectious diarrhea is called when it is bloody & severe
65
bacillary dysentery
etiology is a bacillus; most common is | shigella
66
amoebic dysentery
etiology is protozoa found in water
67
S&S of dysentery
unlike “regular,” non-bloody diarrhea-causing microbes, the above microbes causes damage to the mucosal surface of the gut, so the diarrhea is characterized by blood & mucous as well as pain with bowel movements—all this is due to infection & inflammation of intestinal lining
68
giardiasis
caused by a protozoa called giardia which is usually contracted by drinking contaminated water but then can be transmitted person-to-person by oral/fecal route
69
patho/S&S of giardia infection
after ingestion, giardia adheres to intestinal wall & interferes with fat absorptionà fat goes straight into the stool.
70
antibiotic -associated diarrhea (pseudomembranous colitis)
caused by being on long-term antibioticsà wipes out normal gut floraà a bacteria called Clostridium difficile (AKA “C-diff”) moves in & causes an inflammatory state of the intestines (“colitis”)