Scenario 17 - haemolytic anaemia Flashcards Preview

Year 3: Amir Sam's DPD lectures > Scenario 17 - haemolytic anaemia > Flashcards

Flashcards in Scenario 17 - haemolytic anaemia Deck (7)
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1
Q

Recall one blood marker that will be very high in haemolytic anaemia?

A

Creatinine

2
Q

What would be seen on a blood film in haemolytic anaemia?

A

Schistocytes

3
Q

Recall 4 symptoms/signs of haemolytic anaemia

A

Splenomegaly
Jaundice
Malaise
Diarrhoea

4
Q

Describe the pathophysiology of microangiopathic haemolytic anaemia (MAHA)

A

Small vessels constrict - red cells break up as they squeeze through them - small clots are formed - vicious cycle begins as vessels narrow further

5
Q

What test can be done to definitively say there is red cell breakdown?

A

D-dimer

6
Q

What is the most common cause of the haemolytic uraemic syndrome?

A

E157 Haemorrhagic E coli

7
Q

What is TTP?

A

Thrombocytic thrombocytopaenic purpura

HUS + fever + neurological manifestations